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- Title
Neuroimaging assessment in Down syndrome: a pictorial review.
- Authors
Rodrigues, Marta; Nunes, Joana; Figueiredo, Sofia; Martins de Campos, António; Geraldo, Ana Filipa
- Abstract
Down syndrome (DS), or trisomy 21, is the leading genetic cause of intellectual incapacity worldwide, with a reported incidence of about 1 in 1,000 to 1 in 1,100 live births. Besides the several commonly known physical features characteristic of this syndrome present at birth, DS may additionally affect every organ system. In addition, despite the large number of published papers concerning this syndrome, there is scarce literature focusing specifically in the typical neuroimaging features associated with this condition. The aim of this paper is to review and systematize the distinctive characteristics and abnormalities of the central nervous system, head and neck, and spine present in DS patients that should actively be searched for and evaluated by radiologists and/or neuroradiologists.
- Subjects
DOWN syndrome; CENTRAL nervous system; CHILDBIRTH; BRAIN imaging; BRAIN abnormalities; TRISOMY 18 syndrome
- Publication
Insights into Imaging, 2019, Vol 10, Issue 1, p1
- ISSN
1869-4101
- Publication type
Article
- DOI
10.1186/s13244-019-0729-3