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Increased CSF-decorin predicts brain pathological changes driven by Alzheimer's Aβ amyloidosis.
Published in:
Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01398-5
By:
- Jiang, Richeng;
- Smailovic, Una;
- Haytural, Hazal;
- Tijms, Betty M.;
- Li, Hao;
- Haret, Robert Mihai;
- Shevchenko, Ganna;
- Chen, Gefei;
- Abelein, Axel;
- Gobom, Johan;
- Frykman, Susanne;
- Sekiguchi, Misaki;
- Fujioka, Ryo;
- Watamura, Naoto;
- Sasaguri, Hiroki;
- Nyström, Sofie;
- Hammarström, Per;
- Saido, Takaomi C.;
- Jelic, Vesna;
- Syvänen, Stina
Publication type:
Article
Neuroligin-1 in brain and CSF of neurodegenerative disorders: investigation for synaptic biomarkers.
Published in:
Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01119-4
By:
- Camporesi, Elena;
- Lashley, Tammaryn;
- Gobom, Johan;
- Lantero-Rodriguez, Juan;
- Hansson, Oskar;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Becker, Bruno
Publication type:
Article
Cerebrospinal fluid biomarker panel for synaptic dysfunction in a broad spectrum of neurodegenerative diseases.
Published in:
Brain: A Journal of Neurology, 2024, v. 147, n. 7, p. 2414, doi. 10.1093/brain/awae032
By:
- Nilsson, Johanna;
- Binette, Alexa Pichet;
- Palmqvist, Sebastian;
- Brum, Wagner S;
- Janelidze, Shorena;
- Ashton, Nicholas J;
- Spotorno, Nicola;
- Stomrud, Erik;
- Gobom, Johan;
- Zetterberg, Henrik;
- Brinkmalm, Ann;
- Blennow, Kaj;
- Hansson, Oskar
Publication type:
Article
Pathophysiological subtypes of Alzheimer's disease based on cerebrospinal fluid proteomics.
Published in:
2020
By:
- Tijms, Betty M;
- Gobom, Johan;
- Reus, Lianne;
- Jansen, Iris;
- Hong, Shengjun;
- Dobricic, Valerija;
- Kilpert, Fabian;
- Kate, Mara ten;
- Barkhof, Frederik;
- Tsolaki, Magda;
- Verhey, Frans R J;
- Popp, Julius;
- Martinez-Lage, Pablo;
- Vandenberghe, Rik;
- Lleó, Alberto;
- Molinuevo, José Luís;
- Engelborghs, Sebastiaan;
- Bertram, Lars;
- Lovestone, Simon;
- Streffer, Johannes
Publication type:
journal article
CSF proteomic profiles of neurodegeneration biomarkers in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 9, p. 6205, doi. 10.1002/alz.14103
By:
- Delvenne, Aurore;
- Gobom, Johan;
- Schindler, Suzanne E.;
- Kate, Mara ten;
- Reus, Lianne M.;
- Dobricic, Valerija;
- Tijms, Betty M.;
- Benzinger, Tammie L. S.;
- Cruchaga, Carlos;
- Teunissen, Charlotte E.;
- Ramakers, Inez;
- Martinez‐Lage, Pablo;
- Tainta, Mikel;
- Vandenberghe, Rik;
- Schaeverbeke, Jolien;
- Engelborghs, Sebastiaan;
- Roeck, Ellen De;
- Popp, Julius;
- Peyratout, Gwendoline;
- Tsolaki, Magda
Publication type:
Article
Post‐GWAS multiomic functional investigation of the TNIP1 locus in Alzheimer's disease highlights a potential role for GPX3.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 7, p. 5044, doi. 10.1002/alz.13848
By:
- Panyard, Daniel J.;
- Reus, Lianne M.;
- Ali, Muhammad;
- Liu, Jihua;
- Deming, Yuetiva K.;
- Lu, Qiongshi;
- Kollmorgen, Gwendlyn;
- Carboni, Margherita;
- Wild, Norbert;
- Visser, Pieter J.;
- Bertram, Lars;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Gobom, Johan;
- Western, Dan;
- Sung, Yun Ju;
- Carlsson, Cynthia M.;
- Johnson, Sterling C.;
- Asthana, Sanjay;
- Cruchaga, Carlos
Publication type:
Article
Clinical proteomic analysis across the Alzheimer's disease continuum.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082938
By:
- Weiner, Sophia;
- Sauer, Mathias;
- Ashton, Nicholas J.;
- Benedet, Andrea Lessa;
- Rosa‐Neto, Pedro;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Gobom, Johan
