We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Measurement of Aortic Valve Coaptation and Effective Height Using Echocardiography in Patients with Ventricular Septal Defects and Aortic Valve Prolapse.
- Authors
Iwashima, Satoru; Uchiyama, Hiroki; Ishikawa, Takamichi; Takigiku, Kiyohiro; Takahashi, Ken; Toyono, Manatomo; Inoue, Nao; Nii, Masaki
- Abstract
Decreased coaptation height in adults has been identified as a marker of early valve failure. We evaluated aortic valve coaptation and effective height in healthy children and in children with a ventricular septal defect (VSD) with aortic cusp prolapse (ACP), using echocardiography. We included 45 subjects with VSD with ACP, 27 did not develop aortic regurgitation (AR) by ACP and 18 developed AR by ACP, and 83 healthy children as controls. Aortic root anatomy was estimated using the parasternal long-axis view. We measured the diameter of aortic valve (AV), coaptation height (CH), and effective height (EH) of the aortic valve. We defined the ACH (CH/AV ratio) and AEH (EH/AV ratio) indices as follows: $$\text{ACH }\!\!~\!\!\text{ index}\left( \text{ }\!\!\%\!\!\text{ } \right)\text{= }\!\!~\!\!\text{ }\frac{\text{CH}}{\text{AV}}\text{ }\!\!\times\!\!\text{ 100, AEH }\!\!~\!\!\text{ index}\left( \text{ }\!\!\%\!\!\text{ } \right)\text{= }\!\!~\!\!\text{ }\frac{\text{EH}}{\text{AV}}\text{ }\!\!\times\!\!\text{ 100}$$ . There were significant differences in ACH and AEH between the groups (control vs VSD with ACP vs VSD with ACP and AR, median ACH [%], 35.1 vs 32.0 vs 22.1; median AEH [%], 52.0 vs 48.0 vs 34.4, respectively; P < 0.01]). Intra-cardiac repair (ICR) was performed in 15 cases. Significant increases were observed in ACH and AEH before and after ICR (median ACH [%], before: 27.0, after: 32.7, P < 0.05; median AEH (%), before 38.5, after 45.8, P < 0.05). Measurement of ACH and AEH may allow direct and non-invasive assessment of the severity of VSD with ACP, which could aid clinicians in determining the need and timing for surgical intervention.
- Subjects
ECHOCARDIOGRAPHY; VENTRICULAR septal defects; PROLAPSE of bodily organs; AORTIC valve insufficiency; CONGENITAL heart disease
- Publication
Pediatric Cardiology, 2017, Vol 38, Issue 3, p608
- ISSN
0172-0643
- Publication type
Article
- DOI
10.1007/s00246-016-1555-8