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Natural History of a Mouse Model Overexpressing the Dp71 Dystrophin Isoform.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 23, p. 12617, doi. 10.3390/ijms222312617
By:
- Lim, Kenji Rowel Q.;
- Shah, Md Nur Ahad;
- Woo, Stanley;
- Wilton-Clark, Harry;
- Zhabyeyev, Pavel;
- Wang, Faqi;
- Maruyama, Rika;
- Oudit, Gavin Y.;
- Yokota, Toshifumi
Publication type:
Article
Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1691, doi. 10.3390/ijms22041691
By:
- Jamieson, K. Lockhart;
- Darwesh, Ahmed M.;
- Sosnowski, Deanna K.;
- Zhang, Hao;
- Shah, Saumya;
- Zhabyeyev, Pavel;
- Yang, Jun;
- Hammock, Bruce D.;
- Edin, Matthew L.;
- Zeldin, Darryl C.;
- Oudit, Gavin Y.;
- Kassiri, Zamaneh;
- Seubert, John M.;
- Das, Anindita
Publication type:
Article
Electroporation-induced inward current in voltage-clamped guinea pig ventricular myocytes.
Published in:
2010
By:
- Dyachok, Oksana;
- Zhabyeyev, Pavel;
- McDonald, Terence;
- McDonald, Terence F
Publication type:
journal article
Block of cardiac delayed-rectifier and inward-rectifier K [Sub+] currents by nisoldipine.
Published in:
British Journal of Pharmacology, 2003, v. 140, n. 5, p. 863, doi. 10.1038/sj.bjp.0705518
By:
- Missan, Sergey;
- Zhabyeyev, Pavel;
- Dyachok, Oksana;
- Jones, Stephen E.;
- McDonald, Terence F.
Publication type:
Article
Selective phenylalkylamine block of IKr over other K+ currents in guinea-pig ventricular myocytes.
Published in:
British Journal of Pharmacology, 2000, v. 131, n. 8, p. 1809, doi. 10.1038/sj.bjp.0703758
By:
- Jones, Stephen E;
- Missan, Sergey;
- Zhabyeyev, Pavel;
- McDonald, Terence F
Publication type:
Article
Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy.
Published in:
Scientific Reports, 2015, p. 18132, doi. 10.1038/srep18132
By:
- Das, Subhash K.;
- Wang, Wang;
- Zhabyeyev, Pavel;
- Basu, Ratnadeep;
- McLean, Brent;
- Fan, Dong;
- Parajuli, Nirmal;
- DesAulniers, Jessica;
- Patel, Vaibhav B.;
- Hajjar, Roger J.;
- Dyck, Jason R. B.;
- Kassiri, Zamaneh;
- Oudit, Gavin Y.
Publication type:
Article
PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07812-8
By:
- Patel, Vaibhav B.;
- Zhabyeyev, Pavel;
- Chen, Xueyi;
- Wang, Faqi;
- Paul, Manish;
- Fan, Dong;
- McLean, Brent A.;
- Basu, Ratnadeep;
- Zhang, Pu;
- Shah, Saumya;
- Dawson, John F.;
- Pyle, W. Glen;
- Hazra, Mousumi;
- Kassiri, Zamaneh;
- Hazra, Saugata;
- Vanhaesebroeck, Bart;
- McCulloch, Christopher A.;
- Oudit, Gavin Y.
Publication type:
Article
Advanced iron-overload cardiomyopathy in a genetic murine model is rescued by resveratrol therapy.
Published in:
Bioscience Reports, 2018, v. 38, n. 1, p. 1, doi. 10.1042/BSR20171302
By:
- Das, Subhash K.;
- Zhabyeyev, Pavel;
- Basu, Ratnadeep;
- Patel, Vaibhav B.;
- Dyck, Jason R. B.;
- Kassiri, Zamaneh;
- Oudit, Gavin Y.
Publication type:
Article
Endothelial and cardiomyocyte PI3Kβ divergently regulate cardiac remodelling in response to ischaemic injury.
Published in:
Cardiovascular Research, 2019, v. 115, n. 8, p. 1343, doi. 10.1093/cvr/cvy298
By:
- Chen, Xueyi;
- Zhabyeyev, Pavel;
- Azad, Abul K;
- Wang, Wang;
- Minerath, Rachel A;
- DesAulniers, Jessica;
- Grueter, Chad E;
- Murray, Allan G;
- Kassiri, Zamaneh;
- Vanhaesebroeck, Bart;
- Oudit, Gavin Y
Publication type:
Article
PI3Kα is essential for the recovery from Cre/tamoxifen cardiotoxicity and in myocardial insulin signalling but is not required for normal myocardial contractility in the adult heart.
Published in:
Cardiovascular Research, 2015, v. 105, n. 3, p. 292, doi. 10.1093/cvr/cvv016
By:
- McLean, Brent A.;
- Zhabyeyev, Pavel;
- Patel, Vaibhav B.;
- Basu, Ratnadeep;
- Parajuli, Nirmal;
- DesAulniers, Jessica;
- Murray, Allan G.;
- Kassiri, Zamaneh;
- Vanhaesebroeck, Bart;
- Oudit, Gavin Y.
Publication type:
Article
Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload.
Published in:
Cardiovascular Research, 2013, v. 97, n. 4, p. 676, doi. 10.1093/cvr/cvs424
By:
- Zhabyeyev, Pavel;
- Gandhi, Manoj;
- Mori, Jun;
- Basu, Ratnadeep;
- Kassiri, Zamaneh;
- Clanachan, Alexander;
- Lopaschuk, Gary D.;
- Oudit, Gavin Y.
Publication type:
Article
Osmotic modulation of slowly activating IKs in guinea-pig ventricular myocytes.
Published in:
Cardiovascular Research, 2011, v. 91, n. 3, p. 429, doi. 10.1093/cvr/cvr074
By:
- Missan, Sergey;
- Shuba, Lesya M.;
- Zhabyeyev, Pavel;
- McDonald, Terence F.
Publication type:
Article
Loss of apelin blocks the emergence of sprouting angiogenesis in experimental tumors.
Published in:
FASEB Journal, 2022, v. 36, n. 10, p. 1, doi. 10.1096/fj.202200616RR
By:
- Azad, Abul K.;
- Campbell, Kieran R.;
- Zhabyeyev, Pavel;
- Oudit, Gavin Y.;
- Moore, Ronald B.;
- Murray, Allan G.
Publication type:
Article
RPI‐194 is a Novel Troponin Activator that Increases the Calcium Sensitivity of Striated Muscle Contraction.
Published in:
FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.0R342
By:
- Mahmud, Zabed;
- Tikunova, Svetlana;
- Belevych, Natalya;
- Wagg, Corey;
- Zhabyeyev, Pavel;
- Liu, Philip B.;
- Rasicci, David V.;
- Schulz, Richard;
- Yengo, Christopher M.;
- Oudit, Gavin Y.;
- Lopaschuk, Gary D.;
- Reiser, Peter J.;
- Davis, Jonathan P.;
- Hwang, Peter M.
Publication type:
Article
Gelsolin is an important mediator of Angiotensin II‐induced activation of cardiac fibroblasts and fibrosis.
Published in:
FASEB Journal, 2021, v. 35, n. 10, p. 1, doi. 10.1096/fj.202100038RR
By:
- Jana, Sayantan;
- Aujla, Preetinder;
- Hu, Mei;
- Kilic, Tolga;
- Zhabyeyev, Pavel;
- McCulloch, Christopher A.;
- Oudit, Gavin Y.;
- Kassiri, Zamaneh
Publication type:
Article
Loss of PI3Kα Mediates Protection From Myocardial Ischemia-Reperfusion Injury Linked to Preserved Mitochondrial Function.
Published in:
Journal of the American Heart Association, 2023, v. 12, n. 12, p. 1, doi. 10.1161/JAHA.122.022352
By:
- Zhabyeyev, Pavel;
- McLean, Brent;
- Bassiouni, Wesam;
- Valencia, Robert;
- Paul, Manish;
- Darwesh, Ahmed M.;
- Seubert, John M.;
- Hazra, Saugata;
- Oudit, Gavin Y.
Publication type:
Article
PI3Kα Pathway Inhibition With Doxorubicin Treatment Results in Distinct Biventricular Atrophy and Remodeling With Right Ventricular Dysfunction.
Published in:
2019
By:
- McLean, Brent A.;
- Patel, Vaibhav B.;
- Zhabyeyev, Pavel;
- Xueyi Chen;
- Basu, Ratnadeep;
- Faqi Wang;
- Shah, Saumya;
- Vanhaesebroeck, Bart;
- Oudit, Gavin Y.;
- Chen, Xueyi;
- Wang, Faqi
Publication type:
journal article
Insensitivity of cardiac delayed-rectifier IKr to tyrosine phosphorylation inhibitors and stimulators.
Published in:
British Journal of Pharmacology, 2006, v. 148, n. 5, p. 724, doi. 10.1038/sj.bjp.0706776
By:
- Missan, Sergey;
- Zhabyeyev, Pavel;
- Linsdell, Paul;
- Mc Donald, Terence F
Publication type:
Article
Cardiovascular toxicity of PI3Ka inhibitors.
Published in:
Clinical Science, 2020, v. 134, n. 19, p. 2596, doi. 10.1042/CS20200302
By:
- Sadasivan, Chandu;
- Zhabyeyev, Pavel;
- Labib, Dina;
- White, James A.;
- Paterson, D. Ian;
- Oudit, Gavin Y.
Publication type:
Article
Small Molecule RPI-194 Stabilizes Activated Troponin to Increase the Calcium Sensitivity of Striated Muscle Contraction.
Published in:
Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.892979
By:
- Mahmud, Zabed;
- Tikunova, Svetlana;
- Belevych, Natalya;
- Wagg, Cory S.;
- Zhabyeyev, Pavel;
- Liu, Philip B.;
- Rasicci, David V.;
- Yengo, Christopher M.;
- Oudit, Gavin Y.;
- Lopaschuk, Gary D.;
- Reiser, Peter J.;
- Davis, Jonathan P.;
- Hwang, Peter M.
Publication type:
Article
Unravelling the molecular basis for cardiac iron metabolism and deficiency in heart failure.
Published in:
European Heart Journal, 2017, v. 38, n. 5, p. 373, doi. 10.1093/eurheartj/ehw386
By:
- Zhabyeyev, Pavel;
- Oudit, Gavin Y.
Publication type:
Article