Publication type:
Article
Optimal combination of CSF phosphorylated‐tau forms to predict Alzheimer's disease pathological burden as measured by PET.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082746
By:
- Collij, Lyduine E.;
- Gobom, Johan;
- Janelidze, Shorena;
- Ossenkoppele, Rik;
- Smith, Ruben;
- Strandberg, Olof;
- Stomrud, Erik;
- Palmqvist, Sebastian;
- Mattsson‐Carlgren, Niklas;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Hansson, Oskar
Publication type:
Article
Blood proteomics to identify AD CSF molecular subtypes.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079584
By:
- Tijms, Betty M.;
- Teunissen, Charlotte E.;
- Gobom, Johan;
- Shi, Liu;
- Zetterberg, Henrik;
- Lovestone, Simon;
- Visser, Pieter Jelle;
- Blennow, Kaj
Publication type:
Article
Profiling amyloid‐β peptides as diagnostic biomarkers for cerebral amyloid angiopathy.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076080
By:
- van den Berg, Emma;
- de Kort, Anna M.;
- Kersten, Iris;
- Brinkmalm, Gunnar;
- Johansson, Kjell;
- Marques, Tainá M.;
- Jäkel, Lieke;
- Gobom, Johan;
- Stoops, Erik;
- Portelius, Erik;
- Gkanatsiou, Eleni;
- Abdo, Wilson F.;
- Rasing, Ingeborg;
- Voigt, Sabine;
- Koemans, Emma A.;
- Kaushik, Kanishk;
- Warren, Andrew D.;
- Greenberg, Steven M.;
- Terwindt, Gisela M.;
- Wermer, Marieke J.H.
Publication type:
Article
Strategy for absolute quantification of phospho‐Tau epitopes in cerebrospinal fluid by mass spectrometry.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079543
By:
- Gomes, Bárbara Fernandes;
- Sauer, Mathias;
- Weiner, Sophia;
- Andreasson, Ulf;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Gobom, Johan
Publication type:
Article
Investigation of the choroid plexus implication in Alzheimer's disease pathophysiology using human proteomics and mouse transcriptomics.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079553
By:
- Delvenne, Aurore;
- Vandendriessche, Charysse;
- Gobom, Johan;
- Fagan, Anne M.;
- Verhey, Frans R.J.;
- Zetterberg, Henrik;
- Visser, Pieter Jelle;
- Vandenbroucke, Roosmarijn E;
- Vos, Stephanie J. B.
Publication type:
Article
SCRN1: A cerebrospinal fluid biomarker correlating with tau in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 4609, doi. 10.1002/alz.13042
By:
- Weiner, Sophia;
- Sauer, Mathias;
- Brinkmalm, Gunnar;
- Constantinescu, Julius;
- Constantinescu, Radu;
- Gomes, Bárbara Fernandes;
- Becker, Bruno;
- Nellgård, Bengt;
- Dalla, Keti;
- Galasko, Douglas;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Gobom, Johan
Publication type:
Article
Protein disulfide isomerases as CSF biomarkers for the neuronal response to tau pathology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 8, p. 3563, doi. 10.1002/alz.12978
By:
- Wolzak, Kimberly;
- Vermunt, Lisa;
- Campo, Marta del;
- Jorge‐Oliva, Marta;
- van Ziel, Anna Maria;
- Li, Ka Wan;
- Smit, August B.;
- Chen‐Ploktkin, Alice;
- Irwin, David J.;
- Lemstra, Afina W.;
- Pijnenburg, Yolande;
- van der Flier, Wiesje;
- Zetterberg, Henrik;
- Gobom, Johan;
- Blennow, Kaj;
- Visser, Pieter Jelle;
- Teunissen, Charlotte E.;
- Tijms, Betty M.;
- Scheper, Wiep
Publication type:
Article
Identifying Protein Quantitative Trait Loci in the Cerebrospinal Fluid Proteome.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.059964
By:
- Reus, Lianne M.;
- Teunissen, Charlotte E.;
- Gobom, Johan;
- Vos, Stephanie J. B.;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Bertram, Lars;
- Visser, Pieter Jelle;
- Tijms, Betty M.
