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- Title
先天性膈疝患儿手术后近期肺功能观察 及相关因素分析.
- Authors
张奕; 马立霜; 曹玲; 张悅; 宋欣; 王莹; 刘超; 魏延栋
- Abstract
Objective To analyze the recent postoperative lung function of children with congenital diaphragmatic hernia (CDH), and explore the risk factors affecting lung function to guide the clinical follow-up. Methods The clinical data of children undergoing CDH repair and lung function examination from April 2016 to January 2021 was retrospectively reviewed. According to the result of lung function examination, they were di vided into normal group and abnormal group (including obstructive ventilation dysfunction, restricted ventilation dysfunction and mixed ventilation dysfunction) and compared the intergroup differences. The mean time of lung function test was 1.6 months (11 days - 18 months) after repair. Results of the 32 cases of CDH children. 5 (15.6%) had normal pulmonary function while other 27 (84.4%) had adnormal pulmonary function. Subject to the result of the first lung function examination, 20(62.5%) cases showed obstructive ventilation dysfunction,3(9.4%) cases showed restricted ventilation dysfunction, and 4(12.5%) cases showed mixed ventilation dysfunction. Both normal and abnormal groups had statistical differences in pulmonary artery hypertension (2/5 US. 23/27,P<0.05), oxygen duration[ (12. 22 +6.09) d vs. (21.48±9. 12)d, P<0.05]. The oxygen use at 30 days after birth had no significant statistical significance. The mean of prenatal diagnosis time of abnormal group was significantly smaller than normal group, but there was no significant statistical difference [ (30.67 ± 3.51) w vs. (26.77 ±4.38) w.P>0.05]. Conclusion Attention should be paid to CDH children who have different degrees of lung dysfunction early after surgery. Obstructive ventilation dysfunction is more common after CDH repair. Arterial hypertension and oxygen use duration may be risk factors for lung dysfunction. It is speculated that the prenatal diagnosis time may affect the lung function of children with CDH.
- Publication
Journal of Clinical Pediatric Surgery, 2022, Issue 3, p236
- ISSN
1671-6353
- Publication type
Article
- DOI
10.3760/cma.j.cn101785-202107030-007