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Age-dependent changes in TDP-43 levels in a mouse model of Alzheimer disease are linked to Aβ oligomers accumulation.
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- Molecular Neurodegeneration, 2010, v. 5, p. 51, doi. 10.1186/1750-1326-5-51
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- Article
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden.
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- Molecular Neurodegeneration, 2010, v. 5, p. 45, doi. 10.1186/1750-1326-5-45
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- Article
NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration.
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- Molecular Neurodegeneration, 2010, v. 5, p. 49, doi. 10.1186/1750-1326-5-49
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- Article
Fcϒ receptors are required for NF-κB signaling, microglial activation and dopaminergic neurodegeneration in an AAV-synuclein mouse model of Parkinson¿s disease.
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- Molecular Neurodegeneration, 2010, v. 5, p. 42, doi. 10.1186/1750-1326-5-42
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Identification of BACE1 cleavage sites in human voltage-gated sodium channel beta 2 subunit.
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- Molecular Neurodegeneration, 2010, v. 5, p. 61, doi. 10.1186/1750-1326-5-61
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Aminopeptidases do not directly degrade tau protein.
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- Molecular Neurodegeneration, 2010, v. 5, p. 48, doi. 10.1186/1750-1326-5-48
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DNA damage and cell cycle events implicate cerebellar dentate nucleus neurons as targets of Alzheimer's disease.
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- Molecular Neurodegeneration, 2010, v. 5, p. 60, doi. 10.1186/1750-1326-5-60
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Huntingtin cleavage product A forms in neurons and is reduced by gamma-secretase inhibitors.
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- Molecular Neurodegeneration, 2010, v. 5, p. 58, doi. 10.1186/1750-1326-5-58
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Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers.
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- Molecular Neurodegeneration, 2010, v. 5, p. 57, doi. 10.1186/1750-1326-5-57
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Neuroprotective effects and mechanism of cognitive-enhancing choline analogs JWB 1-84-1 and JAY 2-22-33 in neuronal cultureand Caenorhabditis elegans.
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- Molecular Neurodegeneration, 2010, v. 5, p. 59, doi. 10.1186/1750-1326-5-59
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- Article
ER stress response plays an important role inaggregation of -α-synuclein.
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- Molecular Neurodegeneration, 2010, v. 5, p. 56, doi. 10.1186/1750-1326-5-56
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α-synuclein induced synapse damage is enhanced by amyloid-β<sup>1-42</sup>.
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- Molecular Neurodegeneration, 2010, v. 5, p. 55, doi. 10.1186/1750-1326-5-55
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ADAR2-dependent RNA editing of GluR2 is involved in thiamine deficiency-induced alteration of calcium dynamics.
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- Molecular Neurodegeneration, 2010, v. 5, p. 54, doi. 10.1186/1750-1326-5-54
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- Article
Age-related synaptic loss of the medial olivocochlear efferent innervation.
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- Molecular Neurodegeneration, 2010, v. 5, p. 53, doi. 10.1186/1750-1326-5-53
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A hereditary spastic paraplegia mutation in kinesin-1A/KIF5A disrupts neurofilament transport.
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- Molecular Neurodegeneration, 2010, v. 5, p. 52, doi. 10.1186/1750-1326-5-52
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Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent andretromer-mediated.
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- Molecular Neurodegeneration, 2010, v. 5, p. 40, doi. 10.1186/1750-1326-5-40
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Abnormal iron metabolism in fibroblasts from a patient with the neurodegenerative disease hereditary ferritinopathy.
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- Molecular Neurodegeneration, 2010, v. 5, p. 50, doi. 10.1186/1750-1326-5-50
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Systemic treatment with liver X receptor agonists raises apolipoprotein E, cholesterol, and amyloid-β peptides in the cerebral spinal fluid of rats.
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- Molecular Neurodegeneration, 2010, v. 5, p. 44, doi. 10.1186/1750-1326-5-44
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MOLECULAR NEURODEGENERATION.
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- Molecular Neurodegeneration, 2010, v. 5, p. 43, doi. 10.1186/1750-1326-5-43
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Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model.
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- Molecular Neurodegeneration, 2010, v. 5, p. 47, doi. 10.1186/1750-1326-5-47
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- Article
Insulin deficiency exacerbates cerebral amyloidosis and behavioral deficits in an Alzheimer transgenic mouse model.
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- Molecular Neurodegeneration, 2010, v. 5, p. 46, doi. 10.1186/1750-1326-5-46
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Progranulin modulates zebrafish motoneuron development in vivo and rescues truncation defects associated with knockdown of Survivalmotor neuron 1.
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- Molecular Neurodegeneration, 2010, v. 5, p. 41, doi. 10.1186/1750-1326-5-41
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The biochemical aftermath of anti-amyloid immunotherapy.
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- Molecular Neurodegeneration, 2010, v. 5, p. 39, doi. 10.1186/1750-1326-5-39
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Phosphorylation regulates proteasomal-mediated degradation and solubility of TAR DNA binding protein-43 C-terminal fragments.
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- Molecular Neurodegeneration, 2010, v. 5, p. 33, doi. 10.1186/1750-1326-5-33
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Pericyte-specific expression of PDGF beta receptor in mouse models with normal and deficient PDGF beta receptor signaling.
