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- Title
Polyneuropathy developing after infliximab therapy in a patient with recalcitrant pyoderma gangrenosum.
- Authors
Singer, Ralfi; Örken, Cihat; Güngör, Şule; Çopur, Mehmet; Kızıltaç, Utkan; Kızıltaç, Kübra; Göncü, Emek Kocatürk; Erhan, Selma Şengiz
- Abstract
The use of tumor necrosis factor-alpha (TNF-α) inhibitors has increased tremendously during the recent years. Neurological side effects associated with TNF-α inhibitors are rarely encountered, but these side effects may result in serious clinical problems. Treatment with TNF-α inhibitors is associated with demyelinating syndromes which can affect both the central and peripheral nervous systems. Short-term follow-up indicates relatively good outcomes, sometimes after just treatment discontinuation, although corticosteroids or intravenous immunoglobulin may be necessary to reverse the conditions in some cases. Here, we present a case of motor neuropathy developing after treatment with infliximab in a patient with recalcitrant pyoderma gangrenosum.
- Subjects
POLYNEUROPATHIES; DEMYELINATION; PYODERMA gangrenosum; BIOPSY; TACROLIMUS; HYPERBARIC oxygenation; LEG ulcers; TRIAMCINOLONE; TUMOR necrosis factors; INFLIXIMAB; TREATMENT effectiveness; CHEMICAL inhibitors; DIAGNOSIS; DISEASE risk factors
- Publication
Turkish Archives of Dermatology & Venerology / Turkderm, 2019, Vol 53, Issue 1, p24
- ISSN
1019-214X
- Publication type
Article
- DOI
10.4274/turkderm.galenos.2018.70437