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- Title
Clinical management of metformin overdose: A case report.
- Authors
Çolak, Şahin; Erdoğan, Mehmet Özgür; Yavuz, Burcu Genç; Akdemir, Hızır Ufuk; Ceppıoğlu, Seher Karslı; Yurdun, Türkan
- Abstract
Metformin is first-line therapy in diabetes mellitus treatment. Metformin intoxication may cause lactic acidosis. A 29-year-old woman presented to our emergency department with loss of consciousness. Arterial blood gas revealed severely increased anion gap lactic acidosis. Continuous venovenous hemofiltration was performed for 39 h. After extracorporeal treatment, the acidosis resolved and the patient became conscious. There is no specific treatment for metformin intoxication; current treatment is supportive only. Our aim is to highlight the diagnosis, chromatographic measurement of the drug blood level, and management of metformin overdose.
- Subjects
METFORMIN; HOSPITAL emergency services; LACTIC acidosis; THERAPEUTICS; LOSS of consciousness; BLOOD gases
- Publication
Journal of Experimental & Clinical Medicine / Deneysel ve Klinik Tip Dergisi, 2017, Vol 34, Issue 3, p203
- ISSN
1309-4483
- Publication type
Article
- DOI
10.5835/jecm.omu.34.03.009