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- Title
Modular Access to Highly Functionalised Tetrahydroquinolines.
- Authors
Cordero, Franca M.; Khairnar, Bhushan B.; Brandi, Alberto
- Abstract
Highly functionalised tetrahydroquinolines have been obtained by a modular approach consisting of a nitrone 1,3-dipolar cycloaddition to 2-bromostyrene followed by isoxazolidine N-O cleavage and copper-catalysed aromatic N-substitution/cyclisation. A 1,2,3,4-tetrahydro-1,8-naphthyridine was obtained in the same way.
- Subjects
NITROGEN; HETEROCYCLIC compounds; RING formation (Chemistry); ISOXAZOLIDINES; NAPHTHYRIDINES
- Publication
European Journal of Organic Chemistry, 2014, Vol 2014, Issue 32, p7122
- ISSN
1434-193X
- Publication type
Article
- DOI
10.1002/ejoc.201403025