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Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-07025-6
By:
- Wang, Chris Kedong;
- Nelepcu, Irina;
- Hui, Desmond;
- Oo, Htoo Zarni;
- Truong, Sarah;
- Zhao, Sarah;
- Tahiry, Zakir;
- Esfandnia, Shaghayegh;
- Ghaidi, Fariba;
- Adomat, Hans;
- Dagil, Robert;
- Gustavsson, Tobias;
- Choudhary, Swati;
- Salanti, Ali;
- Sorensen, Poul H.;
- Al Nakouzi, Nader;
- Daugaard, Mads
Publication type:
Article
Reformation of the chondroitin sulfate glycocalyx enables progression of AR-independent prostate cancer.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32530-7
By:
- Al-Nakouzi, Nader;
- Wang, Chris Kedong;
- Oo, Htoo Zarni;
- Nelepcu, Irina;
- Lallous, Nada;
- Spliid, Charlotte B.;
- Khazamipour, Nastaran;
- Lo, Joey;
- Truong, Sarah;
- Collins, Colin;
- Hui, Desmond;
- Esfandnia, Shaghayegh;
- Adomat, Hans;
- Clausen, Thomas Mandel;
- Gustavsson, Tobias;
- Choudhary, Swati;
- Dagil, Robert;
- Corey, Eva;
- Wang, Yuzhuo;
- Chauchereau, Anne
Publication type:
Article
Author Correction: The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner.
Published in:
2022
By:
- Agerbæk, Mette Ø.;
- Bang-Christensen, Sara R.;
- Yang, Ming-Hsin;
- Clausen, Thomas M.;
- Pereira, Marina A.;
- Sharma, Shreya;
- Ditlev, Sisse B.;
- Nielsen, Morten A.;
- Choudhary, Swati;
- Gustavsson, Tobias;
- Sorensen, Poul H.;
- Meyer, Tim;
- Propper, David;
- Shamash, Jonathan;
- Theander, Thor G.;
- Aicher, Alexandra;
- Daugaard, Mads;
- Heeschen, Christopher;
- Salanti, Ali
Publication type:
Correction Notice
Optimization of rVAR2-Based Isolation of Cancer Cells in Blood for Building a Robust Assay for Clinical Detection of Circulating Tumor Cells.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 7, p. 2401, doi. 10.3390/ijms21072401
By:
- Sand, Nicolai T.;
- Petersen, Tobias B.;
- Bang-Christensen, Sara R.;
- Ahrens, Theresa D.;
- Løppke, Caroline;
- Jørgensen, Amalie M.;
- Gustavsson, Tobias;
- Choudhary, Swati;
- Theander, Thor G.;
- Salanti, Ali;
- Agerbæk, Mette Ø.
Publication type:
Article
Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23254-1
By:
- Wang, Kaituo;
- Dagil, Robert;
- Lavstsen, Thomas;
- Misra, Sandeep K.;
- Spliid, Charlotte B.;
- Wang, Yong;
- Gustavsson, Tobias;
- Sandoval, Daniel R.;
- Vidal-Calvo, Elena Ethel;
- Choudhary, Swati;
- Agerbaek, Mette Ø;
- Lindorff-Larsen, Kresten;
- Nielsen, Morten A.;
- Theander, Thor G.;
- Sharp, Joshua S.;
- Clausen, Thomas Mandel;
- Gourdon, Pontus;
- Salanti, Ali
Publication type:
Article
Efficient clearance of Aβ protofibrils in AβPP-transgenic mice treated with a brain-penetrating bifunctional antibody.
Published in:
Alzheimer's Research & Therapy, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13195-018-0377-8
By:
- Syvänen, Stina;
- Hultqvist, Greta;
- Gustavsson, Tobias;
- Gumucio, Astrid;
- Laudon, Hanna;
- Söderberg, Linda;
- Ingelsson, Martin;
- Lannfelt, Lars;
- Sehlin, Dag
Publication type:
Article
Somatic Mutations and Genetic Heterogeneity at the CDKN1B Locus in Small Intestinal Neuroendocrine Tumors.
Published in:
Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2015, v. 22, p. 1428, doi. 10.1245/s10434-014-4351-9
By:
- Crona, Joakim;
- Gustavsson, Tobias;
- Norlén, Olov;
- Edfeldt, Katarina;
- Åkerström, Tobias;
- Westin, Gunnar;
- Hellman, Per;
- Björklund, Peyman;
- Stålberg, Peter
Publication type:
Article
PET Imaging in Preclinical Anti-Aβ Drug Development.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1481, doi. 10.1007/s11095-022-03277-z
By:
- Syvänen, Stina;
- Meier, Silvio R.;
- Roshanbin, Sahar;
- Xiong, Mengfei;
- Faresjö, Rebecca;
- Gustavsson, Tobias;
- Bonvicini, Gillian;
- Schlein, Eva;
- Aguilar, Ximena;
- Julku, Ulrika;
- Eriksson, Jonas;
- Sehlin, Dag
Publication type:
Article
Biphasic Kinetic Behavior of E. coli WrbA, an FMN-Dependent NAD(P)H:Quinone Oxidoreductase.
