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- Title
A Systematic Review and Network Meta-analyses to Assess the Effectiveness of Human Immunodeficiency Virus (HIV) Self-testing Distribution Strategies.
- Authors
Eshun-Wilson, Ingrid; Jamil, Muhammad S; Witzel, T Charles; Glidded, David V; Johnson, Cheryl; Trouneau, Noelle Le; Ford, Nathan; McGee, Kathleen; Kemp, Chris; Baral, Stefan; Schwartz, Sheree; Geng, Elvin H
- Abstract
Background We conducted a systematic review and network meta-analysis to identify which human immunodeficiency virus (HIV) self-testing (HIVST) distribution strategies are most effective. Methods We abstracted data from randomized controlled trials and observational studies published between 4 June 2006 and 4 June 2019. Results We included 33 studies, yielding 6 HIVST distribution strategies. All distribution strategies increased testing uptake compared to standard testing: in sub-Saharan Africa, partner HIVST distribution ranked highest (78% probability); in North America, Asia, and the Pacific regions, web-based distribution ranked highest (93% probability), and facility based distribution ranked second in all settings. Across HIVST distribution strategies HIV positivity and linkage was similar to standard testing. Conclusions A range of HIVST distribution strategies are effective in increasing HIV testing. HIVST distribution by sexual partners, web-based distribution, as well as health facility distribution strategies should be considered for implementation to expand the reach of HIV testing services.
- Subjects
DIAGNOSIS of HIV infections; SELF diagnosis; DIAGNOSTIC reagents &; test kits; CINAHL database; PSYCHOLOGY information storage &; retrieval systems; META-analysis; MEDICAL information storage &; retrieval systems; INFORMATION storage &; retrieval systems; MEDICAL databases; SYSTEMATIC reviews; MEDLINE
- Publication
Clinical Infectious Diseases, 2021, Vol 73, Issue 4, pe1018
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciab029