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- Title
Outcome of adults with sickle cell disease admitted to critical care – experience of a single institution in the UK.
- Authors
Gardner, Kate; Bell, Cathy; Bartram, Jack L.; Allman, Marlene; Awogbade, Moji; Rees, David C.; Ervine, Max; Thein, Swee L.
- Abstract
Sickle cell disease (SCD) patients are perceived to have a high mortality when admitted to the Critical Care Unit (CCU). We performed a retrospective analysis of all adult sickle admissions to CCU at a single centre over an 8-year period (1 January 2000 to 31 December 2007). Thirty-eight patients (14 male) were admitted 46 times to CCU; the commonest reasons for admission were acute chest syndrome (14, 30%), multi-organ failure (8, 17%) and planned post-elective surgery (7, 15%). CCU mortality for SCD patients was 19·6%, comparable to a CCU-wide mortality of 17·6% during the study period in the same institution. Re-admission to CCU was high (16% over the 8-year period) but did not increase mortality risk.
- Subjects
SICKLE cell anemia; HOSPITAL admission &; discharge; INTENSIVE care units; RETROSPECTIVE studies; MORTALITY; RESPIRATORY insufficiency; PATIENTS
- Publication
British Journal of Haematology, 2010, Vol 150, Issue 5, p610
- ISSN
0007-1048
- Publication type
Article
- DOI
10.1111/j.1365-2141.2010.08271.x