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- Title
Prolonged intrahepatic cholestasis secondary to acute hepatitis A.
- Authors
Gordon, Stuart C.; Reddy, Rajender; Schiff, Leon; Schiff, Eugene R.; Gordon, S C; Reddy, K R; Schiff, L; Schiff, E R
- Abstract
Viral hepatitis characterized by prolonged cholestasis has not been associated with a specific serologic marker. We report the cases of six patients presenting with a clinical syndrome typical of cholestatic hepatitis who were subsequently found to have acute hepatitis A. Usual features include pruritus, fever, diarrhea, and weight loss with serum bilirubin levels greater than 10 mg/dL, and a clinical course lasting at least 12 weeks. All patients recovered completely without sequelae. Knowledge of this unusual manifestation of hepatitis A may help avoid potentially invasive procedures involved in the evaluation of suspected obstructive jaundice and facilitate appropriate immunoprophylactic measures.
- Subjects
CHOLESTASIS; VIRAL hepatitis
- Publication
Annals of Internal Medicine, 1984, Vol 101, Issue 5, p635
- ISSN
0003-4819
- Publication type
journal article
- DOI
10.7326/0003-4819-101-5-635