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The transcriptome of Balamuthia mandrillaris trophozoites for structure-guided drug design.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-99903-8
By:
- Phan, Isabelle Q.;
- Rice, Christopher A.;
- Craig, Justin;
- Noorai, Rooksana E.;
- McDonald, Jacquelyn R.;
- Subramanian, Sandhya;
- Tillery, Logan;
- Barrett, Lynn K.;
- Shankar, Vijay;
- Morris, James C.;
- Van Voorhis, Wesley C.;
- Kyle, Dennis E.;
- Myler, Peter J.
Publication type:
Article
Enolase inhibitors as therapeutic leads for Naegleria fowleri infection.
Published in:
PLoS Pathogens, 2024, v. 20, n. 8, p. 1, doi. 10.1371/journal.ppat.1012412
By:
- Milanes, Jillian E.;
- Yan, Victoria C.;
- Pham, Cong-Dat;
- Muller, Florian;
- Kwain, Samuel;
- Rees, Kerrick C.;
- Dominy, Brian N.;
- Whitehead, Daniel C.;
- Millward, Steven W.;
- Bolejack, Madison;
- Shek, Roger;
- Tillery, Logan;
- Phan, Isabelle Q.;
- Staker, Bart;
- Moseman, E. Ashley;
- Zhang, Xiang;
- Ma, Xipeng;
- Jebet, Audriy;
- Yin, Xinmin;
- Morris, James C.
Publication type:
Article
A divergent protein kinase A regulatory subunit essential for morphogenesis of the human pathogen Leishmania.
Published in:
PLoS Pathogens, 2024, v. 20, n. 3, p. 1, doi. 10.1371/journal.ppat.1012073
By:
- Fischer Weinberger, Renana;
- Bachmaier, Sabine;
- Ober, Veronica;
- Githure, George B.;
- Dandugudumula, Ramu;
- Phan, Isabelle Q.;
- Almoznino, Michal;
- Polatoglou, Eleni;
- Tsigankov, Polina;
- Nitzan Koren, Roni;
- Myler, Peter J.;
- Boshart, Michael;
- Zilberstein, Dan
Publication type:
Article
Structure of uridine diphosphate N-acetylglucosamine pyrophosphorylase from Entamoeba histolytica.
Published in:
Acta Crystallographica: Section F, Structural Biology Communications, 2015, v. 71, n. 5, p. 560, doi. 10.1107/S2053230X1500179X
By:
- Edwards, Thomas E.;
- Gardberg, Anna S.;
- Phan, Isabelle Q. H.;
- Zhang, Yang;
- Staker, Bart L.;
- Myler, Peter J.;
- Lorimer, Donald D.
Publication type:
Article
Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures.
Published in:
Acta Crystallographica: Section F, Structural Biology Communications, 2015, v. 71, n. 5, p. 615, doi. 10.1107/S2053230X15004185
By:
- Phan, Isabelle Q. H.;
- Davies, Douglas R.;
- Moretti, Nilmar Silvio;
- Shanmugam, Dhanasekaran;
- Cestari, Igor;
- Anupama, Atashi;
- Fairman, James W.;
- Edwards, Thomas E.;
- Stuart, Kenneth;
- Schenkman, Sergio;
- Myler, Peter J.
Publication type:
Article
Structure of acid deoxyribonuclease.
Published in:
Nucleic Acids Research, 2017, v. 45, n. 10, p. 6217, doi. 10.1093/nar/gkx222
By:
- Varela-Ramirez, Armando;
- Abendroth, Jan;
- Mejia, Adrian A.;
- Phan, Isabelle Q.;
- Lorimer, Donald D.;
- Edwards, Thomas E.;
- Aguilera, Renato J.
Publication type:
Article
GeneDB—an annotation database for pathogens.
Published in:
Nucleic Acids Research, 2012, p. D98, doi. 10.1093/nar/gkr1032
By:
- Logan-Klumpler, Flora J.;
- De Silva, Nishadi;
- Boehme, Ulrike;
- Rogers, Matthew B.;
- Velarde, Giles;
- McQuillan, Jacqueline A.;
- Carver, Tim;
- Aslett, Martin;
- Olsen, Christian;
- Subramanian, Sandhya;
- Phan, Isabelle;
- Farris, Carol;
- Mitra, Siddhartha;
- Ramasamy, Gowthaman;
- Wang, Haiming;
- Tivey, Adrian;
- Jackson, Andrew;
- Houston, Robin;
- Parkhill, Julian;
- Holden, Matthew
Publication type:
Article
HAMAP: a database of completely sequenced microbial proteome sets and manually curated microbial protein families in UniProtKB/Swiss-Prot.
