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Feasibility, safety, and indications for surgical biopsy of intrinsic brainstem tumors in children.
Published in:
Child's Nervous System, 2013, v. 29, n. 8, p. 1313, doi. 10.1007/s00381-013-2101-0
By:
- Cage, Tene;
- Samagh, Sonia;
- Mueller, Sabine;
- Nicolaides, Theodore;
- Haas-Kogan, Daphne;
- Prados, Michael;
- Banerjee, Anu;
- Auguste, Kurtis;
- Gupta, Nalin
Publication type:
Article
Comparison of Volumetric and 2D Measurements and Longitudinal Trajectories in the Response Assessment of BRAF V600E-Mutant Pediatric Gliomas in the Pacific Pediatric Neuro-Oncology Consortium Clinical Trial.
Published in:
American Journal of Neuroradiology, 2024, v. 45, n. 4, p. 475, doi. 10.3174/ajnr.A8189
By:
- Ramakrishnan, Divya;
- Brüningk, Sarah C.;
- von Reppert, Marc;
- Memon, Fatima;
- Maleki, Nazanin;
- Aneja, Sanjay;
- Kazerooni, Anahita Fathi;
- Nabavizadeh, Ali;
- MingDe Lin;
- Bousabarah, Khaled;
- Molinaro, Annette;
- Nicolaides, Theodore;
- Prados, Michael;
- Mueller, Sabine;
- Aboian, Mariam S.
Publication type:
Article
Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma.
Published in:
Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01463-z
By:
- Zhao, Guisheng;
- Newbury, Patrick;
- Ishi, Yukitomo;
- Chekalin, Eugene;
- Zeng, Billy;
- Glicksberg, Benjamin S.;
- Wen, Anita;
- Paithankar, Shreya;
- Sasaki, Takahiro;
- Suri, Amreena;
- Nazarian, Javad;
- Pacold, Michael E.;
- Brat, Daniel J.;
- Nicolaides, Theodore;
- Chen, Bin;
- Hashizume, Rintaro
Publication type:
Article
LSD1 inhibition in pHGG: the key to unleashing immunotherapy?
Published in:
Neuro-Oncology, 2020, v. 22, n. 9, p. 1237, doi. 10.1093/neuonc/noaa171
By:
- Nicolaides, Theodore P;
- Hashizume, Rintaro
Publication type:
Article
Molecular profiling and targeted therapy in pediatric gliomas: review and consensus recommendations.
Published in:
Neuro-Oncology, 2019, v. 21, n. 8, p. 968, doi. 10.1093/neuonc/noz022
By:
- Miklja, Zachary;
- Pasternak, Amy;
- Stallard, Stefanie;
- Nicolaides, Theodore;
- Kline-Nunnally, Cassie;
- Cole, Bonnie;
- Beroukhim, Rameen;
- Bandopadhayay, Pratiti;
- Chi, Susan;
- Ramkissoon, Shakti H;
- Mullan, Brendan;
- Bruzek, Amy K;
- Gauthier, Angela;
- Garcia, Taylor;
- Atchison, Christie;
- Marini, Bernard;
- Fouladi, Maryam;
- Parsons, D William;
- Leary, Sarah;
- Mueller, Sabine
Publication type:
Article
THER-26. PHARMACOKINETIC AND UPDATED OUTCOME DATA FROM PNOC-002: A SAFETY STUDY OF VEMURAFENIB, AN ORAL INHIBITOR OF BRAFV600E, IN CHILDREN WITH RECURRENT/REFRACTORY BRAFV600E MUTANT BRAIN TUMORS.
Published in:
Neuro-Oncology, 2019, v. 21, p. ii119, doi. 10.1093/neuonc/noz036.231
By:
- Nicolaides, Theodore;
- Margol, Ashley;
- Gajjar, Amar;
- Goldman, Stewart;
- Gauvain, Karen;
- Kilburn, Lindsay;
- Nazemi, Kellie;
- Minturn, Jane;
- Leary, Sarah;
- Whipple, Nicholas;
- Gururangan, Sridharan;
- Crawford, John;
- Long-Boyle, Janel;
- Wang, Hechuan;
- Ivaturi, Vijay;
- Aboian, Mariam;
- Molinaro, Annette;
- Mueller, Sabine;
- Prados, Michael
Publication type:
Article
THER-17. BRAF-V600E DEGRADATION AS A THERAPEUTIC STRATEGY IN BRAF-V600E MUTANT GLIOMAS.
