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- Title
Incidence of Malignancies in HIV-Infected Patients and Prognostic Role of Current CD4 Cell Count: Evidence from a Large Italian Cohort Study.
- Authors
Prosperi, M. C. F.; Cozzi-Lepri, A.; Castagna, A.; Mussini, C.; Murri, R.; Giacometti, A.; Torti, C.; Costantini, A.; Narciso, P.; Ghinelli, F.; Antinori, A.; Monforte, A. d'Arminio
- Abstract
The incidence of and predictors of acquired immunodeficiency syndrome-defining malignancies (ADMs) and non- ADM (NADMs) were evaluated in a large Italian cohort. The incidence of ADM and NADM was 5.0 cases per 1000 personyears of follow-up (95% confidence interval, 4.3-5.8 cases per 1000 person-years of follow-up) and 2.4 cases per 1000 person-years of follow-up (95% confidence interval, 1.9-3.1 cases per 1000 person-years of follow-up), respectively. Lower current CD4 cell count was an independent predictor of developing malignancies, with the association being stronger for ADM than for NADM.
- Subjects
ITALY; HIV-positive persons; AIDS research; CONFIDENCE intervals; IMMUNOLOGICAL deficiency syndromes; CD4 antigen; COHORT analysis; DIAGNOSIS
- Publication
Clinical Infectious Diseases, 2010, Vol 50, Issue 9, p1316
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1086/651688