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- Title
Distinguishing Zika and Dengue Viruses through Simple Clinical Assessment, Singapore.
- Authors
Yan, Gabriel; Siew Seen Ho; Oon, Jolene; Smitasin, Nares; Long Pang; Cook, Alex R.; Tambyah, Paul A.; Fisher, Dale; Bagdasarian, Natasha; Chai, Louis Yi Ann; Mar Soe Win; Ho, Hanley J.; Wong, Joshua G. X.; Lye, David C.; Yee Sin Leo; Chow, Angela; Ai Leng Khoo; Chun Kiat Lee; Yan, Benedict; Jureen, Roland
- Abstract
Dengue virus and Zika virus coexist in tropical regions in Asia where healthcare resources are limited; differentiating the 2 viruses is challenging. We showed in a case-control discovery cohort, and replicated in a validation cohort, that the diagnostic indices of conjunctivitis, platelet count, and monocyte count reliably distinguished between these viruses.
- Subjects
SINGAPORE; DENGUE viruses; ZIKA virus; CONJUNCTIVITIS; LOGISTIC regression analysis; CENTERS for Disease Control &; Prevention (U.S.); DIAGNOSIS of fever; ANIMAL experimentation; COMPARATIVE studies; DENGUE; DIFFERENTIAL diagnosis; FEVER; FLAVIVIRUSES; LONGITUDINAL method; RESEARCH methodology; MEDICAL cooperation; MOSQUITOES; MYALGIA; RESEARCH; EVALUATION research; CASE-control method; RECEIVER operating characteristic curves; LEUKOCYTE count; PLATELET count; VIRAL conjunctivitis; INFECTIOUS disease transmission
- Publication
Emerging Infectious Diseases, 2018, Vol 24, Issue 8, p1565
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid2408.171883