Publication type:
Article
Cerebrospinal fluid biomarker panel of synaptic dysfunction in Alzheimer's disease and other neurodegenerative disorders.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 5, p. 1775, doi. 10.1002/alz.12809
By:
- Nilsson, Johanna;
- Cousins, Katheryn A.Q.;
- Gobom, Johan;
- Portelius, Erik;
- Chen‐Plotkin, Alice;
- Shaw, Leslie M.;
- Grossman, Murray;
- Irwin, David J.;
- Trojanowski, John Q.;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Brinkmalm, Ann
Publication type:
Article
Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non‐Alzheimer's disease pathophysiology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 3, p. 807, doi. 10.1002/alz.12713
By:
- Delvenne, Aurore;
- Gobom, Johan;
- Tijms, Betty;
- Bos, Isabelle;
- Reus, Lianne M.;
- Dobricic, Valerija;
- Kate, Mara ten;
- Verhey, Frans;
- Ramakers, Inez;
- Scheltens, Philip;
- Teunissen, Charlotte E.;
- Vandenberghe, Rik;
- Schaeverbeke, Jolien;
- Gabel, Silvy;
- Popp, Julius;
- Peyratout, Gwendoline;
- Martinez‐Lage, Pablo;
- Tainta, Mikel;
- Tsolaki, Magda;
- Freund‐Levi, Yvonne
Publication type:
Article
Simultaneous Mass Spectrometric quantification of multiple p‐tau species in plasma – findings along the Alzheimer´s disease continuum.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.069305
By:
- Montoliu‐Gaya, Laia;
- Benedet, Andréa Lessa;
- Brum, Wagner Scheeren;
- Vrillon, Agathe;
- Ashton, Nicholas J.;
- Rodriguez, Juan Lantero;
- Brinkmalm, Gunnar;
- Nilsson, Johanna;
- Karikari, Thomas K;
- Kern, Silke;
- Zetterberg, Henrik;
- Paquet, Claire;
- Rosa‐Neto, Pedro;
- Gobom, Johan;
- Blennow, Kaj
Publication type:
Article
Derivation of cut‐offs for plasma neurofilament light in clinical routine using healthy subjects aged between 5‐90.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.065181
By:
- Simrén, Joel;
- Gobom, Johan;
- Andreasson, Ulf;
- Suárez‐Calvet, Marc;
- Depypere, Herman;
- Nyberg, Lars;
- Borroni, Barbara;
- Zetterberg, Henrik;
- Blennow, Kaj
Publication type:
Article
GMNC risk alleles in individuals with Alzheimer's disease are associated with cerebrospinal fluid concentrations of proteins involved in neuronal plasticity and blood brain barrier function.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.065570
By:
- Visser, Pieter Jelle;
- Reus, Lianne M.;
- Gobom, Johan;
- Teunissen, Charlotte E.;
- Bertram, Lars;
- Zetterberg, Henrik;
- Tijms, Betty M.
Publication type:
Article
Multi‐modal Analysis and Modeling of Human Neurodegenerative Disease to Reveal Disease Mechanisms and Biomarkers.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.061905
By:
- Marsh, Samuel E;
- Murphy, Sarah;
- Kamath, Tushar;
- Gazestani, Vahid;
- Therrien, Martine;
- Dolan, Michael John;
- Jereb, Sasa;
- Reyes, Miguel;
- Gobom, Johan;
- Clish, Clary;
- Hacohen, Nir;
- Zetterberg, Henrik;
- Leinonen, Ville;
- Macosko, Evan;
- Stevens, Beth
Publication type:
Article
CSF Proteome Changes Depend on APOE Genotype in Prodromal AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.061043
By:
- Vromen, Eleonora M.;
- Wesenhagen, Kirsten E. J.;
- van der Kant, Rik;
- Gobom, Johan;
- Scheltens, Philip;
- Teunissen, Charlotte E.;
- Dobricic, Valerija;
- Bertram, Lars;
- Zetterberg, Henrik;
- Visser, Pieter Jelle;
- Tijms, Betty M.
