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- Title
The peripheral CD138<sup>+</sup> population but not the CD138<sup>−</sup> population contains myeloma clonogenic cells in plasma cell leukaemia patients.
- Authors
Chiron, David; Surget, Sylvanie; Maïga, Sophie; Bataille, Régis; Moreau, Philippe; Le Gouill, Steven; Amiot, Martine; Pellat-Deceunynck, Catherine
- Abstract
The article reports that stem cell CD 138+ molecule is better for targeted therapies in multiple myeloma (MM) as compared with CD 138 -. It further presents several characteristics of the nature of B-cells present in these stem cells including these molecules including B-cells are biased towards plasma cells, it exist in patients with multiple myeloma (MM), and in cell cycles. It also presents a study which determines that CD 138 are good for MM patients.
- Subjects
MYELOID leukemia; INFANTS; STEM cells; MULTIPLE myeloma; CELL cycle
- Publication
British Journal of Haematology, 2012, Vol 156, Issue 5, p679
- ISSN
0007-1048
- Publication type
Article
- DOI
10.1111/j.1365-2141.2011.08904.x