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Alzheimer's disease brain contains tau fractions with differential prion-like activities.
- Published in:
- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01127-4
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- Publication type:
- Article
Activation of protein phosphatase 2B and hyperphosphorylation of Tau in Alzheimer's disease.
- Published in:
- 2011
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- Publication type:
- journal article
PP2A regulates tau phosphorylation directly and also indirectly via activating GSK-3beta.
- Published in:
- 2010
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- Publication type:
- journal article
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome.
- Published in:
- 2008
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- Publication type:
- journal article
Multi-Targets: An Unconventional Drug Development Strategy for Alzheimer's Disease.
- Published in:
- Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.837649
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- Publication type:
- Article
Deregulation of brain insulin signaling in Alzheimer's disease.
- Published in:
- Neuroscience Bulletin, 2014, v. 30, n. 2, p. 282, doi. 10.1007/s12264-013-1408-x
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- Publication type:
- Article
Tau antibody 77G7 targeting microtubule binding domain suppresses proteopathic tau to seed tau aggregation.
- Published in:
- CNS Neuroscience & Therapeutics, 2022, v. 28, n. 12, p. 2245, doi. 10.1111/cns.13970
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- Publication type:
- Article
Quantitative proteomics identifies altered O-GlcNAcylation of structural, synaptic and memory-associated proteins in Alzheimer's disease.
- Published in:
- Journal of Pathology, 2017, v. 243, n. 1, p. 78, doi. 10.1002/path.4929
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- Publication type:
- Article
Prophylactic effect of passive immunotherapy with tau antibody 43D in 3xTg‐AD mice.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.079370
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- Publication type:
- Article
Tau antibody 77G7 targeting microtubule binding domain suppresses oligomeric tau to seed tau aggregation.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.067128
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- Publication type:
- Article
P4‐162: CYCLIC AMP‐DEPENDENT PROTEIN KINASE PHOSPHORYLATES TDP‐43 AND MODULATES ITS FUNCTION IN TAU MRNA PROCESSING.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1336, doi. 10.1016/j.jalz.2019.06.3824
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- Publication type:
- Article
P4‐152: PATHOLOGICAL TAU FROM ALZHEIMER'S BRAIN INDUCES SITE‐SPECIFIC HYPERPHOSPHORYLATION AND SDS‐ AND REDUCING AGENT‐RESISTANT HIGH MOLECULAR WEIGHT AGGREGATION OF TAU IN VIVO.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1333, doi. 10.1016/j.jalz.2019.06.3814
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- Publication type:
- Article
P2‐181: SUBACUTE TO CHRONIC ALZHEIMER‐LIKE ALTERATIONS AFTER CONTROLLED CORTICAL IMPACT IN TG/HTAU MICE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P645, doi. 10.1016/j.jalz.2019.06.2588
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- Publication type:
- Article
P1‐205: INTRANASAL ADMINISTRATION OF INSULIN PREVENTS CHRONIC COGNITIVE IMPAIRMENT AND NEURONAL APOPTOSIS INDUCED BY GENERAL ANESTHESIA IN NEONATAL MICE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P315, doi. 10.1016/j.jalz.2019.06.760
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- Publication type:
- Article
P3‐183: RELEVANCE OF PHOSPHORYLATION AND TRUNCATION OF TAU TO THE ETIOPATHOGENESIS OF ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1137, doi. 10.1016/j.jalz.2018.06.1541
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- Publication type:
- Article
P1‐240: TEMPLATION AND PROPAGATION OF TAU PATHOLOGY BY ALZHEIMER TAU IN C57BL/6 MICE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P370, doi. 10.1016/j.jalz.2018.06.245
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- Publication type:
- Article
O1‐06‐03: IMMUNOTHERAPY‐TARGETING TAU BLOCKS TAU PATHOLOGY INDUCED BY ALZHEIMER'S HYPERPHOSPHORYLATED TAU IN TRIPLE‐TRANSGENIC AD MICE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P231, doi. 10.1016/j.jalz.2018.06.2362
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- Publication type:
- Article
Gut Microbiota and Immunotherapy for Alzheimer's Disease.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 23, p. 15230, doi. 10.3390/ijms232315230
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- Publication type:
- Article
Neonatal Exposure to Anesthesia Leads to Cognitive Deficits in Old Age: Prevention with Intranasal Administration of Insulin in Mice.
- Published in:
- Neurotoxicity Research, 2020, v. 38, n. 2, p. 299, doi. 10.1007/s12640-020-00223-y
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- Publication type:
- Article
CREB regulates the expression of neuronal glucose transporter 3: a possible mechanism related to impaired brain glucose uptake in Alzheimer’s disease.
- Published in:
- Nucleic Acids Research, 2013, v. 41, n. 5, p. 3240, doi. 10.1093/nar/gks1227
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- Publication type:
- Article
Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A.
- Published in:
- Nucleic Acids Research, 2011, v. 39, n. 14, p. 6161, doi. 10.1093/nar/gkr195
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- Publication type:
- Article
Young blood plasma reduces Alzheimer's disease-like brain pathologies and ameliorates cognitive impairment in 3×Tg-AD mice.