Publication type:
Article
Choroid plexus volume is associated with levels of CSF proteins predominantly expressed by the choroid plexus in non‐demented individuals with AD pathophysiology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.067517
By:
- Delvenne, Aurore;
- Tijms, Betty M.;
- Gobom, Johan;
- Redolfi, Alberto;
- Barkhof, Frederik;
- Zetterberg, Henrik;
- Visser, Pieter Jelle;
- Vos, Stephanie J. B.
Publication type:
Article
Mass spectrometric measurement of six site‐specific tau phosphorylations in CSF and blood of Alzheimer's disease patients.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.055985
By:
- Montoliu‐Gaya, Laia;
- Ashton, Nicholas J.;
- Benedet, Andréa Lessa;
- Rodriguez, Juan Lantero;
- Brinkmalm, Gunnar;
- Karikari, Thomas K.;
- Kern, Silke;
- Rosa‐Neto, Pedro;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Gobom, Johan
Publication type:
Article
A novel antibody‐free mass spectrometry panel of CSF biomarkers for synaptic dysfunction.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054818
By:
- Nilsson, Johanna;
- Cousins, Katheryn A.Q.;
- Gobom, Johan;
- Portelius, Erik;
- Chen‐Plotkin, Alice;
- Shaw, Les M.;
- Grossman, Murray;
- Trojanowski, John Q.;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Brinkmalm, Ann
Publication type:
Article
Decorin is an early CSF biomarker of Alzheimer's Aβ amyloidosis.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054474
By:
- Jiang, Richeng;
- Smailovic, Una;
- Haytural, Hazal;
- Haret, Robert Mihai;
- Shevchenko, Ganna;
- Tijms, Betty;
- Gobom, Johan;
- Abelein, Axel;
- Johansson, Jan;
- Zetterberg, Henrik;
- Winblad, Bengt;
- Frykman, Susanne;
- Jelic, Vesna;
- Bergquist, Jonas;
- Visser, Pieter Jelle;
- Nilsson, Per
Publication type:
Article
Immune protein levels in cerebrospinal fluid: Associations with memory scores across the AD spectrum.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.055451
By:
- Wesenhagen, Kirsten E. J.;
- Teunissen, Charlotte E.;
- Gobom, Johan;
- Vos, Stephanie J. B.;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Scheltens, Philip;
- Tijms, Betty M.;
- Visser, Pieter Jelle
Publication type:
Article
Cerebrospinal fluid proteomic profiling of individuals with prodromal Alzheimer's disease classified using two different neurodegenerative biomarkers (N) in A/T/N classification.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.053030
By:
- Delvenne, Aurore;
- Gobom, Johan;
- Tijms, Betty M.;
- Verhey, Frans R.J.;
- Barkhof, Frederik;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Visser, Pieter Jelle;
- Vos, Stephanie J. B.
Publication type:
Article
Alzheimer's disease genetic risk variants show brain cell type‐specific associations with protein levels in cerebrospinal fluid.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.049531
By:
- Reus, Lianne M.;
- Van Der Lee, Sven J;
- Teunissen, Charlotte E.;
- Gobom, Johan;
- Vos, Stephanie J. B.;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Bertram, Lars;
- Visser, Pieter Jelle;
- Tijms, Betty M.
