We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Direct Oxidation of Cycloalkanes to Cycloalkanones with Oxygen in Water.
- Authors
Staudt, Svenja; Burda, Edyta; Giese, Carolin; Müller, Christina A.; Marienhagen, Jan; Schwaneberg, Ulrich; Hummel, Werner; Drauz, Karlheinz; Gröger, Harald
- Abstract
It doesn′t take much to oxidize cycloalkanes directly to the corresponding cyclic ketones: molecular oxygen as the oxidant, water as the solvent, the cofactor NADP+ (and a little 2‐propanol to reduce it), as well as two catalytic enzymes—a hydroxylating P450 monooxygenase and an alcohol dehydrogenase (see scheme).
- Publication
Angewandte Chemie International Edition, 2013, Vol 52, Issue 8, p2359
- ISSN
1433-7851
- Publication type
Article
- DOI
10.1002/anie.201204464