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- Title
Animal models - Mimicking the pain of trigeminal neuralgia.
- Authors
Gupta, Sonu; Bansal, Ravinder; Singh Sodhi, Surender; Brar, Gursimrat
- Abstract
Trigeminal neuralgia (TN) is an episodic facial pain which feels like an electric shock of unilateral origin. This neuropathic disorder is an intensely stressful to bear for patient and impacts the quality of life. Most of the cases of TN arise when the root of fifth cranial nerve, i.e., trigeminal nerve is compressed after a few millimeters of its entry into the pons. This article describes various animal models and the role of biomarkers to study the underlying mechanisms of neuropathic pain in animal models as well as different modes of management of TN.
- Subjects
TRIGEMINAL neuralgia; ANIMAL models in research; FACIAL pain; TRIGEMINAL nerve; NEURALGIA
- Publication
Indian Journal of Pharmacology, 2022, Vol 54, Issue 2, p138
- ISSN
0253-7613
- Publication type
Article
- DOI
10.4103/ijp.ijp_296_19