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- Title
(REH28) Correlates of Change in First Trial Exposures Across 2 Days of Protective Steps Among Those with Multiple Sclerosis.
- Authors
Van Liew, Charles; Dibble, Leland E.; Foreman, Bo; Peterson, Daniel S.
- Abstract
Background: Multiple sclerosis (MS) is a common, debilitating, neurogenerative disorder that causes myriad symptoms. Gait and balance dysfunctions are common and manifest early in the disease, increasing fall risk. In particular, the ability to quickly and effectively react to a loss of balance is worse in people with MS. Therefore, improving reactive balance among those with MS is desirable. However, for maximum ecological validity, improvements in reactive balance through training would be demonstrable upon first loss-of-balance exposure. Objectives: The aim of this study is to evaluate first trial changes in people with MS before and after 1 day of protective stepping practice. The study also seeks to identify clinical correlates of first trial changes to begin evaluating for whom such training may provide benefit. Methods: Fourteen people with MS underwent 2 consecutive days of support-surface perturbations using an instrumented treadmill. Protective stepping outcomes were step length, step latency, and margin of stability. The backward step performance on the first trials on days 1 and 2 were compared, and difference scores were evaluated for relationships with correlates based on theoretical considerations. Results: There were no significant changes in first trial performance after training. However, some clinical and cognitive characteristics, such as mini-BESTest performance, improvement from day 1 to day 2 on the Symbol-Digits Modality test, type of MS diagnosis, and falls history were related with the amount of change individuals experienced. Conclusions: Although preliminary, these findings provide evidence that those with more favorable disease states may see more robust first-trial improvements after perturbation training. Greater doses, larger and more homogeneous samples, or longer delay between training and reassessment may be needed to understand the existence and relevance of first trial changes.
- Subjects
CONFERENCES &; conventions; POSTURAL balance; ACCIDENTAL falls; GAIT in humans; MULTIPLE sclerosis
- Publication
International Journal of MS Care, 2020, Vol 22, Issue S2, p76
- ISSN
1537-2073
- Publication type
Article