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- Title
The Apparent Impunity of the Basal Ganglia to Therapeutic Lesioning: Clinical and Scientific Lessons.
- Authors
Monje, Mariana H. G.; Mañez-Miró, Jorge U.; Obeso, José A.
- Abstract
This article explores the impact of therapeutic lesioning of the basal ganglia on patients with movement disorders. While lesioning can have clinical benefits, such as reducing akinesia and tremors, it can also lead to deficits in motor performance and impairments in learning new tasks. Non-motor symptoms like impulsivity and speech disturbances can also arise. The document emphasizes the role of the basal ganglia in motor function and discusses the effects of lesioning or blocking basal ganglia activity. It suggests that interrupting abnormal basal ganglia activity is preferable to allowing faulty signaling to disrupt the motor system. Additionally, the document provides a list of references to scientific articles on Parkinson's disease and the basal ganglia, offering valuable insights for researchers and healthcare professionals in the field.
- Subjects
BASAL ganglia; MOVEMENT disorders; VERBAL behavior testing; IMPUNITY; INFORMED consent (Medical law); NEURAL circuitry; DEEP brain stimulation
- Publication
Movement Disorders Clinical Practice, 2023, Vol 10, Issue 1, pS42
- ISSN
2330-1619
- Publication type
Article
- DOI
10.1002/mdc3.13787