Published in:
Neuro-Oncology, 2019, v. 21, p. ii117, doi. 10.1093/neuonc/noz036.224
By:
- Zhao, Guisheng;
- Muldoon, Daniel;
- Mo, Xiulei;
- Tang, Cong;
- Fu, Haian;
- Gustafson, W Clay;
- Weiss, William A;
- Nicolaides, Theodore
Publication type:
Article
LGG-10. TUMOR-ASSOCIATED IMMUNE RESPONSE IN ANAPLASTIC PROGRESSION OF PXA.
Published in:
Neuro-Oncology, 2019, v. 21, p. ii100, doi. 10.1093/neuonc/noz036.153
By:
- Kumar, Anupam;
- Chen, Katharine;
- Patel, Sonia;
- Petritsch, Claudia;
- Nicolaides, Theodore;
- Solomon, David A;
- Phillips, Joanna J
Publication type:
Article
DIPG-19. REVERSAL OF CANCER GENE EXPRESSION IDENTIFIES NOVEL THERAPEUTICS FOR DIFFUSE INTRINSIC PONTINE GLIOMA.
Published in:
Neuro-Oncology, 2019, v. 21, p. ii72, doi. 10.1093/neuonc/noz036.040
By:
- Zhao, Guisheng;
- Newbury, Patrick;
- Zeng, William;
- Muldoon, Daniel;
- Glicksberg, Benjamin S;
- Wen, Anita;
- Liu, Ke;
- Chen, Bin;
- Nicolaides, Theodore
Publication type:
Article
A phase I trial of the MEK inhibitor selumetinib (AZD6244) in pediatric patients with recurrent or refractory low-grade glioma: a Pediatric Brain Tumor Consortium (PBTC) study.
Published in:
Neuro-Oncology, 2017, v. 19, n. 8, p. 1135, doi. 10.1093/neuonc/now282
By:
- Banerjee, Anuradha;
- Jakacki, Regina I.;
- Onar-Thomas, Arzu;
- Shengjie Wu;
- Nicolaides, Theodore;
- Poussaint, Tina Young;
- Fangusaro, Jason;
- Phillips, Joanna;
- Perry, Arie;
- Turner, David;
- Prados, Michael;
- Packer, Roger J.;
- Qaddoumi, Ibrahim;
- Gururangan, Sridharan;
- Pollack, Ian F.;
- Goldman, Stewart;
- Doyle, Lawrence A.;
- Stewart, Clinton F.;
- Boyett, James M.;
- Kun, Larry E.
Publication type:
Article
TARGETING RESISTANCE PATHWAYS IN BRAF-MUTANT PEDIATRIC GLIOMAS.
Published in:
Neuro-Oncology, 2014, v. 16, n. suppl_3, p. iii27, doi. 10.1093/neuonc/nou208.18
By:
- Nicolaides, Theodore;
- Yao, Tsun Wen;
- Yoshida, Yasuyuki;
- Zhang, Jie;
- Ozawa, Tomoko;
- James, David
Publication type:
Article
The genetic landscape of anaplastic pleomorphic xanthoastrocytoma.
Published in:
Brain Pathology, 2019, v. 29, n. 1, p. 85, doi. 10.1111/bpa.12639
By:
- Phillips, Joanna J.;
- Gong, Henry;
- Chen, Katharine;
- Joseph, Nancy M.;
- van Ziffle, Jessica;
- Bastian, Boris C.;
- Grenert, James P.;
- Kline, Cassie N.;
- Mueller, Sabine;
- Banerjee, Anuradha;
- Nicolaides, Theodore;
- Gupta, Nalin;
- Berger, Mitchel S.;
- Lee, Han S.;
- Pekmezci, Melike;
- Tihan, Tarik;
- Bollen, Andrew W.;
- Perry, Arie;
- Shieh, Joseph T.C.;
- Solomon, David A.
Publication type:
Article
Consensus molecular subtyping of metastatic colorectal cancer expands biomarker-directed therapeutic benefit for patients with CMS1 and CMS2 tumors.
Published in:
British Journal of Cancer, 2024, v. 131, n. 8, p. 1328, doi. 10.1038/s41416-024-02826-0
By:
- Chowdhury, Saikat;
- Xiu, Joanne;
- Ribeiro, Jennifer R.;
- Nicolaides, Theodore;
- Zhang, Jian;
- Korn, W. Michael;
- Poorman, Kelsey A.;
- Lenz, Heinz-Josef;
- Marshall, John L.;
- Oberley, Matthew J.;
- Sledge Jr., George W.;
- Spetzler, David;
- Kopetz, Scott;
- Shen, John Paul
Publication type:
Article
Pediatric glioblastoma in the setting of constitutional mismatch-repair deficiency treated with upfront lomustine and nivolumab.
