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- Title
Onset of progressive phase is an age-dependent clinical milestone in multiple sclerosis.
- Authors
Tutuncu, Melih; Tang, Junger; Zeid, Nuhad Abou; Kale, Nilufer; Crusan, Daniel J; Atkinson, Elizabeth J; Siva, Aksel; Pittock, Sean J; Pirko, Istvan; Keegan, B Mark; Lucchinetti, Claudia F; Noseworthy, John H; Rodriguez, Moses; Weinshenker, Brian G; Kantarci, Orhun H
- Abstract
The article presents a study which investigates the onset of progressive disease course of multiple sclerosis (MS) in relation to the patient's age. The study assessed population-based and clinical-based MS cohort as well as age-of-progression-onset (t-test) and time to Expanded Disability Status Scale of 6 (EDSS6). The study found that onset of progression is more dependent on age than the presence or duration of a relapsing disease course in MS.
- Subjects
DISEASE progression; DISEASE relapse; MULTIPLE sclerosis; AGE; COHORT analysis; T-test (Statistics); PATIENTS
- Publication
Multiple Sclerosis Journal, 2013, Vol 19, Issue 2, p188
- ISSN
1352-4585
- Publication type
Article
- DOI
10.1177/1352458512451510