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Genetic analysis of chemoresistance in primary murine lymphomas.
- Published in:
- Nature Medicine, 2000, v. 6, n. 9, p. 1029, doi. 10.1038/79542
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- Publication type:
- Article
Reversal of human cellular senescence: roles of the p53 and p16 pathways.
- Published in:
- EMBO Journal, 2003, v. 22, n. 16, p. 4212, doi. 10.1093/emboj/cdg417
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- Publication type:
- Article
Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model.
- Published in:
- 2008
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- Publication type:
- journal article
The retinoblastoma tumor suppressor modifies the therapeutic response of breast cancer.
- Published in:
- 2007
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- Publication type:
- journal article
A conserved element in Myc that negatively regulates its proapoptotic activity.
- Published in:
- EMBO Reports, 2005, v. 6, n. 2, p. 177, doi. 10.1038/sj.embor.7400333
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- Publication type:
- Article
TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions.
- Published in:
- eLife, 2016, p. 1, doi. 10.7554/eLife.17929
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- Publication type:
- Article
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.
- Published in:
- Nature Biotechnology, 2022, v. 40, n. 6, p. 862, doi. 10.1038/s41587-021-01172-3
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- Publication type:
- Article
Optimized base editors enable efficient editing in cells, organoids and mice.
- Published in:
- Nature Biotechnology, 2018, v. 36, n. 10, p. 888, doi. 10.1038/nbt.4194
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- Publication type:
- Article
Optimized base editors enable efficient editing in cells, organoids and mice.
- Published in:
- Nature Biotechnology, 2018, v. 36, n. 9, p. 888, doi. 10.1038/nbt.4194
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- Publication type:
- Article
Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer.
- Published in:
- Nature Biotechnology, 2017, v. 35, n. 6, p. 577, doi. 10.1038/nbt.3837
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- Publication type:
- Article
Prediction of potent shRNAs with a sequential classification algorithm.
- Published in:
- Nature Biotechnology, 2017, v. 35, n. 4, p. 350, doi. 10.1038/nbt.3807
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- Publication type:
- Article
Inducible in vivo genome editing with CRISPR-Cas9.
- Published in:
- Nature Biotechnology, 2015, v. 33, n. 4, p. 390, doi. 10.1038/nbt.3155
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- Publication type:
- Article
Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi.
- Published in:
- Nature Biotechnology, 2011, v. 29, n. 1, p. 79, doi. 10.1038/nbt.1720
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- Publication type:
- Article
Towards patient-based cancer therapeutics.
- Published in:
- 2010
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- Publication type:
- Opinion
A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.
- Published in:
- Nature Biotechnology, 2009, v. 27, n. 3, p. 264, doi. 10.1038/nbt.1526
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- Publication type:
- Article
In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer.
- Published in:
- Nature Medicine, 2014, v. 20, n. 10, p. 1138, doi. 10.1038/nm.3679
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- Publication type:
- Article
Senescence comes of age.
- Published in:
- Nature Medicine, 2005, v. 11, n. 9, p. 920, doi. 10.1038/nm0905-920
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- Publication type:
- Article
Apoptosis and therapy.
- Published in:
- Journal of Pathology, 1999, v. 187, n. 1, p. 127, doi. 10.1002/(SICI)1096-9896(199901)187:1<127::AID-PATH251>3.0.CO;2-T
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- Publication type:
- Article
Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis.
- Published in:
- Nature Genetics, 2015, v. 47, n. 5, p. 539, doi. 10.1038/ng.3251
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- Publication type:
- Article
Tissue-specific and reversible RNA interference in transgenic mice.
- Published in:
- Nature Genetics, 2007, v. 39, n. 7, p. 914, doi. 10.1038/ng2045
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- Publication type:
- Article
Probing tumor phenotypes using stable and regulated synthetic microRNA precursors.
- Published in:
- Nature Genetics, 2005, v. 37, n. 11, p. 1289, doi. 10.1038/ng1651
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- Publication type:
- Article
An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo.
- Published in:
- Nature Genetics, 2003, v. 33, n. 3, p. 396, doi. 10.1038/ng1091
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- Publication type:
- Article
Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23.
- Published in:
- Nature Genetics, 2002, v. 31, n. 2, p. 133, doi. 10.1038/ng888
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- Publication type:
- Article
p53 and p73: seeing double?
- Published in:
- Nature Genetics, 2000, v. 26, n. 4, p. 391, doi. 10.1038/82497
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- Publication type:
- Article
The gene encoding the splicing factor SF2/ASF is a proto-oncogene.
- Published in:
- Nature Structural & Molecular Biology, 2007, v. 14, n. 3, p. 185, doi. 10.1038/nsmb1209
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- Publication type:
- Article
P53 is required for radiation-induced apoptosis in mouse thymocytes.
