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- Title
Alcohol and the Pancreas: Clinical Associations and Histopathology of Minimal Pancreatic Inflammation.
- Authors
Noronha, M.; Salgadinho, A.; De Almeida, M. J. Ferreira; Dreiling, D. A.; Bordalo, O.
- Abstract
Fat accumulation within pancreatic acinar cells was observed by examination in patients consuming more than 80 gm./day of ethanol. Ultrastructural changes within the cell are described in these alcoholics without clinical pancreatitis, changes which are similar to those seen in the hepatocytes of alcoholics. The mechanisms which induce these ultrastructural changes and accumulation of fat in the pancreatic acinar cell are not apparent at present. A toxic metabolic mechanism is an attractive hypothesis for these effects.
- Subjects
PANCREATIC acinar cells; PHYSIOLOGICAL effects of alcohol; PANCREATITIS; HISTOPATHOLOGY; PANCREATIC diseases
- Publication
American Journal of Gastroenterology (Springer Nature), 1982, Vol 77, Issue 10, p827
- ISSN
0002-9270
- Publication type
Article