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- Title
Genome-Wide Association Studies in Pediatric Endocrinology.
- Authors
Dauber, Andrew; Hirschhorn, Joel N.
- Abstract
Genome-wide association (GWA) studies are a powerful tool for understanding the genetic underpinnings of human disease. In this article, we briefly review the role and findings of GWA studies in type 1 diabetes, stature, pubertal timing, obesity, and vitamin D deficiency. We then discuss the present and future implications of these findings with regards to disease prediction, uncovering basic biology, and the development of novel therapeutic agents. Copyright © 2011 S. Karger AG, Basel
- Subjects
GENOMICS; PEDIATRIC endocrinology; GENETICS of diabetes; OBESITY genetics; SHORT stature; VITAMIN D deficiency; PUBERTY; GENETICS
- Publication
Hormone Research in Paediatrics, 2011, Vol 75, Issue 5, p322
- ISSN
1663-2818
- Publication type
Article
- DOI
10.1159/000326684