Published in:
Nucleic Acids Research, 2009, v. 37, n. suppl_1, p. D471, doi. 10.1093/nar/gkn661
By:
- Lima, Tania;
- Auchincloss, Andrea H.;
- Coudert, Elisabeth;
- Keller, Guillaume;
- Michoud, Karine;
- Rivoire, Catherine;
- Bulliard, Virginie;
- de Castro, Edouard;
- Lachaize, Corinne;
- Baratin, Delphine;
- Phan, Isabelle;
- Bougueleret, Lydie;
- Bairoch, Amos
Publication type:
Article
Experience using web services for biological sequence analysis.
Published in:
Briefings in Bioinformatics, 2008, v. 9, n. 6, p. 493, doi. 10.1093/bib/bbn029
By:
- Stockinger, Heinz;
- Attwood, Teresa;
- Nadeem Chohan, Shahid;
- Côté, Richard;
- Cudré-Mauroux, Philippe;
- Falquet, Laurent;
- Fernandes, Pedro;
- Finn, Robert D.;
- Hupponen, Taavi;
- Korpelainen, Eija;
- Labarga, Alberto;
- Laugraud, Aurelie;
- Lima, Tania;
- Pafilis, Evangelos;
- Pagni, Marco;
- Pettifer, Steve;
- Phan, Isabelle;
- Rahman, Nazim
Publication type:
Article
Applications of InterPro in protein annotation and genome analysis.
Published in:
Briefings in Bioinformatics, 2002, v. 3, n. 3, p. 285, doi. 10.1093/bib/3.3.285
By:
- Biswas, Margaret;
- O'Rourke, John F.;
- Camon, Evelyn;
- Fraser, Gill;
- Kanapin, Alexander;
- Karavidopoulou, Youla;
- Kersey, Paul;
- Kriventseva, Evgenia;
- Mittard, Virginie;
- Mulder, Nicola;
- Phan, Isabelle;
- Servant, Florence;
- Apweiler, Rolf
Publication type:
Article
Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors.
Published in:
Scientific Reports, 2017, p. 41074, doi. 10.1038/srep41074
By:
- Haft, Daniel H.;
- Pierce, Phillip G.;
- Mayclin, Stephen J.;
- Sullivan, Amy;
- Gardberg, Anna S.;
- Abendroth, Jan;
- Begley, Darren W.;
- Phan, Isabelle Q.;
- Staker, Bart L.;
- Myler, Peter J.;
- Marathias, Vasilios M.;
- Lorimer, Donald D.;
- Edwards, Thomas E.
Publication type:
Article
Combining Functional and Structural Genomics to Sample the Essential Burkholderia Structome.
Published in:
PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0053851
By:
- Baugh, Loren;
- Gallagher, Larry A.;
- Patrapuvich, Rapatbhorn;
- Clifton, Matthew C.;
- Gardberg, Anna S.;
- Edwards, Thomas E.;
- Armour, Brianna;
- Begley, Darren W.;
- Dieterich, Shellie H.;
- Dranow, David M.;
- Abendroth, Jan;
- Fairman, James W.;
- Fox III, David;
- Staker, Bart L.;
- Phan, Isabelle;
- Gillespie, Angela;
- Choi, Ryan;
- Nakazawa-Hewitt, Steve;
- Nguyen, Mary Trang;
- Napuli, Alberto
Publication type:
Article
Structure of a Burkholderia pseudomallei Trimeric Autotransporter Adhesin Head.
Published in:
PLoS ONE, 2010, v. 5, n. 9, p. 1, doi. 10.1371/journal.pone.0012803
By:
- Edwards, Thomas E.;
- Phan, Isabelle;
- Abendroth, Jan;
- Dieterich, Shellie H.;
- Masoudi, Amir;
- Wenjin Guo;
- Hewitt, Stephen N.;
- Kelley, Angela;
- Leibly, David;
- Brittnacher, Mitch J.;
- Staker, Bart L.;
- Miller, Samuel I.;
- Van Voorhis, Wesley C.;
- Myler, Peter J.;
- Stewart, Lance J.
Publication type:
Article
Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba.
Published in:
PLoS ONE, 2021, v. 16, n. 3, p. 1, doi. 10.1371/journal.pone.0241738
By:
- Tillery, Logan;
- Barrett, Kayleigh;
- Goldstein, Jenna;
- Lassner, Jared W.;
- Osterhout, Bram;
- Tran, Nathan L.;
- Xu, Lily;
- Young, Ryan M.;
- Craig, Justin;
- Chun, Ian;
- Dranow, David M.;
- Abendroth, Jan;
- Delker, Silvia L.;
- Davies, Douglas R.;
- Mayclin, Stephen J.;
- Calhoun, Brandy;
- Bolejack, Madison J.;
- Staker, Bart;
- Subramanian, Sandhya;
- Phan, Isabelle
Publication type:
Article
Infrastructure for the life sciences: design and implementation of the UniProt website.
