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- Title
Long-Term Outcomes of Treatment-Resistant Heroin Addicts with and without DSM-IV Axis 1 Psychiatric Comorbidity (Dual Diagnosis).
- Authors
Maremmani, Icro; Pacini, Matteo; Lubrano, Sonia; Perugi, Giulio; Tagliamonte, Alessandro; Pani, Pier Paolo; Gerra, Gilberto; Shinderman, Marc
- Abstract
Objective: The aim of this study was to compare the long-term outcomes of treatment-resistant heroin addicts with and without DSM-IV axis I psychiatric comorbidity (dual diagnosis). Method: 129 heroin addicts who also met criteria for treatment resistance, 66 with one or more DSM-IV axis I psychiatric diagnosis (DD patients), and 63 without DSM-IV axis I psychiatric comorbidity (NDD patients) were monitored prospectively (6 years on average, min. 1, max. 9) along a methadone maintenance treatment program (MMTP). Results: The rates for survival-in-treatment were about 50% for NDD patients and about 70% for DD patients. After 4 years of treatment onwards, such rates tended to become stable. DD patients showed better outcome measures than NDD patients. A significantly higher methadone dose was needed to have DD patients stabilized. Conclusions: Contrary to expectations, treatment-resistant patients with psychiatric comorbidity showed a better long-term outcome than treatment-resistant patients without psychiatric comorbidity. Copyright © 2008 S. Karger AG, Basel
- Subjects
TREATMENT of heroin abuse; DRUG abuse; SUBSTANCE abuse; HEROIN; PSYCHIATRY; ADDICTIONS
- Publication
European Addiction Research, 2008, Vol 14, Issue 3, p134
- ISSN
1022-6877
- Publication type
Article
- DOI
10.1159/000130417