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X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32854-4
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- Publication type:
- Article
Deep Modeling of Regulating Effects of Small Molecules on Longevity-Associated Genes.
- Published in:
- Pharmaceuticals (14248247), 2021, v. 14, n. 10, p. 948, doi. 10.3390/ph14100948
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- Publication type:
- Article
Bioanalytical Assay Development and Validation for the Pharmacokinetic Study of GMC1, a Novel FKBP52 Co-chaperone Inhibitor for Castration Resistant Prostate Cancer.
- Published in:
- Pharmaceuticals (14248247), 2020, v. 13, n. 11, p. 386, doi. 10.3390/ph13110386
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- Publication type:
- Article
The use of Gene Ontology terms for predicting highly-connected 'hub' nodes in protein-protein interaction networks.
- Published in:
- BMC Systems Biology, 2008, v. 2, p. 1, doi. 10.1186/1752-0509-2-80
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- Publication type:
- Article
Perspectives on the discovery of NOTCH2‐specific inhibitors.
- Published in:
- Chemical Biology & Drug Design, 2018, v. 91, n. 3, p. 691, doi. 10.1111/cbdd.13132
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- Publication type:
- Article
Optimization of Antibacterial Peptides by Genetic Algorithms and Cheminformatics.
- Published in:
- Chemical Biology & Drug Design, 2011, v. 77, n. 1, p. 48, doi. 10.1111/j.1747-0285.2010.01044.x
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- Publication type:
- Article
Development of VPC-70619, a Small-Molecule N-Myc Inhibitor as a Potential Therapy for Neuroendocrine Prostate Cancer.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 5, p. 2588, doi. 10.3390/ijms23052588
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- Publication type:
- Article
Development of Novel Inhibitors Targeting the D-Box of the DNA Binding Domain of Androgen Receptor.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2493, doi. 10.3390/ijms22052493
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- Publication type:
- Article
Dual-Inhibitors of N-Myc and AURKA as Potential Therapy for Neuroendocrine Prostate Cancer.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 21, p. 8277, doi. 10.3390/ijms21218277
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- Publication type:
- Article
Deep Learning Modeling of Androgen Receptor Responses to Prostate Cancer Therapies.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 16, p. 5847, doi. 10.3390/ijms21165847
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- Publication type:
- Article
Computer-Aided Ligand Discovery for Estrogen Receptor Alpha.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 12, p. 4193, doi. 10.3390/ijms21124193
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- Publication type:
- Article
Therapeutic Inhibition of Myc in Cancer. Structural Bases and Computer-Aided Drug Discovery Approaches.
- Published in:
- International Journal of Molecular Sciences, 2019, v. 20, n. 1, p. 120, doi. 10.3390/ijms20010120
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- Publication type:
- Article
Benzothiophenone Derivatives Targeting Mutant Forms of Estrogen Receptor-α in Hormone-Resistant Breast Cancers.
- Published in:
- International Journal of Molecular Sciences, 2018, v. 19, n. 2, p. 579, doi. 10.3390/ijms19020579
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- Publication type:
- Article
Targeting Alternative Sites on the Androgen Receptor to Treat Castration-Resistant Prostate Cancer.
- Published in:
- International Journal of Molecular Sciences, 2013, v. 14, n. 6, p. 12496, doi. 10.3390/ijms140612496
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- Publication type:
- Article
The mycobacterial antibiotic resistance determinant WhiB7 acts as a transcriptional activator by binding the primary sigma factor SigA (RpoV).
- Published in:
- Nucleic Acids Research, 2013, v. 41, n. 22, p. 10062, doi. 10.1093/nar/gkt751
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- Publication type:
- Article
Evaluating Different Descriptors for Model Design of Antimicrobial Peptides with Enhanced Activity Toward P. aeruginosa.
- Published in:
- Chemical Biology & Drug Design, 2007, v. 70, n. 2, p. 134, doi. 10.1111/j.1747-0285.2007.00543.x
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- Publication type:
- Article
DD-GUI: a graphical user interface for deep learning-accelerated virtual screening of large chemical libraries (Deep Docking).
