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- Title
Oral lichenoid lesions in two snuff users with contact allergy to carvone.
- Authors
Adwa, Usamah; Antelmi, Annarita; Sukakul, Thanisorn; Dahlin, Jakob; Bruze, Magnus; Svedman, Cecilia
- Abstract
Background: Contact allergy to the mint‐tasting flavour carvone has been observed in patients with oral lichenoid lesions (OLL). Mint‐flavoured products such as toothpaste frequently contain carvone. Snuff is a smokeless tobacco product that is chewed or placed in the mouth rather than smoked. In Sweden, the use of snuff and its flavoured versions is extremely common. Objectives: To investigate whether the consumption of mint‐flavoured snuff is associated with contact allergy to carvone and subsequently plays a role in the aetiology of OLL. Methods: Regarding the two patients, patch testing with snuff pouches was performed. High‐performance liquid chromatography and gas chromatography–mass spectrometry analysis were used for identification of carvone in different snuff samples. Results: Two patients with OLL were contacted allergic to carvone when patch tested. Both were using mint‐flavoured snuffs several hours a day for many years. One patient was contacted allergic to the snuff pouch tested as is. Carvone was detected in the snuff samples of both patients. Conclusions: The patients were recommended to avoid the use of mint‐flavoured snuffs, toothpaste and foodstuffs. At follow‐up 3 months later, the patients had a dramatic clinical improvement of the OLL and oral symptoms. Exposure to mint‐flavoured snuffs can be overlooked as a possible aggravating/provoking factor in OLL.
- Publication
Contact Dermatitis (01051873), 2024, Vol 90, Issue 1, p74
- ISSN
0105-1873
- Publication type
Article
- DOI
10.1111/cod.14448