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- Title
The Impact of Concomitant Left Ventricular Non-compaction with Congenital Heart Disease on Perioperative Outcomes.
- Authors
Ramachandran, Preeti; Woo, Jessica; Ryan, Thomas; Bryant, Roosevelt; Heydarian, Haleh; Jefferies, John; Towbin, Jeffrey; Lorts, Angela
- Abstract
Left ventricular non-compaction (LVNC) is a heterogeneous myocardial disorder characterized by prominent trabeculations and inter-trabecular recesses which may occur in association with congenital heart disease (CHD). To date, few studies have been performed to assess whether the concomitant diagnosis of LVNC affects the outcomes of CHD surgery. A retrospective review of patients with LVNC with CHD (LVNC-CHD), 0-5 years of age, was conducted. Patients with CHD without LVNC (CHD-only) and 0-5 years of age with similar diagnosis distribution were selected for comparison. Perioperative data, including CHD diagnosis, operative course, and postoperative complications were collected and compared between groups. LVNC-CHD was diagnosed in 26 children. Of the 26 with LVNC-CHD, 20 underwent surgery and these patients were compared with 276 CHD-only controls. Median total length of stay in the hospital was 12.5 days (IQR 5.5-63 days) in LVNC-CHD compared to 5 days (IQR 3-10 days) in CHD-only ( p < 0.005). Postoperative death, cardiac arrest, or need for ECMO or transplantation occurred in 6/20 (30 %) of the LVNC-CHD patients compared to 3/276 (1 %) of the CHD-only group ( p < 0.0001). LVNC-CHD patients had significantly longer hospital length of stay and higher perioperative complications compared to CHD-only patients without myocardial abnormalities. Pediatric cardiac care teams should be cognizant of the possibility of the increased perioperative risk associated with concomitant LVNC. Future prospective studies are warranted.
- Subjects
CONGENITAL heart disease; LEFT heart ventricle; COMPLICATIONS of cardiac surgery; PERIOPERATIVE care; HEALTH outcome assessment; PEDIATRIC cardiology; LENGTH of stay in hospitals; THERAPEUTICS
- Publication
Pediatric Cardiology, 2016, Vol 37, Issue 7, p1307
- ISSN
0172-0643
- Publication type
Article
- DOI
10.1007/s00246-016-1435-2