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- Title
Generation of Nanoliter Droplets on Demand at Hundred-Hz Frequencies.
- Authors
Jakiela, Slawomir; Debski, Pawel R.; Dabrowski, Bogdan; Garstecki, Piotr
- Abstract
We describe a precision micropump for generation of precisely metered micro-aliquots of liquid at high rates. The use of custom designed piezoelectric valves positioned externally to the microfluidic chip allows for on-demand formation of micro-droplets with online control of their individual volumes from nLs to μLs at frequencies up to 400 Hz. The system offers precision of administering volumes of 1% and of time of emission of <0.5 ms. The use of a piezoelectric actuator provides two distinct vistas for controlling the volume of the droplets--either by digital control of the "open" interval or by analogue tuning of the lumen of the valve. Fast and precise generation of droplets make this system a perfect constituent module for microfluidic high-speed combinatorial screening schemes.
- Subjects
MICROFLUIDICS; PIEZOELECTRIC devices; VALVES; ALIQUOTS (Chemistry); MICROCHANNEL flow
- Publication
Micromachines, 2014, Vol 5, Issue 4, p1002
- ISSN
2072-666X
- Publication type
Article
- DOI
10.3390/mi5041002