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- Title
Support vector machine classification of brain metastasis and radiation necrosis based on texture analysis in MRI.
- Authors
Larroza, Andrés; Moratal, David; Paredes‐Sánchez, Alexandra; Soria‐Olivas, Emilio; Chust, María L.; Arribas, Leoncio A.; Arana, Estanislao
- Abstract
<bold>Purpose: </bold>To develop a classification model using texture features and support vector machine in contrast-enhanced T1-weighted images to differentiate between brain metastasis and radiation necrosis.<bold>Methods: </bold>Texture features were extracted from 115 lesions: 32 of them previously diagnosed as radiation necrosis, 23 as radiation-treated metastasis and 60 untreated metastases; including a total of 179 features derived from six texture analysis methods. A feature selection technique based on support vector machine was used to obtain a subset of features that provide optimal performance.<bold>Results: </bold>The highest classification accuracy evaluated over test sets was achieved with a subset of ten features when the untreated metastases were not considered; and with a subset of seven features when the classifier was trained with untreated metastases and tested on treated ones. Receiver operating characteristic curves provided area-under-the-curve (mean ± standard deviation) of 0.94 ± 0.07 in the first case, and 0.93 ± 0.02 in the second.<bold>Conclusion: </bold>High classification accuracy (AUC > 0.9) was obtained using texture features and a support vector machine classifier in an approach based on conventional MRI to differentiate between brain metastasis and radiation necrosis.
- Publication
Journal of Magnetic Resonance Imaging, 2015, Vol 42, Issue 5, p1362
- ISSN
1053-1807
- Publication type
journal article
- DOI
10.1002/jmri.24913