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- Title
Tubulointerstitial nephritis and Fanconi syndrome in a patient with primary Sjögren's syndrome accompanied by antimitochondrial antibodies: A case report and review of the literature.
- Authors
Takako Saeki; Akihiro Nakajima; Tomoyuki Ito; Takuma Takata; Naofumi Imai; Kazuhiro Yoshita; Hideyuki Kabasawa; Hajime Yamazaki; Ichiei Narita
- Abstract
We describe a 53-year-old woman with primary Sjögren's syndrome and tubulointerstitial nephritis showing distal renal tubular acidosis and Fanconi syndrome. The patient showed high serum IgM levels and positivity for antimitochondrial antibodies, although her liver function was in normal range. According to our literature review, 75% of patients with tubulointerstitial nephritis who were positive for antimitochondrial antibodies showed Fanconi syndrome, suggesting that these antibodies may directly be associated with the pathophysiology of Fanconi syndrome.
- Subjects
INTERSTITIAL nephritis; FANCONI syndrome; PATHOLOGICAL physiology; SJOGREN'S syndrome; IMMUNOGLOBULINS
- Publication
Modern Rheumatology, 2018, Vol 28, Issue 5, p897
- ISSN
1439-7595
- Publication type
Article
- DOI
10.3109/14397595.2016.1174422