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- Title
Severe atypical molluscum contagiosum infection in an immunocompromised host.
- Authors
Cotton, D. W. K.; Cooper, C.; Barrett, D. F.; Leppard, B. J.
- Abstract
A case of severe molluscum contagiosum in a patient with treated thymoma is described. This unusual complication of immunosuppression is discussed and the literature on the subject reviewed. The immunosuppressed state, whether due to primary diseases themselves or to their therapy, may be associated with florid manifestations or increased frequency of several viral skin infections, most notably those due to herpes, warts and measles viruses.1 Molluscum contagiosum is a benign, often self-limiting skin disorder resulting from infection by a pox virus. We report a case in which a severe, refractory, atypical eruption, histologically confirmed to be due to molluscum contagiosum, was associated with profound immunosuppression in a patient with a malignant thymoma who had been treated with radiotherapy, chemotherapy and rabbit anti-human thymocyte globulin. This association between severe molluscum infection and immunosuppression, which has rarely been reported, is of clinical importance as the condition presents a difficult diagnostic and therapeutic problem in the immunocompromised host.
- Subjects
SKIN infections; POXVIRUS diseases; SKIN inflammation; VIRUS diseases; IMMUNODEFICIENCY; MEASLES virus; DERMATOLOGY
- Publication
British Journal of Dermatology, 1987, Vol 116, Issue 6, p871
- ISSN
0007-0963
- Publication type
Article
- DOI
10.1111/j.1365-2133.1987.tb04908.x