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- Title
Preparation of temperature-sensitive poly( N-isopropylacrylamide)/β-cyclodextrin-grafted polyethylenimine hydrogels for drug delivery.
- Authors
Zhang, Jian-Tao; Xue, Ya-Nan; Gao, Fa-Zhi; Huang, Shi-Wen; Zhuo, Ren-Xi
- Abstract
The article presents a study on the development of temperature-sensitive poly(N-isopropylacrylamide) (PNIPAAm)/β-cyclodextrin-grafred polyethylenimine hydrogels for drug delivery. For the study, researchers purified NIPAAm through recrystallization from a mixed solvent of benzene and n-hexane. They found that the semi-interpenetrating network hydrogels resulted a higher swelling ratio at room temperature and manifester a more aggressive shrinking kinetics when the temperature was increased.
- Subjects
CYCLODEXTRINS; BENZENE; AROMATIC compounds; HEXANE; ALKANES
- Publication
Journal of Applied Polymer Science, 2008, Vol 108, Issue 5, p3031
- ISSN
0021-8995
- Publication type
Article
- DOI
10.1002/app.27931