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- Title
In this issue: Emerging and provisional B and T cell lymphoma entities.
- Authors
Quintanilla-Martinez, Leticia
- Abstract
This month's issue includes a mini-series of 5 review papers on "Emerging and provisional B and T cell lymphoma entities." The mutational landscape of this disease is similar to that of EBV-negative cytotoxic PTCL cases and is characterized by frequent mutations in I TET2 i and/or I DNMT3A i , and JAK-STAT pathway genes, suggesting a potential role of clonal hematopoiesis in the pathogenesis of EBV-positive and -negative cytotoxic PTCL. Similarly, as in diffuse large B-cell lymphomas (DLBCL), gene expression profiling in T-cell lymphomas has been translated into immunohistochemical algorithms to facilitate the diagnosis of peripheral T cell lymphomas, not otherwise specified (PTCL, NOS).
- Subjects
B cell lymphoma; DIFFUSE large B-cell lymphomas; B cells; HEMATOPOIESIS; EXTRANODAL NK-T-cell lymphoma; ANAPLASTIC large-cell lymphoma; T-cell lymphoma
- Publication
Virchows Archiv: European Journal of Pathology, 2023, Vol 483, Issue 3, p277
- ISSN
0945-6317
- Publication type
Article
- DOI
10.1007/s00428-023-03597-4