Published in:
PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043902
By:
- Kishko, Iryna;
- Harish, Balasubramanian;
- Zayats, Vasilina;
- Reha, David;
- Tenner, Brian;
- Beri, Dhananjay;
- Gustavsson, Tobias;
- Ettrich, Rüdiger;
- Carey, Jannette;
- vertessy, Beata G.
Publication type:
Article
Detection of VAR2CSA-Captured Colorectal Cancer Cells from Blood Samples by Real-Time Reverse Transcription PCR.
Published in:
Cancers, 2021, v. 13, n. 23, p. 5881, doi. 10.3390/cancers13235881
By:
- Bang-Christensen, Sara R.;
- Katerov, Viatcheslav;
- Jørgensen, Amalie M.;
- Gustavsson, Tobias;
- Choudhary, Swati;
- Theander, Thor G.;
- Salanti, Ali;
- Allawi, Hatim T.;
- Agerbæk, Mette Ø.
Publication type:
Article
Oncofetal Chondroitin Sulfate Is a Highly Expressed Therapeutic Target in Non-Small Cell Lung Cancer.
Published in:
Cancers, 2021, v. 13, n. 17, p. 4489, doi. 10.3390/cancers13174489
By:
- Oo, Htoo Zarni;
- Lohinai, Zoltan;
- Khazamipour, Nastaran;
- Lo, Joey;
- Kumar, Gunjan;
- Pihl, Jessica;
- Adomat, Hans;
- Nabavi, Noushin;
- Behmanesh, Hakhamanesh;
- Zhai, Beibei;
- Dagil, Robert;
- Choudhary, Swati;
- Gustavsson, Tobias;
- Clausen, Thomas M.;
- Esko, Jeffrey D.;
- Allen, Jeffrey W.;
- Thompson, Michael A.;
- Tran, Nhan L.;
- Moldvay, Judit;
- Dome, Balazs
Publication type:
Article
Bacterial superglue enables easy development of efficient virus-like particle based vaccines.
Published in:
Journal of Nanobiotechnology, 2016, v. 14, p. 1, doi. 10.1186/s12951-016-0181-1
By:
- Thrane, Susan;
- Janitzek, Christoph M.;
- Matondo, Sungwa;
- Resende, Mafalda;
- Gustavsson, Tobias;
- de Jongh, Willem Adriaan;
- Clemmensen, Stine;
- Roeffen, Will;
- van de Vegte-Bolmer, Marga;
- van Gemert, Geert Jan;
- Sauerwein, Robert;
- Schiller, John T.;
- Nielsen, Morten A.;
- Theander, Thor G.;
- Salanti, Ali;
- Sander, Adam F.
Publication type:
Article
Brain delivery of biologics using a cross‐species reactive transferrin receptor 1 VNAR shuttle.
Published in:
FASEB Journal, 2020, v. 34, n. 10, p. 13272, doi. 10.1096/fj.202000610RR
By:
- Sehlin, Dag;
- Stocki, Pawel;
- Gustavsson, Tobias;
- Hultqvist, Greta;
- Walsh, Frank S.;
- Rutkowski, J. Lynn;
- Syvänen, Stina
Publication type:
Article
Molecular dissection of placental malaria protein VAR2CSA interaction with a chemo-enzymatically synthesized chondroitin sulfate library.
Published in:
Glycoconjugate Journal, 2016, v. 33, n. 6, p. 985, doi. 10.1007/s10719-016-9685-z
By:
- Sugiura, Nobuo;
- Clausen, Thomas;
- Shioiri, Tatsumasa;
- Gustavsson, Tobias;
- Watanabe, Hideto;
- Salanti, Ali
Publication type:
Article
Erratum to: Molecular dissection of placental malaria protein VAR2CSA interaction with a chemo-enzymatically synthesized chondroitin sulfate library.
Published in:
2016
By:
- Sugiura, Nobuo;
- Clausen, Thomas;
- Shioiri, Tatsumasa;
- Gustavsson, Tobias;
- Watanabe, Hideto;
- Salanti, Ali
Publication type:
Erratum
A simple method for detecting oncofetal chondroitin sulfate glycosaminoglycans in bladder cancer urine.
