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- Title
Keratitis, ichthyosis and deafness syndrome with development of multiple hair follicle tumours.
- Authors
Kim, K-H.; Piao, J-S. Kim, Y-J.; Kim, Y-C.; Shur, K-B.; Lee, J-H.; Park, J-K.
- Abstract
We report multiple occurrences of various kinds of tumours that originate from hair follicles in a patient diagnosed with KID (keratitis, ichthyosis, deafness) syndrome. These tumours are diagnosed as: (i) trichilemmal cysts in early lesions; (ii) proliferating trichilemmal tumours in moderate duration lesions; and (iii) malignant proliferating trichilemmal tumours in advanced lesions that are thought to progress from benign trichilemmal lesions. This three-step process raises the hypothesis of a multihit model that could account for the frequent development of tumours in KID patients.
- Subjects
HAIR follicles; KERATITIS; ICHTHYOSIS; TUMORS
- Publication
British Journal of Dermatology, 2002, Vol 147, Issue 1, p139
- ISSN
0007-0963
- Publication type
Article
- DOI
10.1046/j.1365-2133.2002.04724.x