- Published in:
- Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13195-020-00639-w
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- Publication type:
- Article
Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 × Tg-AD mice.
- Published in:
- Alzheimer's Research & Therapy, 2018, v. 10, p. 1, doi. 10.1186/s13195-018-0341-7
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- Publication type:
- Article
Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes.
- Published in:
- Journal of Pathology, 2011, v. 225, n. 1, p. 54, doi. 10.1002/path.2912
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- Publication type:
- Article
TDP-43 REGULATES ALTERNATIVE SPLICING OF TAU EXON 10: IMPLICATION IN THE PATHOGENESIS OF TAUOPATHIES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1301, doi. 10.1016/j.jalz.2017.06.1981
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- Publication type:
- Article
INTRANASAL ADMINISTRATION OF INSULIN PREVENTS ANESTHESIA-INDUCED COGNITIVE IMPAIRMENT AND CHRONIC NEUROBEHAVIORAL CHANGES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P633, doi. 10.1016/j.jalz.2017.06.722
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- Publication type:
- Article
TAU IMMUNOTHERAPY PREVENTS THE SPREAD AND PROMOTES THE CLEARANCE OF PATHOLOGY IN MICE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P888, doi. 10.1016/j.jalz.2017.07.287
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- Publication type:
- Article
C-TERMINAL TRUNCATION OF GSK-3β ENHANCES ITS DEPHOSPHORYLATION BY PP2A.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P553, doi. 10.1016/j.jalz.2017.07.153
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- Publication type:
- Article
O-GlcNAcylation: A regulator of tau pathology and neurodegeneration.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, n. 10, p. 1078, doi. 10.1016/j.jalz.2016.02.011
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- Publication type:
- Article
O-GLCNACYLATION AMELIORATES ISCHEMIA-INDUCED CEREBRAL INJURY.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1048, doi. 10.1016/j.jalz.2016.06.2184
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- Publication type:
- Article
TDP-43 SUPPRESSES TAU EXPRESSION VIA PROMOTING ITS MRNA INSTABILITY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P390, doi. 10.1016/j.jalz.2016.06.735
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- Publication type:
- Article
Regulation of alternative splicing of tau exon 10 by dual-specificity tyrosine-phosphorylation-regulated kinase 1A.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P203, doi. 10.1016/j.jalz.2015.07.197
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- Publication type:
- Article
Intranasal insulin prevents anesthesia-induced spatial memory deficit in mice.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P860, doi. 10.1016/j.jalz.2015.08.036
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- Publication type:
- Article
Cerebral ischemia-induced elevation of O-GlcNAcylation causes AKT inhibition and apoptosis
- Published in:
- 2012
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- Publication type:
- Abstract
O-GlcNAcylated tau: A link between impaired glucose metabolism and neurodegeneration in Alzheimer's disease
- Published in:
- 2012
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- Publication type:
- Abstract
CREB regulates the expression of neuronal glucose transporter 3: A mechanism leading to impaired brain glucose uptake in Alzheimer's disease
- Published in:
- 2012
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- Publication type:
- Abstract
Truncation of GSK-3beta by calpain I contributes to the hyperphosphorylation of tau in the Alzheimer's brain
- Published in:
- 2012
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- Publication type:
- Abstract
Differential regulation of the alternative splicing of tau exon 10 by protein kinase A isoforms
- Published in:
- 2011
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- Publication type:
- Abstract
Developmental regulation of protein O-GlcNAcylation, O-GlcNAc transferase, and O-GlcNAcase in mammalian brain
- Published in:
- 2011
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- Publication type:
- Abstract
Molecular basis of cognitive improvement of pioglitazone and rosiglitazone
- Published in:
- 2010
- By:
- Publication type:
- Abstract
Regulation of Akt by O-GlcNAcylation in various cell types: implication in Alzheimer's Disease
- Published in:
- 2010
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- Publication type:
- Abstract
Dysregulation of brain insulin signaling: A mechanistic link between diabetes and Alzheimer's disease
- Published in:
- 2010
- By:
- Publication type:
- Abstract
Splicing factor SC35 regulates the alternative splicing of tau exon 10
- Published in:
- 2010
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- Publication type:
- Abstract
Overexpression of Dyrk1A dysregulates the alternative splicing of tau exon 10
- Published in:
- 2010
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- Publication type:
- Abstract
Truncation of GSK-3β by activated calpain I in Alzheimer brain enhances its biological activity
- Published in:
- 2010
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- Publication type:
- Abstract
Molecular basis of diabetes as a risk for Alzheimer's disease
- Published in:
- 2010
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- Publication type:
- Abstract
Excitotoxic damage deregulates tau phosphorylation: Implication to Alzheimer's disease
- Published in:
- 2009
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- Publication type:
- Abstract
Truncation and activation of Dyrk1A in Alzheimer's disease brain by activated calpain I
- Published in:
- 2009
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- Publication type:
- Abstract
P2-155: Phosphorylation of SC35 by Dyrk1A inhibits its promotion of tau exon 10 inclusion
- Published in:
- 2008
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- Publication type:
- Abstract
P2-148: Involvement of 9G8 in alternative splicing of tau exon 10
- Published in:
- 2008
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- Publication type:
- Abstract