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- Title
Two Different Days of Transcranial Doppler Examinations Should Be Performed for Detection of Right-to-Left Shunt in Acute Stroke Patients.
- Authors
Aoki, Junya; Kimura, Kazumi; Iguchi, Yasuyuki; Sakai, Kenichiro; Sakamoto, Yuki; Terasawa, Yuka; Shibazaki, Kensaku; Kobayashi, Kazuto
- Abstract
ABSTRACT BACKGROUND We investigated how many contrast-transcranial Doppler (c-TCD) examinations should be performed on different days in patients with acute stroke. METHODS Consecutive acute stroke patients within 24 hours of onset were enrolled. Presence of RLS was examined using c-TCD examinations on days 1, 7, and 14. Each c-TCD examination used one test without Valsalva maneuver (VM) and three tests with VM. Patients were diagnosed with RLS when TCD detected ≥1 microembolic signal on ≥1 c-TCD examination on any of the days 1, 7, or 14. RESULTS One hundred seventy patients (105 men [62%]; median age, 74 [IQR, 66-81] years) were enrolled. RLS was diagnosed in 45 patients (26%). RLS was identified on day 1 in 30 patients (18%), on day 7 in 28 patients (16%), and on day 14 in 23 patients (14%; P= .143). Detection rate of RLS by combining day 1 and 7 examinations was significantly higher than that of day 1 alone (25% vs 18%, P < .001). However, the rate did not increase when results of day 14 were added (25% vs 26%, P= .250). CONCLUSIONS c-TCD examinations should be performed on at least two different days to assess the prevalence of RLS.
- Subjects
STROKE patients; VALSALVA'S maneuver; EMBOLISMS; TRANSCRANIAL Doppler ultrasonography; DIAGNOSIS
- Publication
Journal of Neuroimaging, 2013, Vol 23, Issue 2, p175
- ISSN
1051-2284
- Publication type
Article
- DOI
10.1111/j.1552-6569.2011.00660.x