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Targeting lysine demethylase 5 (KDM5) in mantle cell lymphoma.
Published in:
2024
By:
- Xu, Danmei;
- Bewicke-Copley, Findlay;
- Close, Karina;
- Okosun, Jessica;
- Gale, Robert Peter;
- Apperley, Jane;
- Weinstock, David M.;
- Wendel, Hans-Guido;
- Fitzgibbon, Jude
Publication type:
Letter
Synthetic lethality of drug-induced polyploidy and BCL-2 inhibition in lymphoma.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37216-2
By:
- Portelinha, Ana;
- da Silva Ferreira, Mariana;
- Erazo, Tatiana;
- Jiang, Man;
- Asgari, Zahra;
- de Stanchina, Elisa;
- Younes, Anas;
- Wendel, Hans-Guido
Publication type:
Article
Comparing the Effects of Rocaglates on Energy Metabolism and Immune Modulation on Cells of the Human Immune System.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5872, doi. 10.3390/ijms24065872
By:
- Schiffmann, Susanne;
- Henke, Marina;
- Seifert, Michelle;
- Ulshöfer, Thomas;
- Roser, Luise A.;
- Magari, Francesca;
- Wendel, Hans-Guido;
- Grünweller, Arnold;
- Parnham, Michael J.
Publication type:
Article
Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model.
Published in:
2008
By:
- Bordeleau, Marie-Eve;
- Robert, Francis;
- Gerard, Baudouin;
- Lindqvist, Lisa;
- Chen, Samuel M.H.;
- Wendel, Hans-Guido;
- Brem, Brigitte;
- Greger, Harald;
- Lowe, Scott W.;
- Porco Jr., John A.;
- Pelletier, Jerry;
- Porco, John A Jr
Publication type:
journal article
Characterization of a set of tumor suppressor microRNAs in T cell acute lymphoblastic leukemia.
Published in:
Science Signaling, 2014, v. 7, n. 352, p. 1, doi. 10.1126/scisignal.2005500
By:
- Sanghvi, Viraj R.;
- Mavrakis, Konstantinos J.;
- Van der Meulen, Joni;
- Boice, Michael;
- Wolfe, Andrew L.;
- Carty, Mark;
- Mohan, Prathibha;
- Rondou, Pieter;
- Socci, Nicholas D.;
- Benoit, Yves;
- Taghon, Tom;
- Van Vlierberghe, Pieter;
- Leslie, Christina S.;
- Speleman, Frank;
- Wendel, Hans-Guido
Publication type:
Article
Corrigendum: A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL).
Published in:
2011
By:
- Mavrakis, Konstantinos J.;
- Van Der Meulen, Joni;
- Wolfe, Andrew L.;
- Xiaoping Liu;
- Mets, Evelien;
- Taghon, Tom;
- Khan, Aly A.;
- Setti, Manu;
- Rondou, Pieter;
- Vandenberghe, Peter;
- Delabesse, Eric;
- Benoit, Yves;
- Socci, Nicholas B;
- Leslie, Christina S.;
- Van Vlierberghe, Pieter;
- Speleman, Frank;
- Wendel, Hans-Guido
Publication type:
Correction Notice
A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL).
Published in:
Nature Genetics, 2011, v. 43, n. 7, p. 673, doi. 10.1038/ng.858
By:
- Mavrakis, Konstantinos J.;
- Van Der Meulen, Joni;
- Wolfe, Andrew L.;
- Xiaoping Liu;
- Mets, Evelien;
- Taghon, Tom;
- Khan, Aly A.;
- Setti, Manu;
- Rondou, Pieter;
- Vandenberghe, Peter;
- Delabesse, Eric;
- Benoit, Yves;
- Socci, Nicholas B.;
- Leslie, Christina S.;
- Van Vlierberghe, Pieter;
- Speleman, Frank;
- Wendel, Hans-Guido
Publication type:
Article
Functional genomics lead to new therapies in follicular lymphoma.
Published in:
Annals of the New York Academy of Sciences, 2013, v. 1293, n. 1, p. 18, doi. 10.1111/nyas.12120
By:
- Oricchio, Elisa;
- Wendel, Hans‐Guido
Publication type:
Article
Rapamycin-Induced Feedback Activation of eIF4E-EIF4A Dependent mRNA Translation in Pancreatic Cancer.