Published in:
BMC Bioinformatics, 2009, v. 10, p. 1, doi. 10.1186/1471-2105-10-136
By:
- Jain, Eric;
- Bairoch, Amos;
- Duvaud, Severine;
- Phan, Isabelle;
- Redaschi, Nicole;
- Suzek, Baris E.;
- Martin, Maria J.;
- McGarvey, Peter;
- Gasteiger, Elisabeth
Publication type:
Article
A doublecortin-domain protein of Toxoplasma and its orthologues bind to and modify the structure and organization of tubulin polymers.
Published in:
BMC Molecular & Cell Biology, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s12860-020-0249-5
By:
- Leung, Jacqueline M.;
- Nagayasu, Eiji;
- Hwang, Yu-Chen;
- Liu, Jun;
- Pierce, Phillip G.;
- Phan, Isabelle Q.;
- Prentice, Robin A.;
- Murray, John M.;
- Hu, Ke
Publication type:
Article
Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module.
Published in:
Microorganisms, 2021, v. 9, n. 8, p. 1645, doi. 10.3390/microorganisms9081645
By:
- Schirmer, Tilman;
- de Beer, Tjaart A. P.;
- Tamegger, Stefanie;
- Harms, Alexander;
- Dietz, Nikolaus;
- Dranow, David M.;
- Edwards, Thomas E.;
- Myler, Peter J.;
- Phan, Isabelle;
- Dehio, Christoph
Publication type:
Article
Integr8 and Genome Reviews: integrated views of complete genomes and proteomes.
Published in:
Nucleic Acids Research, 2005, v. 33, n. suppl 1, p. d297
By:
- Kersey, Paul;
- Bower, Lawrence;
- Morris, Lorna;
- Horne, Alan;
- Petryszak, Robert;
- Kanz, Carola;
- Kanapin, Alexander;
- Das, Ujjwal;
- Michoud, Karine;
- Phan, Isabelle;
- Gattiker, Alexandre;
- Kulikova, Tamara;
- Faruque, Nadeem;
- Duggan, Karyn;
- Mclaren, Peter;
- Reimholz, Britt;
- Duret, Laurent;
- Penel, Simon;
- Reuter, Ingmar;
- Apweiler, Rolf
Publication type:
Article
The Proteome Analysis database: a tool for the in silico analysis of whole proteomes.
Published in:
Nucleic Acids Research, 2003, v. 31, n. 1, p. 414, doi. 10.1093/nar/gkg105
By:
- Pruess, Manuela;
- Fleischmann, Wolfgang;
- Kanapin, Alexander;
- Karavidopoulou, Youla;
- Kersey, Paul;
- Kriventseva, Evgenia;
- Mittard, Virginie;
- Mulder, Nicola;
- Phan, Isabelle;
- Servant, Florence;
- Apweiler, Rolf
Publication type:
Article
The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003.
Published in:
Nucleic Acids Research, 2003, v. 31, n. 1, p. 365, doi. 10.1093/nar/gkg095
By:
- Boeckmann, Brigitte;
- Bairoch, Amos;
- Apweiler, Rolf;
- Blatter, Marie-Claude;
- Estreicher, Anne;
- Gasteiger, Elisabeth;
- Martin, Maria J.;
- Michoud, Karine;
- O'Donovan, Claire;
- Phan, Isabelle;
- Pilbout, Sandrine;
- Schneider, Michel
Publication type:
Article
Proteome Analysis Database: online application of InterPro and CluSTr for the functional classification of proteins in whole genomes.
Published in:
Nucleic Acids Research, 2001, v. 29, n. 1, p. 44, doi. 10.1093/nar/29.1.44
By:
- Apweiler, Rolf;
- Biswas, Margaret;
- Fleischmann, Wolfgang;
- Kanapin, Alexander;
- Karavidopoulou, Youla;
- Kersey, Paul;
- Kriventseva, Evgenia V.;
- Mittard, Virginie;
- Mulder, Nicola;
- Phan, Isabelle;
- Zdobnov, Evgeni
Publication type:
Article
In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-83730-y
By:
- Phan, Isabelle Q.;
- Subramanian, Sandhya;
- Kim, David;
- Murphy, Michael;
- Pettie, Deleah;
- Carter, Lauren;
- Anishchenko, Ivan;
- Barrett, Lynn K.;
- Craig, Justin;
- Tillery, Logan;
- Shek, Roger;
- Harrington, Whitney E.;
- Koelle, David M.;
- Wald, Anna;
- Veesler, David;
- King, Neil;
- Boonyaratanakornkit, Jim;
- Isoherranen, Nina;
- Greninger, Alexander L.;
- Jerome, Keith R.