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- Molecular Neurodegeneration, 2010, v. 5, p. 32, doi. 10.1186/1750-1326-5-32
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Presenilin-1 regulates induction of hypoxia inducible factor-1α: altered activation by a mutation associated with familial Alzheimer's disease.
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- Molecular Neurodegeneration, 2010, v. 5, p. 38, doi. 10.1186/1750-1326-5-38
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- Article
Increased expression of RXRα in dementia: an early harbinger for the cholesterol dyshomeostasis?
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- Molecular Neurodegeneration, 2010, v. 5, p. 36, doi. 10.1186/1750-1326-5-36
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- Article
Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells.
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- Molecular Neurodegeneration, 2010, v. 5, p. 29, doi. 10.1186/1750-1326-5-29
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- Article
BACE1<sup>-/-</sup> mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization.
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- Molecular Neurodegeneration, 2010, v. 5, p. 31, doi. 10.1186/1750-1326-5-31
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- Article
BACE1 gene variants do not influence BACE1 activity, levels of APP or AΒ isoforms in CSF in Alzheimer's disease.
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- Molecular Neurodegeneration, 2010, v. 5, p. 37, doi. 10.1186/1750-1326-5-37
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Prolonged Aβ treatment leads to impairment in the ability of primary cortical neurons to maintain K<sup>+</sup> and Ca<sup>2+</sup> homeostasis.
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- Molecular Neurodegeneration, 2010, v. 5, p. 30, doi. 10.1186/1750-1326-5-30
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Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain.
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- Molecular Neurodegeneration, 2010, v. 5, p. 35, doi. 10.1186/1750-1326-5-35
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Isoform of APOE with retained intron 3; quantitation and identification of an associated single nucleotide polymorphism.
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- Molecular Neurodegeneration, 2010, v. 5, p. 34, doi. 10.1186/1750-1326-5-34
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Localization of BDNF mRNA with the Huntington's disease protein in rat brain.
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- Molecular Neurodegeneration, 2010, v. 5, p. 22, doi. 10.1186/1750-1326-5-22
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No dramatic age-related loss of hair cells and spiral ganglion neurons in Bcl-2 over-expression mice or Bax null mice.
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- Molecular Neurodegeneration, 2010, v. 5, p. 28, doi. 10.1186/1750-1326-5-28
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The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease.
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- Molecular Neurodegeneration, 2010, v. 5, p. 26, doi. 10.1186/1750-1326-5-26
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Heat shock protein 90 in neurodegenerative diseases.
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- Molecular Neurodegeneration, 2010, v. 5, p. 24, doi. 10.1186/1750-1326-5-24
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Solving a 50 year mystery of a missing OPA1 mutation: more insights from the first family diagnosed with autosomal dominant optic atrophy.
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- Molecular Neurodegeneration, 2010, v. 5, p. 25, doi. 10.1186/1750-1326-5-25
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Effect of Apolipoprotein E ε4 on the association between health behaviors and cognitive function in late midlife.
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- Molecular Neurodegeneration, 2010, v. 5, p. 23, doi. 10.1186/1750-1326-5-23
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First evidence of overlaps between HIV-Associated Dementia (HAD) and non-viral neurodegenerative diseases: proteomic analysis of the frontal cortex from HIV+ patients with and without dementia.
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- Molecular Neurodegeneration, 2010, v. 5, p. 27, doi. 10.1186/1750-1326-5-27
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ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions.
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- Molecular Neurodegeneration, 2010, v. 5, p. 21, doi. 10.1186/1750-1326-5-21
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The inhibitory effect of pyrroloquinoline quinone on the amyloid formation and cytotoxicity of truncated alpha-synuclein.
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- Molecular Neurodegeneration, 2010, v. 5, p. 20, doi. 10.1186/1750-1326-5-20
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- Article
Endocytic pathways mediating oligomeric AΒ42 neurotoxicity.
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- Molecular Neurodegeneration, 2010, v. 5, p. 19, doi. 10.1186/1750-1326-5-19
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ApoE mimetic peptide decreases AΒ production in vitro and in vivo.
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- Molecular Neurodegeneration, 2010, v. 5, p. 16, doi. 10.1186/1750-1326-5-16
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- Article
Tetrabenazine is neuroprotective in Huntington's disease mice.
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- Molecular Neurodegeneration, 2010, v. 5, p. 18, doi. 10.1186/1750-1326-5-18
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High-efficiency transfection of cultured primary motor neurons to study protein localization, trafficking, and function.
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- Molecular Neurodegeneration, 2010, v. 5, p. 17, doi. 10.1186/1750-1326-5-17
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Soluble amyloid-β, effect on cerebral arteriolar regulation and vascular cells.
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- Molecular Neurodegeneration, 2010, v. 5, p. 15, doi. 10.1186/1750-1326-5-15
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Lysosomal function in macromolecular homeostatis and bioenergetics in Parkinson's disease.
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- Molecular Neurodegeneration, 2010, v. 5, p. 14, doi. 10.1186/1750-1326-5-14
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- Article
Phospholipase A<sub>2</sub> inhibitors protect against prion and Aβ mediated synapse degeneration.
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- Molecular Neurodegeneration, 2010, v. 5, p. 13, doi. 10.1186/1750-1326-5-13
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- Article
Dynamic transport and localization of alpha-synuclein in primary hippocampal neurons.
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- Molecular Neurodegeneration, 2010, v. 5, p. 1, doi. 10.1186/1750-1326-5-9
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