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- Title
Kocher-Debré-Semelaigne syndrome with rhabdomyolysis and increased creatinine.
- Authors
Cimbek, Emine Ayça; Şen, Yaşar; Yuca, Sevil Arı; Çam, Demet; Gür, Celal; Peru, Harun
- Abstract
Association of Kocher-Debré-Semelaigne syndrome-a myopathy of hypothyroidism in childhood characterized by muscular hypertrophy, with rhabdomyolysis is very rare. We present a case of Kocher-Debré-Semelaigne syndrome with rhabdomyolysis secondary to Hashimoto's thyroiditis. He had muscular symptoms simulating poly/dermatomyositis, massively elevated creatine kinase (CK) levels and high creatinine levels. All of the findings reversed on treatment of hypothyroidism. The response to the therapy strongly suggested that Kocher-Debré-Semelaigne (KDS) syndrome was the underlying etiology. Serum thyroid- stimulating hormone levels should be routinely determined in all patients with muscular symptoms and/or elevation of CK and creatinine, keeping KDS syndrome in mind.
- Publication
Journal of Pediatric Endocrinology & Metabolism, 2015, Vol 28, Issue 11/12, p1383
- ISSN
0334-018X
- Publication type
Article
- DOI
10.1515/jpem-2014-0411