Found: 21

Natural History of a Mouse Model Overexpressing the Dp71 Dystrophin Isoform.

Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury.

Electroporation-induced inward current in voltage-clamped guinea pig ventricular myocytes.

Block of cardiac delayed-rectifier and inward-rectifier K [Sub+] currents by nisoldipine.

Selective phenylalkylamine block of I<sub>Kr</sub> over other K<sup>+</sup> currents in guinea-pig ventricular myocytes.

Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy.

PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease.

Advanced iron-overload cardiomyopathy in a genetic murine model is rescued by resveratrol therapy.

Endothelial and cardiomyocyte PI3Kβ divergently regulate cardiac remodelling in response to ischaemic injury.

PI3Kα is essential for the recovery from Cre/tamoxifen cardiotoxicity and in myocardial insulin signalling but is not required for normal myocardial contractility in the adult heart.

Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload.

Osmotic modulation of slowly activating IKs in guinea-pig ventricular myocytes.

Loss of apelin blocks the emergence of sprouting angiogenesis in experimental tumors.

RPI‐194 is a Novel Troponin Activator that Increases the Calcium Sensitivity of Striated Muscle Contraction.

Gelsolin is an important mediator of Angiotensin II‐induced activation of cardiac fibroblasts and fibrosis.

Loss of PI3Kα Mediates Protection From Myocardial Ischemia-Reperfusion Injury Linked to Preserved Mitochondrial Function.

PI3Kα Pathway Inhibition With Doxorubicin Treatment Results in Distinct Biventricular Atrophy and Remodeling With Right Ventricular Dysfunction.

Insensitivity of cardiac delayed-rectifier I<sub>Kr</sub> to tyrosine phosphorylation inhibitors and stimulators.

Cardiovascular toxicity of PI3Ka inhibitors.

Small Molecule RPI-194 Stabilizes Activated Troponin to Increase the Calcium Sensitivity of Striated Muscle Contraction.

Unravelling the molecular basis for cardiac iron metabolism and deficiency in heart failure.