Published in:
Pediatric Blood & Cancer, 2024, v. 71, n. 1, p. 1, doi. 10.1002/pbc.30757
By:
- Krugman, Jessica;
- Patel, Krupesh;
- Cantor, Anna;
- Snuderl, Matija;
- Cooper, Benjamin;
- Zan, Elcin;
- Radmanesh, Ali;
- Hidalgo, E. Teresa;
- Nicolaides, Theodore
Publication type:
Article
Radiologic response to MEK inhibition in a patient with a WNT‐activated craniopharyngioma.
Published in:
Pediatric Blood & Cancer, 2021, v. 68, n. 3, p. 1, doi. 10.1002/pbc.28753
By:
- Patel, Krupesh;
- Allen, Jeffrey;
- Zagzag, David;
- Wisoff, Jeffrey;
- Radmanesh, Alireza;
- Gindin, Tatyana;
- Nicolaides, Theodore
Publication type:
Article
Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.
Published in:
Acta Neuropathologica, 2018, v. 135, n. 4, p. 635, doi. 10.1007/s00401-018-1819-x
By:
- Iorgulescu, J. Bryan;
- Van Ziffle, Jessica;
- Stevers, Meredith;
- Grenert, James P.;
- Bastian, Boris C.;
- Chavez, Lukas;
- Stichel, Damian;
- Buchhalter, Ivo;
- Samuel, David;
- Nicolaides, Theodore;
- Banerjee, Anuradha;
- Mueller, Sabine;
- Gupta, Nalin;
- Tihan, Tarik;
- Bollen, Andrew W.;
- Northcott, Paul A.;
- Kool, Marcel;
- Pfister, Stefan;
- Korshunov, Andrey;
- Perry, Arie
Publication type:
Article
Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation.
Published in:
2016
By:
- Phillips, Joanna;
- Gong, Henry;
- Chen, Katharine;
- Joseph, Nancy;
- Ziffle, Jessica;
- Jin, Lee-Way;
- Bastian, Boris;
- Bollen, Andrew;
- Perry, Arie;
- Nicolaides, Theodore;
- Solomon, David;
- Shieh, Joseph
Publication type:
Letter
Population Pharmacokinetics of Vemurafenib in Children With Recurrent/Refractory BRAF Gene V600E‐Mutant Astrocytomas.
Published in:
Journal of Clinical Pharmacology, 2020, v. 60, n. 9, p. 1209, doi. 10.1002/jcph.1617
By:
- Wang, Hechuan;
- Long‐Boyle, Janel;
- Winger, Beth Apsel;
- Nicolaides, Theodore;
- Mueller, Sabine;
- Prados, Michael;
- Ivaturi, Vijay
Publication type:
Article
High-dose chemotherapy with autologous stem-cell rescue in the treatment of patients with recurrent non-cerebellar primitive neuroectodermal tumors.
Published in:
Pediatric Blood & Cancer, 2004, v. 42, n. 3, p. 261, doi. 10.1002/pbc.10369
By:
- Broniscer, Alberto;
- Nicolaides, Theodore P.;
- Dunkel, Ira J.;
- Gardner, Sharon L.;
- Johnson, James;
- Allen, Jeffrey C.;
- Sposto, Richard;
- Finlay, Jonathan L.
Publication type:
Article
Reirradiation and PD-1 inhibition with nivolumab for the treatment of recurrent diffuse intrinsic pontine glioma: a single-institution experience.
Published in:
Journal of Neuro-Oncology, 2018, v. 140, n. 3, p. 629, doi. 10.1007/s11060-018-2991-5
By:
- Kline, Cassie;
- Liu, S. John;
- Duriseti, Sai;
- Banerjee, Anuradha;
- Nicolaides, Theodore;
- Raber, Shannon;
- Gupta, Nalin;
- Haas-Kogan, Daphne;
- Braunstein, Steve;
- Mueller, Sabine
Publication type:
Article
Precision knockdown of EGFR gene expression using radio frequency electromagnetic energy.
