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- Title
Three-year relapse-free survival rates in childhood rhabdomyosarcoma of the head and neck: report from the Intergroup Rhabdomyosarcoma Study.
- Authors
Sutow, Wataru W.; Lindberg, Robert D.; Gehan, Edmund A.; Ragab, Abdelsalam H.; Raney, R. Beverly; Ruymann, Frederick; Soule, Edward H.; Sutow, W W; Lindberg, R D; Gehan, E A; Ragab, A H; Raney, R B Jr; Ruymann, F; Soule, E H
- Abstract
In 202 patients with rhabdomyosarcoma of the head and neck who registered in the first Intergroup Rhabdomyosarcoma Study, the primary lesions arose about the eye and orbit in 26%, in parameningeal sites in 46%, and in other head and neck areas in 28%. Histopathologically, 78% were embryonal-botryoid, 9% alveolar, 10% undifferentiated, and 3% extraosseous Ewing's types. Actual three-year relapse-free survival rates were calculated from data on 103 of these patients who were free of distant metastases at diagnosis and in whom follow-up had been completed for a three-year period. The actual relapse-free survival rates were 91% (21/23) for those with eye/orbit primaries, 46% (20/44) for those with parameningeal primaries, and 75% (27/36) for those with other head and neck sites affected. Among those with no clinical evidence of tumor activity at two years, 8% (6/75) had subsequent relapses.
- Publication
Cancer (0008543X), 1982, Vol 49, Issue 11, p2217
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(19820601)49:11<2217::AID-CNCR2820491102>3.0.CO;2-V