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The orally bioavailable met inhibitor PF-2341066 inhibits osteosarcoma growth and osteolysis/matrix production in a xenograft model.
Published in:
Journal of Bone & Mineral Research, 2011, v. 26, n. 6, p. 1283, doi. 10.1002/jbmr.336
By:
- Sampson, Erik R.;
- Martin, Brad A.;
- Morris, Aimee E.;
- Chao Xie;
- Schwarz, Edward M.;
- O'Keefe, Regis J.;
- Rosier, Randy N.
Publication type:
Article
Synergistic response to oncogenic mutations defines gene class critical to cancer phenotype.
Published in:
Nature, 2008, v. 453, n. 7198, p. 1112, doi. 10.1038/nature06973
By:
- McMurray, Helene R.;
- Sampson, Erik R.;
- Compitello, George;
- Kinsey, Conan;
- Newman, Laurel;
- Smith, Bradley;
- Chen, Shaw-Ree;
- Klebanov, Lev;
- Salzman, Peter;
- Yakovlev, Andrei;
- Land, Hartmut
Publication type:
Article
MMP13 is a critical target gene during the progression of osteoarthritis.
Published in:
Arthritis Research & Therapy, 2013, v. 15, n. 1, p. 1, doi. 10.1186/ar4133
By:
- Wang, Meina;
- Sampson, Erik R.;
- Hongting Jin;
- Jia Li;
- .Ke, Qiao H;
- Im, Hee-Jeong;
- Chen, Di
Publication type:
Article
High-fat diet accelerates progression of osteoarthritis after meniscal/ligamentous injury.
Published in:
Arthritis Research & Therapy, 2011, v. 13, n. 6, p. 3529, doi. 10.1186/ar3529
By:
- Mooney, Robert A.;
- Sampson, Erik R.;
- Lerea, Jaclyn;
- Rosier, Randy N.;
- Zuscik, Michael J.
Publication type:
Article
Ski inhibits TGF-β/phospho-Smad3 signaling and accelerates hypertrophic differentiation in chondrocytes.
Published in:
Journal of Cellular Biochemistry, 2012, v. 113, n. 6, p. 2156, doi. 10.1002/jcb.24089
By:
- Kim, Kyung-Ok;
- Sampson, Erik R.;
- Maynard, Robert D.;
- O'Keefe, Regis J.;
- Chen, Di;
- Drissi, Hicham;
- Rosier, Randy N.;
- Hilton, Matthew J.;
- Zuscik, Michael J.
Publication type:
Article
HLA-Restriction of Human Treg Cells Is Not Required for Therapeutic Efficacy of Low-Dose IL-2 in Humanized Mice.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.630204
By:
- Tyagi, Rajeev K.;
- Jacobse, Justin;
- Li, Jing;
- Allaman, Margret M.;
- Otipoby, Kevin L.;
- Sampson, Erik R.;
- Wilson, Keith T.;
- Goettel, Jeremy A.
Publication type:
Article
Teriparatide as a Chondroregenerative Therapy for Injury-Induced Osteoarthritis.
Published in:
Science Translational Medicine, 2011, v. 3, n. 101, p. 1, doi. 10.1126/scitranslmed.3002214
By:
- Sampson, Erik R.;
- Hilton, Matthew J.;
- Ye Tian;
- Di Chen;
- Schwarz, Edward M.;
- Mooney, Robert A.;
- Bukata, Susan V.;
- O'Keefe, Regis J.;
- Awad, Hani;
- Puzas, J. Edward;
- Rosier, Randy N.;
- Zuscik, Michael J.
Publication type:
Article
ABBV-105, a selective and irreversible inhibitor of Bruton's tyrosine kinase, is efficacious in multiple preclinical models of inflammation.
Published in:
Modern Rheumatology, 2019, v. 29, n. 3, p. 510, doi. 10.1080/14397595.2018.1484269
By:
- Goess, Christian;
- Harris, Christopher M.;
- Murdock, Sara;
- McCarthy, Richard W.;
- Sampson, Erik;
- Twomey, Rachel;
- Mathieu, Suzanne;
- Mario, Regina;
- Perham, Matthew;
- Goedken, Eric R.;
- Long, Andrew J.
Publication type:
Article
Syk Inhibition Induces Platelet Dependent Peri-islet Hemorrhage in the Rat Pancreas.
Published in:
Toxicologic Pathology, 2016, v. 44, n. 7, p. 998, doi. 10.1177/0192623316654015
By:
- Long, Andrew J.;
- Sampson, Erik;
- McCarthy, Richard W.;
- Harris, Christopher M.;
- Barnard, Marc;
- Shi, Dan;
- Conlon, Donna;
- Caldwell, Robert;
- Honor, David;
- Wishart, Neil;
- Hoemann, Michael;
- Duggan, Lori;
- Fritz, Douglas;
- Stedman, Christopher;
- O’Connor, Elizabeth;
- Mikaelian, Igor;
- Schwartz, Annette
Publication type:
Article
Lead induces an osteoarthritis-like phenotype in articular chondrocytes through disruption of TGF-β signaling.
Published in:
Journal of Orthopaedic Research, 2012, v. 30, n. 11, p. 1760, doi. 10.1002/jor.22117
By:
- Holz, Jonathan D.;
- Beier, Eric;
- Sheu, Tzong-Jen;
- Ubayawardena, Resika;
- Wang, Meina;
- Sampson, Erik R.;
- Rosier, Randy N.;
- Zuscik, Michael;
- Puzas, J. Edward
Publication type:
Article
Unique angiogenic and vasculogenic properties of renal cell carcinoma in a xenograft model of bone metastasis are associated with high levels of vegf-a and decreased ang-1 expression.
Published in:
Journal of Orthopaedic Research, 2012, v. 30, n. 2, p. 325, doi. 10.1002/jor.21500
By:
- Xie, Chao;
- Schwarz, Edward M.;
- Sampson, Erik R.;
- Dhillon, Robinder S.;
- Li, Dan;
- O'Keefe, Regis J.;
- Tyler, Wakenda
Publication type:
Article
Establishment of an index with increased sensitivity for assessing murine arthritis.
Published in:
Journal of Orthopaedic Research, 2011, v. 29, n. 8, p. 1145, doi. 10.1002/jor.21368
By:
- Sampson, Erik R.;
- Beck, Christopher A.;
- Ketz, John;
- Canary, Krista L.;
- Hilton, Matthew J.;
- Awad, Hani;
- Schwarz, Edward M.;
- Di Chen;
- O'Keefe, Regis J.;
- Rosier, Randy N.;
- Zuscik, Michael J.
Publication type:
Article
The histone deacetylase inhibitor vorinostat selectively sensitizes fibrosarcoma cells to chemotherapy.
Published in:
Journal of Orthopaedic Research, 2011, v. 29, n. 4, p. 623, doi. 10.1002/jor.21274
By:
- Sampson, Erik R.;
- Amin, Vinit;
- Schwarz, Edward M.;
- O'Keefe, Regis J.;
- Rosie, Randy N.
Publication type:
Article

Found: 13