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- Title
Influence of smoking on spinal fusion after spondylodesis surgery: A comparative clinical study.
- Authors
Hermann, Pia C.; Webler, Markus; Bornemann, Rahel; Jansen, Tom R.; Rommelspacher, Yorck; Sander, Kirsten; Roessler, Philip P.; Frey, Sönke P.; Pflugmacher, Robert
- Abstract
<bold>Background: </bold>Smoking is a risk factor in the process of bone healing after lumbar spondylodesis, often associated with complications that occur intraoperatively or during follow-up periods.<bold>Objective: </bold>To assess if smokers yield worse results concerning lumbar interbody fusion than non-smokers in a clinical comparative setting.<bold>Methods: </bold>Spondylodesis outcomes in 50 patients, 34 non-smokers (mean 58 years; (range 29-81) and 16 smokers (mean 47 years; range 29-75) were compared preoperatively and one year after spondylodesis surgery using Oswestry-Disability-Index (ODI), visual analogue scale (VAS) and radiological outcome analysis of fusion-success.<bold>Results: </bold>Smokers showed a comparable ODI-improvement (p = 0.9343) and pain reduction to non-smokers (p = 0.5451). The intake of opioids was only reduced in non-smokers one year after surgery. Fusion success was significantly better in non-smokers (p = 0.01).<bold>Conclusions: </bold>The results indicate that smoking adversely effects spinal fusion. Particularly re-operations caused by pseudarthrosis occur at a higher rate in smokers than in non-smokers.
- Subjects
SPINAL fusion; SPONDYLOSIS; HEALTH; SMOKING; DISEASE complications; SURGICAL complications; THERAPEUTICS; LUMBAR vertebrae surgery; ANALGESICS; COMPARATIVE studies; RESEARCH methodology; MEDICAL cooperation; NARCOTICS; RESEARCH; EVALUATION research
- Publication
Technology & Health Care, 2016, Vol 24, Issue 5, p737
- ISSN
0928-7329
- Publication type
journal article
- DOI
10.3233/THC-161164