Published in:
Cell Death Discovery, 2020, v. 6, n. 1, p. 1, doi. 10.1038/s41420-020-00304-z
By:
- Clausen, Thomas Mandel;
- Kumar, Gunjan;
- Ibsen, Emilie K.;
- Ørum-Madsen, Maj S.;
- Hurtado-Coll, Antonio;
- Gustavsson, Tobias;
- Agerbæk, Mette Ø.;
- Gatto, Francesco;
- Todenhöfer, Tilman;
- Basso, Umberto;
- Knowles, Margaret A.;
- Sanchez-Carbayo, Marta;
- Salanti, Ali;
- Black, Peter C.;
- Daugaard, Mads
Publication type:
Article
Capture and Detection of Circulating Glioma Cells Using the Recombinant VAR2CSA Malaria Protein.
Published in:
Cells (2073-4409), 2019, v. 8, n. 9, p. 998, doi. 10.3390/cells8090998
By:
- Bang-Christensen, Sara R.;
- Pedersen, Rasmus S.;
- Pereira, Marina A.;
- Clausen, Thomas M.;
- Løppke, Caroline;
- Sand, Nicolai T.;
- Ahrens, Theresa D.;
- Jørgensen, Amalie M.;
- Lim, Yi Chieh;
- Goksøyr, Louise;
- Choudhary, Swati;
- Gustavsson, Tobias;
- Dagil, Robert;
- Daugaard, Mads;
- Sander, Adam F.;
- Torp, Mathias H.;
- Søgaard, Max;
- Theander, Thor G.;
- Østrup, Olga;
- Lassen, Ulrik
Publication type:
Article
The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05793-2
By:
- Agerbæk, Mette Ø.;
- Bang-Christensen, Sara R.;
- Yang, Ming-Hsin;
- Clausen, Thomas M.;
- Pereira, Marina A.;
- Sharma, Shreya;
- Ditlev, Sisse B.;
- Nielsen, Morten A.;
- Choudhary, Swati;
- Gustavsson, Tobias;
- Sorensen, Poul H.;
- Meyer, Tim;
- Propper, David;
- Shamash, Jonathan;
- Theander, Thor G.;
- Aicher, Alexandra;
- Daugaard, Mads;
- Heeschen, Christopher;
- Salanti, Ali
Publication type:
Article
Long-term effects of immunotherapy with a brain penetrating Aβ antibody in a mouse model of Alzheimer's disease.
Published in:
Alzheimer's Research & Therapy, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13195-023-01236-3
By:
- Gustavsson, Tobias;
- Metzendorf, Nicole G.;
- Wik, Elin;
- Roshanbin, Sahar;
- Julku, Ulrika;
- Chourlia, Aikaterini;
- Nilsson, Per;
- Andersson, Ken G.;
- Laudon, Hanna;
- Hultqvist, Greta;
- Syvänen, Stina;
- Sehlin, Dag
Publication type:
Article
Bispecific T cell-engager targeting oncofetal chondroitin sulfate induces complete tumor regression and protective immune memory in mice.
Published in:
Journal of Experimental & Clinical Cancer Research (17569966), 2023, v. 42, n. 1, p. 1, doi. 10.1186/s13046-023-02655-8
By:
- Skeltved, Nanna;
- Nordmaj, Mie A.;
- Berendtsen, Nicolai T.;
- Dagil, Robert;
- Stormer, Emilie M. R.;
- Al-Nakouzi, Nader;
- Jiang, Ke;
- Aicher, Alexandra;
- Heeschen, Christopher;
- Gustavsson, Tobias;
- Choudhary, Swati;
- Gögenur, Ismail;
- Christensen, Jan P.;
- Theander, Thor G.;
- Daugaard, Mads;
- Salanti, Ali;
- Nielsen, Morten A.
Publication type:
Article
An affinity chromatography and glycoproteomics workflow to profile the chondroitin sulfate proteoglycans that interact with malarial VAR2CSA in the placenta and in cancer.
Published in:
Glycobiology, 2020, v. 30, n. 12, p. 989, doi. 10.1093/glycob/cwaa039
By:
- Toledo, Alejandro Gómez;
- Pihl, Jessica;
- Spliid, Charlotte B;
- Persson, Andrea;
- Nilsson, Jonas;
- Pereira, Marina Ayres;
- Gustavsson, Tobias;
- Choudhary, Swati;
- Oo, Htoo Zarni;
- Black, Peter C;
- Daugaard, Mads;
- Esko, Jeffrey D;
- Larson, Göran;
- Salanti, Ali;
- Clausen, Thomas Mandel
Publication type:
Article
Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta.