Published in:
Cancers, 2023, v. 15, n. 5, p. 1444, doi. 10.3390/cancers15051444
By:
- Nguyen, Trang Uyen;
- Hector, Harrison;
- Pederson, Eric Nels;
- Lin, Jianan;
- Ouyang, Zhengqing;
- Wendel, Hans-Guido;
- Singh, Kamini
Publication type:
Article
Frequent 4EBP1 Amplification Induces Synthetic Dependence on FGFR Signaling in Cancer.
Published in:
Cancers, 2022, v. 14, n. 10, p. 2397, doi. 10.3390/cancers14102397
By:
- Mohan, Prathibha;
- Pasion, Joyce;
- Ciriello, Giovanni;
- Lailler, Nathalie;
- de Stanchina, Elisa;
- Viale, Agnes;
- van den Berg, Anke;
- Diepstra, Arjan;
- Wendel, Hans-Guido;
- Sanghvi, Viraj R.;
- Singh, Kamini
Publication type:
Article
NRF2 Activation Confers Resistance to eIF4A Inhibitors in Cancer Therapy.
Published in:
Cancers, 2021, v. 13, n. 4, p. 639, doi. 10.3390/cancers13040639
By:
- Sanghvi, Viraj R.;
- Mohan, Prathibha;
- Singh, Kamini;
- Cao, Linlin;
- Berishaj, Marjan;
- Wolfe, Andrew L.;
- Schatz, Jonathan H.;
- Lailler, Nathalie;
- de Stanchina, Elisa;
- Viale, Agnes;
- Wendel, Hans-Guido;
- Columbano, Amedeo
Publication type:
Article
Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia.
Published in:
Nature Cell Biology, 2010, v. 12, n. 4, p. 372, doi. 10.1038/ncb2037
By:
- Mavrakis, Konstantinos J.;
- Wolfe, Andrew L.;
- Oricchio, Elisa;
- Palomero, Teresa;
- de Keersmaecker, Kim;
- McJunkin, Katherine;
- Zuber, Johannes;
- James, Taneisha;
- Khan, Aly A.;
- Leslie, Christina S.;
- Parker, Joel S.;
- Paddison, Patrick J.;
- Tam, Wayne;
- Ferrando, Adolfo;
- Wendel, Hans-Guido
Publication type:
Article
GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells.
Published in:
Science Translational Medicine, 2019, v. 11, n. 485, p. N.PAG, doi. 10.1126/scitranslmed.aau7746
By:
- Staehr, Mette;
- Masakayan, Reed;
- Purdon, Terence J.;
- Smith, Eric L.;
- De Larrea, Carlos Fernandez;
- Brentjens, Renier J.;
- Harrington, Kim;
- Jones, Jon;
- Long, Thomas J.;
- Ghoddusi, Majid;
- Do, Trevor;
- Pham, Minh Thu;
- Brown, Jessica M.;
- Olson, Eric;
- Sather, Blythe;
- Ng, Khong Y.;
- Peguero, Elizabeth;
- Wendel, Hans-Guido;
- Wang, Xiuyan;
- Riviere, Isabelle
Publication type:
Article
Genetic and epigenetic inactivation of SESTRIN1 controls mTORC1 and response to EZH2 inhibition in follicular lymphoma.
Published in:
Science Translational Medicine, 2017, v. 9, n. 396, p. 1, doi. 10.1126/scitranslmed.aak9969
By:
- Oricchio, Elisa;
- Katanayeva, Natalya;
- Donaldson, Maria Christine;
- Sungalee, Stephanie;
- Joyce, Pasion P.;
- Béguelin, Wendy;
- Battistello, Elena;
- Sanghvi, Viraj R.;
- Man Jiang;
- Yanwen Jiang;
- Teater, Matt;
- Parmigiani, Anita;
- Budanov, Andrei V.;
- Fong Chun Chan;
- Shah, Sohrab P.;
- Kridel, Robert;
- Melnick, Ari M.;
- Ciriello, Giovanni;
- Wendel, Hans-Guido
Publication type:
Article
CAR-directed cytotoxicity of NK cells: an alternative tool to treat and to study multiple myeloma and NK biology.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e355, doi. 10.1016/j.clml.2019.09.586
By:
- Ng, Khong;
- Pasion, Joyce;
- Wendel, Hans-Guido
Publication type:
Article
Transcriptional and Translational Dynamics of Zika and Dengue Virus Infection.