Publication type:
Article
CSF proteomic profiling of mild cognitive impairment individuals with suspected non‐Alzheimer's disease pathophysiology: Developing topics.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.047247
By:
- Delvenne, Aurore;
- Gobom, Johan;
- Tijms, Betty M;
- Bos, Isabelle;
- Verhey, Frans RJ;
- Ramakers, Inez HGB;
- Scheltens, Philip;
- Teunissen, Charlotte E;
- Vandenberghe, Rik;
- Gabel, Silvy;
- Popp, Julius;
- Peyratout, Gwendoline;
- Martinez‐Lage, Pablo;
- Tainta, Mikel;
- Tsolaki, Magda;
- Freund‐Levi, Yvonne;
- Lovestone, Simon;
- Streffer, Johannes;
- Blennow, Kaj;
- Zetterberg, Henrik
Publication type:
Article
Synaptic proteins relate to memory scores in preclinical Alzheimer's disease and cognitively healthy controls depending on amyloid: Molecular and cell biology/synaptic disruption.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046102
By:
- Wesenhagen, Kirsten E.J.;
- Visser, Pieter Jelle;
- Gobom, Johan;
- Bos, Isabelle;
- Vos, Stephanie J.B.;
- Martinez‐Lage, Pablo;
- Tainta, Mikel;
- Popp, Julius;
- Peyratout, Gwendoline;
- Tsolaki, Magda;
- Vandenberghe, Rik;
- Freund‐Levi, Yvonne;
- Verhey, Frans R.J.;
- Lovestone, Simon;
- Streffer, Johannes;
- Blennow, Kaj;
- Scheltens, Philip;
- Teunissen, Charlotte E.;
- Zetterberg, Henrik;
- Tijms, Betty M.
Publication type:
Article
A novel proteomics assay allows parallel quantitation of a panel of synaptic proteins in human cerebrospinal fluid: Biomarkers (non‐neuroimaging) / novel biomarkers.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042578
By:
- Nilsson, Johanna;
- Gobom, Johan;
- Brinkmalm, Gunnar;
- Zetterberg, Henrik;
- Brinkmalm, Ann;
- Blennow, Kaj
Publication type:
Article
Ultra‐performance liquid chromatography‐tandem mass spectrometry method for analysis of tau in human cerebrospinal fluid without the need of immunocapture: Biomarkers (non‐neuroimaging) / Method development and/or quality control.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040373
By:
- Korecka, Magdalena;
- Leinenbach, Andreas;
- Gobom, Johan;
- Delatour, Vincent;
- Becher, Francois;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Pannee, Josef;
- Hofving, Katarina;
- Shaw, Leslie M.
Publication type:
Article
P4‐525: ASSOCIATION OF CSF TAU WITH HYPERPLASTICITY IN ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1515, doi. 10.1016/j.jalz.2019.08.072
By:
- Visser, Pieter Jelle;
- Gobom, Johan;
- Reus, Lianne M.;
- Jansen, Iris E.;
- Tsolaki, Magda;
- Verhey, Frans R.J.;
- Popp, Julius;
- Martinez-Lage, Pablo;
- Vandenberghe, Rik;
- Lleó, Alberto;
- Molinuevo, Jose Luis;
- Engelborghs, Sebastiaan;
- Lovestone, Simon;
- Streffer, Johannes;
- Vos, Stephanie J.B.;
- Bos, Isabelle;
- Bertram, Lars;
- Posthuma, Danielle;
- Smit, August B.;
- Blennow, Kaj
Publication type:
Article
P2‐242: PATHOPHYSIOLOGICAL SUBTYPES OF ALZHEIMER'S DISEASE BASED ON CEREBROSPINAL FLUID PROTEOMICS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P675, doi. 10.1016/j.jalz.2019.06.2649
By:
- Tijms, Betty M.;
- Gobom, Johan;
- Blennow, Kaj;
- Tsolaki, Magda;
- Verhey, Frans R.J.;
- Popp, Julius;
- Martinez-Lage, Pablo;
- Vandenberghe, Rik;
- Poesen, Koen;
- Lleó, Alberto;
- Engelborghs, Sebastiaan;
- Bertram, Lars;
- Molinuevo, Jose Luis;
- Lovestone, Simon;
- Streffer, Johannes;
- Vos, Stephanie J.B.;
- Bos, Isabelle;
- Teunissen, Charlotte E.;
- Scheltens, Philip;
- Zetterberg, Henrik
Publication type:
Article
P1‐266: COMPARISON OF A FULLY AUTOMATED BEAD‐BASED SYSTEM WITH AN ENZYME‐LINKED IMMUNOSORBENT ASSAY AND AN ELECTROCHEMILUMINESCENT ASSAY FOR MEASUREMENT OF CORE AD BIOMARKERS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P341, doi. 10.1016/j.jalz.2019.06.821
By:
- Clarin, Marcus;
- Gobom, Johan;
- Vandijck, Manu;
- Huyck, Els;
- Le Bastard, Nathalie;
- Andreasson, Ulf;
- Zetterberg, Henrik;
- Blennow, Kaj
Publication type:
Article
O3‐14‐04: THE PROTEIN‐TO‐PEPTIDE RATIO IMPROVES THE PERFORMANCE OF MICROTUBULE‐ASSOCIATED PROTEIN TAU IN CSF AS AN ALZHEIMER BIOMARKER.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1060, doi. 10.1016/j.jalz.2018.06.2852
By:
- Hansson, Karl;
- Dahlén, Rahil;
- Hansson, Oskar;
- Pernevik, Elin;
- Paterson, Ross W.;
- Schott, Jonathan M.;
- Magdalinou, Nadia;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Gobom, Johan
Publication type:
Article
Novel cerebrospinal fluid biomarkers correlating with shunt responsiveness in patients with idiopathic normal pressure hydrocephalus.
Published in:
Fluids & Barriers of the CNS, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12987-023-00440-5
By:
- Weiner, Sophia;
- Junkkari, Antti;
- Sauer, Mathias;
- Luikku, Antti;
- Rauramaa, Tuomas;
- Kokkola, Tarja;
- Herukka, Sanna-Kaisa;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Leinonen, Ville;
- Gobom, Johan
Publication type:
Article
APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer's disease.
Published in:
Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13195-020-00628-z
By:
- Konijnenberg, Elles;
- Tijms, Betty M.;
- Gobom, Johan;
- Dobricic, Valerija;
- Bos, Isabelle;
- Vos, Stephanie;
- Tsolaki, Magda;
- Verhey, Frans;
- Popp, Julius;
- Martinez-Lage, Pablo;
- Vandenberghe, Rik;
- Lleó, Alberto;
- Frölich, Lutz;
- Lovestone, Simon;
- Streffer, Johannes;
- Bertram, Lars;
- Blennow, Kaj;
- Teunissen, Charlotte E.;
- Veerhuis, Robert;
- Smit, August B.
Publication type:
Article
N-TERMINAL FRAGMENT OF TAU: ASSAY DEVELOPMENT WITH IN-HOUSE CLEAVAGE-SPECIFIC ANTIBODY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P964, doi. 10.1016/j.jalz.2017.06.1294
By:
- Cicognola, Claudia;
- Brinkmalm, Gunnar;
- Portelius, Erik;
- Gobom, Johan;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Höglund, Kina
Publication type:
Article
NOVEL CSF FRAGMENTS OF TAU: CANDIDATE BIOMARKERS OF ALZHEIMER’S DISEASE AND TAUOPATHIES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P706, doi. 10.1016/j.jalz.2017.06.898
By:
- Höglund, Kina;
- Cicognola, Claudia;
- Portelius, Erik;
- Brinkmalm, Gunnar;
- Zheng, Zhentao;
- Hansson, Oskar;
- Zetterberg, Henrik;
- Ye, Keqiang;
- Blennow, Kaj;
- Gobom, Johan
Publication type:
Article
PROTEOMIC CHANGES IN ZEBRAFISH LACKING THE AMYLOID PRECURSOR HOMOLOG, APPB, USING A HIGH-THROUGHPUT DIFFERENTIAL PROTEOMIC APPROACH.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1439, doi. 10.1016/j.jalz.2017.06.2253
By:
- Abramsson, Alexandra;
- Banote, Rakesh;
- Gobom, Johan;
- Zetterberg, Henrik
Publication type:
Article
PLEIOTROPHIN, A NEW BIOMARKER FOR AD, IDENTIFIED USING A NOVEL STRATEGY IN CLINICAL PROTEOMICS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P960, doi. 10.1016/j.jalz.2017.06.1285
By:
- Skillback, Tobias;
- Mattsson, Niklas;
- Hansson, Karl;
- Mirgorodskaya, Ekaterina;
- van der Flier, Wiesje M.;
- Scheltens, Philip;
- Duits, Floor;
- Hansson, Oskar;
- Teunissen, Charlotte E.;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Gobom, Johan
Publication type:
Article
LUMIPULSE® G TOTAL TAU: KEY PERFORMANCES OF A FULLY AUTOMATED CHEMILUMINESCENT IMMUNOASSAY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1512, doi. 10.1016/j.jalz.2017.07.628
By:
- Vandijck, Manu;
- Dauwe, Martine;
- Huyck, Els;
- Le Bastard, Nathalie;
- Lawson, John;
- Traynham, Christopher;
- Vucetic, Zivjena;
- Gobom, Johan;
- Blennow, Kaj;
- Jannes, Geert;
- Kostanjevecki, Vesna
Publication type:
Article
Round robin test on quantification of amyloid-β 1–42 in cerebrospinal fluid by mass spectrometry.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, n. 1, p. 55, doi. 10.1016/j.jalz.2015.06.1890
By:
- Pannee, Josef;
- Gobom, Johan;
- Shaw, Leslie M.;
- Korecka, Magdalena;
- Chambers, Erin E.;
- Lame, Mary;
- Jenkins, Rand;
- Mylott, William;
- Carrillo, Maria C.;
- Zegers, Ingrid;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Portelius, Erik
Publication type:
Article
International round robin on SRM triple quad mass spectrometric analysis of aβ42 in cerebrospinal fluid.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, p. P797, doi. 10.1016/j.jalz.2014.05.1555
By:
- Pannee, Josef;
- Portelius, Erik;
- Gobom, Johan;
- Shaw, Leslie;
- Korecka, Magdalena;
- Chambers, Erin E.;
- Lame, Mary;
- Jenkins, Rand G.;
- Mylott, William;
- Zegers, Ingrid;
- Carrillo, Maria;
- Zetterberg, Henrik;
- Blennow, Kaj
Publication type:
Article
Cerebrospinal fluid biomarker standardization efforts
Published in:
2012
By:
- Mattsson, Niklas;
- Andreasson, Ulf;
- Bjerke, Maria;
- Gobom, Johan;
- Pannee, Josef;
- Persson, Staffan;
- Portelius, Erik;
- Zetterberg, Henrik;
- Blennow, Kaj
Publication type:
Abstract
An LC-MS/MS-based method for quantification of beta-amyloid-1-38, beta-amyloid-1-40 and beta-amyloid-1-42 in the cerebrospinal fluid of Alzheimer's patients and healthy controls
Published in:
2012
By:
- Pannee, Josef;
- Gobom, Johan;
- Opperman, Madalina;
- Atkins, Alan;
- Zetterberg, Henrik;
- Minthon, Lennart;
- Blennow, Kaj;
- Hansson, Oskar;
- Portelius, Erik
Publication type:
Abstract
Amyloid-related biomarkers for BACE1 inhibition in cell models of Alzheimer's disease
Published in:
2010
By:
- Olsson, Maria;
- Portelius, Erik;
- Sjölander, Annica;
- Andreasson, Ulf;
- Hölttä, Mikko;
- Brinkmalm, Gunnar;
- Gobom, Johan;
- Brinkmalm, Ann;
- Blennow, Kaj;
- Zetterberg, Henrik
Publication type:
Abstract
An enzyme activity as a potential biomarker for Alzheimer's disease
Published in:
2010
By:
- Andreasson, Ulf;
- Bjerke, Maria;
- Gobom, Johan;
- Hansson, Oskar;
- Johansson, Per;
- Svensson, Johan;
- Zetterberg, Henrik;
- Blennow, Kaj
Publication type:
Abstract

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