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- Title
How We Treat Fever and Hypotension in Pediatric Hematopoietic Cell Transplant Patients.
- Authors
Zinter, Matt S.; Dvorak, Christopher C.; Auletta, Jeffery J.
- Abstract
Pediatric allogeneic hematopoietic cell transplant (HCT) survival is limited by the development of post-transplant infections. In this overview, we discuss a clinical approach to the prompt recognition and treatment of fever and hypotension in pediatric HCT patients. Special attention is paid to individualized hemodynamic resuscitation, thorough diagnostic testing, novel anti-pathogen therapies, and the multimodal support required for recovery. We present three case vignettes that illustrate the complexities of post-HCT sepsis and highlight best practices that contribute to optimal transplant survival in children.
- Subjects
HYPOTENSION; TRANSPLANTATION of organs, tissues, etc.; FEVER; VIGNETTES; SEPSIS
- Publication
Frontiers in Oncology, 2020, Vol 10, pN.PAG
- ISSN
2234-943X
- Publication type
Article
- DOI
10.3389/fonc.2020.581447