Published in:
Journal of Neuro-Oncology, 2017, v. 133, n. 2, p. 257, doi. 10.1007/s11060-017-2440-x
By:
- Ulasov, Ilya;
- Foster, Haidn;
- Butters, Mike;
- Yoon, Jae-Geun;
- Ozawa, Tomoko;
- Nicolaides, Theodore;
- Figueroa, Xavier;
- Hothi, Parvinder;
- Prados, Michael;
- Butters, John;
- Cobbs, Charles
Publication type:
Article
Combined BRAF and MEK blockade for BRAF-mutant gliomas.
Published in:
Journal of Neuro-Oncology, 2017, v. 131, n. 3, p. 495, doi. 10.1007/s11060-016-2333-4
By:
- Zhang, Jie;
- Yao, Tsun-Wen;
- Hashizume, Rintaro;
- Hariono, Sujatmi;
- Barkovich, Krister;
- Fan, Qi-Wen;
- Prados, Michael;
- James, C.;
- Weiss, William;
- Nicolaides, Theodore
Publication type:
Article
Erratum to: Survival advantage combining a BRAF inhibitor and radiation in BRAF V600E-mutant glioma.
Published in:
2016
By:
- Dasgupta, Tina;
- Olow, Aleksandra;
- Yang, Xiaodong;
- Hashizume, Rintaro;
- Nicolaides, Theodore;
- Tom, Maxwell;
- Aoki, Yasuyuki;
- Berger, Mitchel;
- Weiss, William;
- Stalpers, Lukas;
- Prados, Michael;
- James, C.;
- Mueller, Sabine;
- Haas-Kogan, Daphne
Publication type:
Erratum
Survival advantage combining a BRAF inhibitor and radiation in BRAF V600E-mutant glioma.
Published in:
Journal of Neuro-Oncology, 2016, v. 126, n. 3, p. 385, doi. 10.1007/s11060-015-1939-2
By:
- Dasgupta, Tina;
- Olow, Aleksandra;
- Yang, Xiaodong;
- Hashizume, Rintaro;
- Nicolaides, Theodore;
- Tom, Maxwell;
- Aoki, Yasuyuki;
- Berger, Mitchel;
- Weiss, William;
- Stalpers, Lukas;
- Prados, Michael;
- David James, C.;
- Mueller, Sabine;
- Haas-Kogan, Daphne
Publication type:
Article
Pure germinomas of the central nervous system: treatment strategies and outcomes.
Published in:
Journal of Neuro-Oncology, 2014, v. 120, n. 3, p. 643, doi. 10.1007/s11060-014-1599-7
By:
- Schoenfeld, Adam;
- Haas-Kogan, Daphne;
- Molinaro, Annette;
- Banerjee, Anu;
- Nicolaides, Theodore;
- Tihan, Tarik;
- Bollen, Andrew;
- Gupta, Nalin;
- Mueller, Sabine
Publication type:
Article
Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment.
Published in:
Journal of Neuro-Oncology, 2012, v. 110, n. 3, p. 305, doi. 10.1007/s11060-012-0973-6
By:
- Hashizume, Rintaro;
- Smirnov, Ivan;
- Liu, Sharon;
- Phillips, Joanna;
- Hyer, Jeanette;
- McKnight, Tracy;
- Wendland, Michael;
- Prados, Michael;
- Banerjee, Anu;
- Nicolaides, Theodore;
- Mueller, Sabine;
- James, Charles;
- Gupta, Nalin
Publication type:
Article
High-dose chemotherapy and autologous stem cell rescue for atypical teratoid/rhabdoid tumor of the central nervous system.
Published in:
Journal of Neuro-Oncology, 2010, v. 98, n. 1, p. 117, doi. 10.1007/s11060-009-0071-6
By:
- Nicolaides, Theodore;
- Tihan, Tarik;
- Horn, Biljana;
- Biegel, Jaclyn;
- Prados, Michael;
- Banerjee, Anuradha
Publication type:
Article
Akt and Autophagy Cooperate to Promote Survival of Drug-Resistant Glioma.
Published in:
Science Signaling, 2010, v. 3, n. 147, p. 1, doi. 10.1126/scisignal.2001017
By:
- Qi-Wen Fan;
- Christine Cheng;
- Hackett, Chris;
- Feldman, Morri;
- Houseman, Benjamin T.;
- Nicolaides, Theodore;
- Haas-Kogan, Daphne;
- David James, C.;
- Oakes, Scott A.;
- Debnath, Jayanta;
- Shokat, Kevan M.;
- Weiss, William A.
Publication type:
Article

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