Published in:
Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00258-x
By:
- Rofo, Fadi;
- Buijs, Jos;
- Falk, Ronny;
- Honek, Ken;
- Lannfelt, Lars;
- Lilja, Anna M.;
- Metzendorf, Nicole G.;
- Gustavsson, Tobias;
- Sehlin, Dag;
- Söderberg, Linda;
- Hultqvist, Greta
Publication type:
Article
Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta.
Published in:
Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00258-x
By:
- Rofo, Fadi;
- Buijs, Jos;
- Falk, Ronny;
- Honek, Ken;
- Lannfelt, Lars;
- Lilja, Anna M.;
- Metzendorf, Nicole G.;
- Gustavsson, Tobias;
- Sehlin, Dag;
- Söderberg, Linda;
- Hultqvist, Greta
Publication type:
Article
SPECT imaging of distribution and retention of a brain-penetrating bispecific amyloid-β antibody in a mouse model of Alzheimer's disease.
Published in:
Translational Neurodegeneration, 2020, v. 9, n. 1, p. N.PAG, doi. 10.1186/s40035-020-00214-1
By:
- Gustavsson, Tobias;
- Syvänen, Stina;
- O'Callaghan, Paul;
- Sehlin, Dag
Publication type:
Article
Enhanced neprilysin-mediated degradation of hippocampal Aβ42 with a somatostatin peptide that enters the brain.
Published in:
Theranostics, 2021, v. 11, n. 2, p. 789, doi. 10.7150/thno.50263
By:
- Rofo, Fadi;
- Yilmaz, Canan Ugur;
- Metzendorf, Nicole;
- Gustavsson, Tobias;
- Beretta, Chiara;
- Erlandsson, Anna;
- Dag Sehlin;
- Syvänen, Stina;
- Nilsson, Per;
- Hultqvist, Greta
Publication type:
Article
A cytochrome c fusion protein domain for convenient detection, quantification, and enhanced production of membrane proteins in Escherichia coli—Expression and characterization of cytochrome-tagged Complex I subunits.
Published in:
Protein Science: A Publication of the Protein Society, 2010, v. 19, n. 8, p. 1445, doi. 10.1002/pro.424
By:
- Gustavsson, Tobias;
- Trane, Maria;
- Moparthi, Vamsi K.;
- Miklovyte, Egle;
- Moparthi, Lavanya;
- Górecki, Kamil;
- Leiding, Thom;
- Årsköld, Sindra Peterson;
- Hägerhäll, Cecilia
Publication type:
Article
WrbA bridges bacterial flavodoxins and eukaryotic NAD(P)H:quinone oxidoreductases.
Published in:
Protein Science: A Publication of the Protein Society, 2007, v. 16, n. 10, p. 2301, doi. 10.1110/ps.073018907
By:
- Carey, Jannette;
- Brynda, Jiri;
- Wolfová, Julie;
- Grandori, Rita;
- Gustavsson, Tobias;
- Ettrich, Rüdiger;
- Smatanová, Ivana Kutá
Publication type:
Article
Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20251-8
By:
- Fougeroux, Cyrielle;
- Goksøyr, Louise;
- Idorn, Manja;
- Soroka, Vladislav;
- Myeni, Sebenzile K.;
- Dagil, Robert;
- Janitzek, Christoph M.;
- Søgaard, Max;
- Aves, Kara-Lee;
- Horsted, Emma W.;
- Erdoğan, Sayit Mahmut;
- Gustavsson, Tobias;
- Dorosz, Jerzy;
- Clemmensen, Stine;
- Fredsgaard, Laurits;
- Thrane, Susan;
- Vidal-Calvo, Elena E.;
- Khalifé, Paul;
- Hulen, Thomas M.;
- Choudhary, Swati
Publication type:
Article
Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA.
Published in:
PLoS Pathogens, 2022, v. 18, n. 11, p. 1, doi. 10.1371/journal.ppat.1010924
By:
- Raghavan, Sai Sundar Rajan;
- Dagil, Robert;
- Lopez-Perez, Mary;
- Conrad, Julian;
- Bassi, Maria Rosaria;
- Quintana, Maria del Pilar;
- Choudhary, Swati;
- Gustavsson, Tobias;
- Wang, Yong;
- Gourdon, Pontus;
- Ofori, Michael Fokuo;
- Christensen, Sebastian Boje;
- Minja, Daniel Thomas Remias;
- Schmiegelow, Christentze;
- Nielsen, Morten Agertoug;
- Barfod, Lea;
- Hviid, Lars;
- Salanti, Ali;
- Lavstsen, Thomas;
- Wang, Kaituo
Publication type:
Article

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