Publication type:
Article
Calmodulin-like proteins localized to the conoid regulate motility and cell invasion by Toxoplasma gondii.
Published in:
PLoS Pathogens, 2017, v. 13, n. 5, p. 1, doi. 10.1371/journal.ppat.1006379
By:
- Long, Shaojun;
- Brown, Kevin M.;
- Drewry, Lisa L.;
- Anthony, Bryan;
- Phan, Isabelle Q. H.;
- Sibley, L. David
Publication type:
Article
Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1.
Published in:
Scientific Reports, 2014, p. 1, doi. 10.1038/srep05944
By:
- Moen, Spencer O.;
- Abendroth, Jan;
- Fairman, James W.;
- Baydo, Ruth O.;
- Bullen, Jameson;
- Kirkwood, Jennifer L.;
- Barnes, Steve R.;
- Raymond, Amy C.;
- Begley, Darren W.;
- Henkel, Greg;
- McCormack, Ken;
- Tam, Vincent C.;
- Phan, Isabelle;
- Staker, Bart L.;
- Stacy, Robin;
- Myler, Peter J.;
- Lorimer, Don;
- Edwards, Thomas E.
Publication type:
Article
Backbone chemical shift assignments for the sensor domain of the Burkholderia pseudomallei histidine kinase RisS: 'missing' resonances at the dimer interface.
Published in:
Biomolecular NMR Assignments, 2015, v. 9, n. 2, p. 381, doi. 10.1007/s12104-015-9614-2
By:
- Buchko, Garry;
- Edwards, Thomas;
- Hewitt, Stephen;
- Phan, Isabelle;
- Voorhis, Wesley;
- Miller, Samuel;
- Myler, Peter
Publication type:
Article
Mycobacterium thermoresistibile as a source of thermostable orthologs of Mycobacterium tuberculosis proteins.
Published in:
Protein Science: A Publication of the Protein Society, 2012, v. 21, n. 7, p. 1093, doi. 10.1002/pro.2084
By:
- Edwards, Thomas E.;
- Liao, Reiling;
- Phan, Isabelle;
- Myler, Peter J.;
- Grundner, Christoph
Publication type:
Article
Toward a structome of Acinetobacter baumannii drug targets.
Published in:
Protein Science: A Publication of the Protein Society, 2020, v. 29, n. 3, p. 789, doi. 10.1002/pro.3826
By:
- Tillery, Logan M.;
- Barrett, Kayleigh F.;
- Dranow, David M.;
- Craig, Justin;
- Shek, Roger;
- Chun, Ian;
- Barrett, Lynn K.;
- Phan, Isabelle Q.;
- Subramanian, Sandhya;
- Abendroth, Jan;
- Lorimer, Donald D.;
- Edwards, Thomas E.;
- Van Voorhis, Wesley C.
Publication type:
Article
Structures of glyceraldehyde 3‐phosphate dehydrogenase in Neisseria gonorrhoeae and Chlamydia trachomatis.
Published in:
Protein Science: A Publication of the Protein Society, 2020, v. 29, n. 3, p. 768, doi. 10.1002/pro.3824
By:
- Barrett, Kayleigh F.;
- Dranow, David M.;
- Phan, Isabelle Q.;
- Michaels, Samantha A.;
- Shaheen, Shareef;
- Navaluna, Edelmar D.;
- Craig, Justin K.;
- Tillery, Logan M.;
- Choi, Ryan;
- Edwards, Thomas E.;
- Conrady, Deborah G.;
- Abendroth, Jan;
- Horanyi, Peter S.;
- Lorimer, Donald D.;
- Van Voorhis, Wesley C.;
- Zhang, Zhongsheng;
- Barrett, Lynn K.;
- Subramanian, Sandhya;
- Staker, Bart;
- Fan, Erkang
Publication type:
Article
Structural diversity in the Mycobacteria DUF3349 superfamily.
Published in:
Protein Science: A Publication of the Protein Society, 2020, v. 29, n. 3, p. 670, doi. 10.1002/pro.3758
By:
- Buchko, Garry W.;
- Abendroth, Jan;
- Robinson, John I.;
- Phan, Isabelle Q.;
- Myler, Peter J.;
- Edwards, Thomas E.
Publication type:
Article
<italic>Mycobacterium tuberculosis</italic> Rv3651 is a triple sensor‐domain protein.
Published in:
Protein Science: A Publication of the Protein Society, 2018, v. 27, n. 2, p. 568, doi. 10.1002/pro.3343
By:
- Abendroth, Jan;
- Frando, Andrew;
- Phan, Isabelle Q.;
- Staker, Bart L.;
- Myler, Peter J.;
- Edwards, Thomas E.;
- Grundner, Christoph
Publication type:
Article

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