We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Genetic Characterization of Foot-and-Mouth Disease Viruses, Ethiopia, 1981-2007.
- Authors
Ayelet, Gelagay; Mahapatra, Mana; Gelaye, Esayas; Egziabher, Berhe G.; Rufeal, Tesfaye; Sahle, Mesfin; Ferris, Nigel P.; Wadsworth, Jemma; Hutchings, Geoffrey H.; Knowles, Nick J.
- Abstract
Foot-and-mouth disease (FMD) is endemic to sub-Saharan Africa. To further understand its complex epidemiology, which involves multiple virus serotypes and host species, we characterized the viruses recovered from FMD outbreaks in Ethiopia during 1981-2007. We detected 5 of the 7 FMDV serotypes (O, A, C, Southern African Territories [SAT] 1, and SAT 2). Serotype O predominated, followed by serotype A; type C was not recognized after 1983. Phylogenetic analysis of virus protein 1 sequences indicated emergence of a new topotype within serotype O, East Africa 4. In 2007, serotype SAT 1 was detected in Ethiopia and formed a new distinct topotype (IX), and serotype SAT 2 reappeared after an apparent gap of 16 years. The diversity of viruses highlights the role of this region as a reservoir for FMD virus, and their continuing emergence in Ethiopia will greatly affect spread and consequent control strategy of the disease on this continent.
- Subjects
ETHIOPIA; FOOT &; mouth disease; VIRUSES; VETERINARY virology; EPIDEMIOLOGY; PICORNAVIRUS infections
- Publication
Emerging Infectious Diseases, 2009, Vol 15, Issue 9, p1409
- ISSN
1080-6040
- Publication type
Article
- DOI
10.3201/eid1509.090091