- Published in:
- Bioinformatics, 2022, v. 38, n. 4, p. 1146, doi. 10.1093/bioinformatics/btab771
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- Publication type:
- Article
Keeping pace with the explosive growth of chemical libraries with structure‐based virtual screening.
- Published in:
- WIREs: Computational Molecular Science, 2023, v. 13, n. 6, p. 1, doi. 10.1002/wcms.1678
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- Publication type:
- Article
A Non-Synonymous Coding Variant (L616F) in the <i>TLR5</i> Gene Is Potentially Associated with Crohn's Disease and Influences Responses to Bacterial Flagellin.
- Published in:
- PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061326
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- Publication type:
- Article
Identification of novel host defense peptides and the absence of α-defensins in the bovine genome.
- Published in:
- Proteins, 2008, v. 73, n. 2, p. 420, doi. 10.1002/prot.22059
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- Publication type:
- Article
Indel-based targeting of essential proteins in human pathogens that have close host orthologue(s): Discovery of selective inhibitors for Leishmania donovani elongation factor-1α.
- Published in:
- Proteins, 2007, v. 67, n. 1, p. 53, doi. 10.1002/prot.21278
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- Publication type:
- Article
Large-scale survey for potentially targetable indels in bacterial and protozoan proteins.
- Published in:
- Proteins, 2006, v. 62, n. 2, p. 371, doi. 10.1002/prot.20631
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- Publication type:
- Article
Selective targeting of indel-inferred differences in spatial structures of highly homologous proteins.
- Published in:
- Proteins, 2005, v. 58, n. 4, p. 950, doi. 10.1002/prot.20391
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- Publication type:
- Article
QSAR modeling and computer-aided design of antimicrobial peptides.
- Published in:
- Journal of Peptide Science, 2008, v. 14, n. 1, p. 110, doi. 10.1002/psc.908
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- Publication type:
- Article
Novel Inhibitors of androgen receptor's DNA binding domain identified using an ultra‐large virtual screening.
- Published in:
- Molecular Informatics, 2023, v. 42, n. 8, p. 1, doi. 10.1002/minf.202300026
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- Publication type:
- Article
Rapid Identification of Potential Inhibitors of SARS‐CoV‐2 Main Protease by Deep Docking of 1.3 Billion Compounds.
- Published in:
- Molecular Informatics, 2020, v. 39, n. 8, p. 1, doi. 10.1002/minf.202000028
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- Publication type:
- Article
Cheminformatics Driven Development of Novel Therapies for Drug Resistant Prostate Cancer.
- Published in:
- Molecular Informatics, 2018, v. 37, n. 9/10, p. 1, doi. 10.1002/minf.201800043
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- Publication type:
- Article
Towards Better BBB Passage Prediction Using an Extensive and Curated Data Set.
- Published in:
- Molecular Informatics, 2015, v. 34, n. 5, p. 308, doi. 10.1002/minf.201400118
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- Publication type:
- Article
Discovery of Novel Lin28 Inhibitors to Suppress Cancer Cell Stemness.
- Published in:
- Cancers, 2022, v. 14, n. 22, p. 5687, doi. 10.3390/cancers14225687
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- Publication type:
- Article
Lin28 Regulates Cancer Cell Stemness for Tumour Progression.
- Published in:
- Cancers, 2022, v. 14, n. 19, p. 4640, doi. 10.3390/cancers14194640
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- Publication type:
- Article
Optimization of New Catalytic Topoisomerase II Inhibitors as an Anti-Cancer Therapy.
- Published in:
- Cancers, 2021, v. 13, n. 15, p. 3675, doi. 10.3390/cancers13153675
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- Publication type:
- Article
Development of an Androgen Receptor Inhibitor Targeting the N-Terminal Domain of Androgen Receptor for Treatment of Castration Resistant Prostate Cancer.
- Published in:
- Cancers, 2021, v. 13, n. 14, p. 3488, doi. 10.3390/cancers13143488
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- Publication type:
- Article
Evaluation of Darolutamide (ODM201) Efficiency on Androgen Receptor Mutants Reported to Date in Prostate Cancer Patients.