Published in:
Viruses (1999-4915), 2022, v. 14, n. 7, p. N.PAG, doi. 10.3390/v14071418
By:
- Singh, Kamini;
- Martinez, Maria Guadalupe;
- Lin, Jianan;
- Gregory, James;
- Nguyen, Trang Uyen;
- Abdelaal, Rawan;
- Kang, Kristy;
- Brennand, Kristen;
- Grünweller, Arnold;
- Ouyang, Zhengqing;
- Phatnani, Hemali;
- Kielian, Margaret;
- Wendel, Hans-Guido
Publication type:
Article
Rocaglates as Antivirals: Comparing the Effects on Viral Resistance, Anti-Coronaviral Activity, RNA-Clamping on eIF4A and Immune Cell Toxicity.
Published in:
Viruses (1999-4915), 2022, v. 14, n. 3, p. 519, doi. 10.3390/v14030519
By:
- Obermann, Wiebke;
- Friedrich, Alexandra;
- Madhugiri, Ramakanth;
- Klemm, Paul;
- Mengel, Jan Philipp;
- Hain, Torsten;
- Pleschka, Stephan;
- Wendel, Hans-Guido;
- Hartmann, Roland K.;
- Schiffmann, Susanne;
- Ziebuhr, John;
- Müller, Christin;
- Grünweller, Arnold
Publication type:
Article
Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy.
Published in:
Nature, 2004, v. 428, n. 6980, p. 332, doi. 10.1038/nature02369
By:
- Wendel, Hans-Guido;
- de Stanchina, Elisa;
- Friedman, Jordan S.;
- Malina, Abba;
- Ray, Sagarika;
- Kogan, Scott;
- Cordon-Cardo, Carlos;
- Pelletier, Jerry;
- Lowe, Scott W.
Publication type:
Article
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer.
Published in:
Nature, 2014, v. 513, n. 7516, p. 65, doi. 10.1038/nature13485
By:
- Wolfe, Andrew L.;
- Rodrigo, Christina M.;
- Porco, John A.;
- Rondou, Pieter;
- Speleman, Frank;
- de Stanchina, Elisa;
- Teruya-Feldstein, Julie;
- Pelletier, Jerry;
- Singh, Kamini;
- Zhong, Yi;
- Drewe, Philipp;
- Rätsch, Gunnar;
- Rajasekhar, Vinagolu K.;
- Sanghvi, Viraj R.;
- Jiang, Man;
- Zhao, Chunying;
- Wendel, Hans-Guido;
- Mavrakis, Konstantinos J.;
- Roderick, Justine E.;
- Kelliher, Michelle A.
Publication type:
Article
Ectopic activation of the miR-200c–EpCAM axis enhances antitumor T cell responses in models of adoptive cell therapy.
Published in:
Science Translational Medicine, 2021, v. 13, n. 611, p. 1, doi. 10.1126/scitranslmed.abg4328
By:
- Zhang, Minggang;
- Zhao, Zeguo;
- Pritykin, Yuri;
- Hannum, Margaret;
- Scott, Andrew C.;
- Kuo, Fengshen;
- Sanghvi, Viraj;
- Chan, Timothy A.;
- Seshan, Venkatraman;
- Wendel, Hans-Guido;
- Schietinger, Andrea;
- Sadelain, Michel;
- Huse, Morgan
Publication type:
Article
RiboDiff: detecting changes of mRNA translation efficiency from ribosome footprints.
Published in:
Bioinformatics, 2017, v. 33, n. 1, p. 139, doi. 10.1093/bioinformatics/btw585
By:
- Yi Zhong;
- Karaletsos, Theofanis;
- Drewe, Philipp;
- Sreedharan, Vipin T.;
- Kuo, David;
- Singh, Kamini;
- Wendel, Hans-Guido;
- Rätsch, Gunnar
Publication type:
Article

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