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- Title
Early Return to Intended Oncologic Therapy after implementation of an Enhanced Recovery After Surgery pathway for gastric cancer surgery.
- Authors
Garcia-Nebreda, Maria; Zorrilla-Vaca, Andrés; Ripollés-Melchor, Javier; Abad-Motos, Ane; Alvaro Cifuentes, Edurne; Abad-Gurumeta, Alfredo; Mena, Gabriel E.; Grant, Michael C.; Paseiro-Crespo, Gloria
- Abstract
Purpose: Time to initiation and completion of adjuvant therapy are critical to improve postoperative oncologic outcomes. This study aims to determine whether an Enhanced Recovery After Surgery (ERAS) pathway for gastric cancer surgery promotes early Return to Intended Oncologic Therapy (RIOT). Methods: This is a before-after intervention study including patients with gastric adenocarcinoma who underwent surgery from January 2016 to January 2021. Two periods were denoted based upon the implementation date of our institutional ERAS pathway (June 2018). Our primary outcome was time to RIOT after surgery. Hodges-Lehmann analysis was used to estimate median differences of non-parametric outcomes. Results: Seventy patients with gastric adenocarcinoma were included (35 in pre-ERAS period and 35 in post-ERAS period). Fourteen of the pre-ERAS and twenty-two patients of the post-ERAS period received adjuvant therapy. Time to RIOT was reduced in the post-ERAS period (median 39 days, IQR 31–49) by 12 days (95% CI 3–14 days, p = 0.01) compared to the pre-ERAS period (median 51 days, IQR 42–62). Length of hospital stay (LOS) was lower in the ERAS group (6 days, IQR 5–11 vs 10 days, IQR 8–13, p < 0.01). Conclusion: Our institutional ERAS pathway for gastric cancer surgery was associated with earlier RIOT and shorter LOS.
- Subjects
ENHANCED recovery after surgery protocol; ONCOLOGIC surgery; STOMACH cancer; LENGTH of stay in hospitals
- Publication
Langenbeck's Archives of Surgery, 2022, Vol 407, Issue 6, p2293
- ISSN
1435-2443
- Publication type
Article
- DOI
10.1007/s00423-022-02515-7