- Published in:
- Cancers, 2021, v. 13, n. 12, p. 2939, doi. 10.3390/cancers13122939
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- Publication type:
- Article
PurificationDB: database of purification conditions for proteins.
- Published in:
- Database: The Journal of Biological Databases & Curation, 2023, v. 2023, p. 1, doi. 10.1093/database/baad016
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- Publication type:
- Article
Indel PDB: A database of structural insertions and deletions derived from sequence alignments of closely related proteins.
- Published in:
- BMC Bioinformatics, 2008, v. 9, p. 1, doi. 10.1186/1471-2105-9-293
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- Publication type:
- Article
Modeling of cell signaling pathways in macrophages by semantic networks.
- Published in:
- BMC Bioinformatics, 2004, v. 5, p. 156, doi. 10.1186/1471-2105-5-156
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- Publication type:
- Article
Structural characterization of genomes by large scale sequence-structure threading: application of reliability analysis in structural genomics.
- Published in:
- BMC Bioinformatics, 2004, v. 5, p. 101, doi. 10.1186/1471-2105-5-101
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- Publication type:
- Article
An approach to large scale identification of non-obvious structural similarities between proteins.
- Published in:
- BMC Bioinformatics, 2004, v. 5, p. 61, doi. 10.1186/1471-2105-5-61
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- Publication type:
- Article
Structural characterization of genomes by large scale sequence-structure threading.
- Published in:
- BMC Bioinformatics, 2004, v. 5, p. 37, doi. 10.1186/1471-2105-5-37
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- Publication type:
- Article
Review on ''Bioinformatics, Biocomputing and Perl'' by Michael Moorhouse and Paul Barry.
- Published in:
- 2004
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- Publication type:
- Book Review
Ligand Binding Prediction Using Protein Structure Graphs and Residual Graph Attention Networks.
- Published in:
- Molecules, 2022, v. 27, n. 16, p. 5114, doi. 10.3390/molecules27165114
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- Publication type:
- Article
Discovery of New Catalytic Topoisomerase II Inhibitors for Anticancer Therapeutics.
- Published in:
- Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2020.633142
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- Publication type:
- Article
SimBoost: a read-across approach for predicting drug-target binding affinities using gradient boosting machines.
- Published in:
- Journal of Cheminformatics, 2017, v. 9, n. 1, p. 1, doi. 10.1186/s13321-017-0209-z
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- Publication type:
- Article
In silico discovery and validation of potent small-molecule inhibitors targeting the activation function 2 site of human oestrogen receptor α.
- Published in:
- Breast Cancer Research, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13058-015-0529-8
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- Publication type:
- Article
Bioinformatics: A practical guide to the analysis of genes and proteins.
- Published in:
- American Journal of Human Biology, 2005, v. 17, n. 3, p. 387, doi. 10.1002/ajhb.20118
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- Publication type:
- Article
Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models.
- Published in:
- 2020
- By:
- Publication type:
- journal article
SPARC/SFN interaction, suppresses type I collagen in dermal fibroblasts.
- Published in:
- Journal of Cellular Biochemistry, 2012, v. 113, n. 8, p. 2622, doi. 10.1002/jcb.24137
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- Publication type:
- Article
ETS transcription factors as emerging drug targets in cancer.
- Published in:
- Medicinal Research Reviews, 2020, v. 40, n. 1, p. 413, doi. 10.1002/med.21575
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- Publication type:
- Article
Functional analysis of androgen receptor mutations that confer anti-androgen resistance identified in circulating cell-free DNA from prostate cancer patients.
- Published in:
- Genome Biology, 2016, v. 17, p. 1, doi. 10.1186/s13059-015-0864-1
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- Publication type:
- Article
AMPer: a database and an automated discovery tool for antimicrobial peptides.
- Published in:
- Bioinformatics, 2007, v. 23, n. 9, p. 1148, doi. 10.1093/bioinformatics/btm068
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- Publication type:
- Article