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- Title
Immunological and Biochemical Correlates of Adjunctive Dexamethasone in Vietnamese Adults with Bacterial Meningitis.
- Authors
Nguyen Thi Hoang Mai; Trung Vu Tuan; Wolbers, Marcel; Dang Minh Hoang; Tran Vu Thieu Nga; Tran Thi Hong Chau; Ly Van Chuong; Dinh Xuan Sinh; Ho Dang Trung Nghia; Nguyen Duy Phong; Nguyen Hoan Phu; To Song Diep; Hoang Thi Thanh Hang; Nguyen van Vinh Chau; Farrar, Jeremy; Schultsz, Constance; Tran Tinh Hien; Simmons, Cameron P.
- Abstract
Adjunctive treatment to improve outcome from bacterial meningitis has centered on dexamethasone. Among Vietnamese patients with bacterial meningitis, cerebrospinal fluid (CSF) opening pressure and CSF:plasma glucose ratios were significantly improved and levels of CSF cytokines interleukin (IL)-6, IL-8, and IL-10 and were all statistically significantly lower after treatment in patients who were randomized to dexamethasone, compared with levels in patients who received placebo.
- Subjects
MENINGITIS treatment; DEXAMETHASONE; CEREBROSPINAL fluid; BACTERIAL diseases; CYTOKINES; INTERLEUKIN-6; INTERLEUKIN-8; INTERLEUKIN-10; VIETNAMESE people; MEDICAL research
- Publication
Clinical Infectious Diseases, 2009, Vol 49, Issue 9, p1387
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1086/630207