- Published in:
- Nature, 1993, v. 362, n. 6423, p. 847, doi. 10.1038/362847a0
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- Publication type:
- Article
scKINETICS: inference of regulatory velocity with single-cell transcriptomics data.
- Published in:
- Bioinformatics, 2023, v. 39, p. i394, doi. 10.1093/bioinformatics/btad267
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- Publication type:
- Article
Reciprocal Interaction of Wnt and RXR-α Pathways in Hepatocyte Development and Hepatocellular Carcinoma.
- Published in:
- PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0118480
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- Publication type:
- Article
Reversible Suppression of Cyclooxygenase 2 (COX-2) Expression <i>In Vivo</i> by Inducible RNA Interference.
- Published in:
- PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0101263
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- Publication type:
- Article
Conditional Reverse Tet-Transactivator Mouse Strains for the Efficient Induction of TRE-Regulated Transgenes in Mice.
- Published in:
- PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0095236
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- Publication type:
- Article
Two Distinct Categories of Focal Deletions in Cancer Genomes.
- Published in:
- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0066264
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- Publication type:
- Article
Variability of Inducible Expression across the Hematopoietic System of Tetracycline Transactivator Transgenic Mice.
- Published in:
- PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054009
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- Publication type:
- Article
Apoptosis and chemoresistance in transgenic cancer models.
- Published in:
- Journal of Molecular Medicine, 2002, v. 80, n. 3, p. 137, doi. 10.1007/s00109-001-0293-3
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- Publication type:
- Article
Recurrent chromosomal aberrations in INK4a/ARF defective primary lymphomas predict drug responses in vivo.
- Published in:
- Oncogene, 2005, v. 24, n. 26, p. 4174, doi. 10.1038/sj.onc.1208600
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- Publication type:
- Article
Control of apoptosis by p53.
- Published in:
- Oncogene, 2003, v. 22, n. 56, p. 9030, doi. 10.1038/sj.onc.1207116
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- Publication type:
- Article
Apoptosis and melanoma chemoresistance.
- Published in:
- Oncogene, 2003, v. 22, n. 20, p. 3138, doi. 10.1038/sj.onc.1206454
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- Publication type:
- Article
Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12291-6
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- Publication type:
- Article
Senescent cells spread the word: non-cell autonomous propagation of cellular senescence.
- Published in:
- EMBO Journal, 2013, v. 32, n. 14, p. 1975, doi. 10.1038/emboj.2013.139
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- Publication type:
- Article
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas.
- Published in:
- 2011
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- Publication type:
- Correction Notice
HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase.
- Published in:
- Nature, 2010, v. 465, n. 7298, p. 577, doi. 10.1038/nature09141
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- Publication type:
- Article
Stem cells: The promises and perils of p53.
- Published in:
- Nature, 2009, v. 460, n. 7259, p. 1085, doi. 10.1038/4601085a
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- Publication type:
- Article
A microRNA component of the p53 tumour suppressor network.
- Published in:
- Nature, 2007, v. 447, n. 7148, p. 1130, doi. 10.1038/nature05939
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- Publication type:
- Article
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas.
- Published in:
- 2007
- By:
- Publication type:
- Letter
Role of genomic instability and p53 in AID-induced c-myc–Igh translocations.
- Published in:
- Nature, 2006, v. 440, n. 7080, p. 105, doi. 10.1038/nature04495
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- Publication type:
- Article
Suppression of eukaryotic initiation factor 4E prevents chemotherapy-induced alopecia.
- Published in:
- BMC Pharmacology & Toxicology, 2013, v. 14, n. 1, p. 1, doi. 10.1186/2050-6511-14-58
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- Publication type:
- Article
Stable RNA interference rules for silencing.
- Published in:
- Nature Cell Biology, 2014, v. 16, n. 1, p. 10, doi. 10.1038/ncb2895
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- Publication type:
- Article
TAp63 induces senescence and suppresses tumorigenesis in vivo.
- Published in:
- Nature Cell Biology, 2009, v. 11, n. 12, p. 1451, doi. 10.1038/ncb1988
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- Publication type:
- Article
Tumour suppression: something for nothing?
- Published in:
- Nature Cell Biology, 2002, v. 4, n. 12, p. E275, doi. 10.1038/ncb1202-e275
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- Publication type:
- Article
Direct coupling of the cell cycle and cell death machinery by E2F.
- Published in:
- Nature Cell Biology, 2002, v. 4, n. 11, p. 859, doi. 10.1038/ncb868
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- Publication type:
- Article
Specific pattern of p53 phosphorylation during nitric oxide-induced cell cycle arrest.
- Published in:
- Oncogene, 2000, v. 19, n. 54, p. 6369, doi. 10.1038/sj.onc.1204100
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- Publication type:
- Article