We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Determining the role of genetic risk scores in symptomatic cancer detection.
- Authors
Bailey, Sarah ER; Butler, Celia AM; Katsampouris, Evangelos; Kessler, Larry; Quaife, Samantha L; Saya, Sibel; Merriel, Samuel WD
- Abstract
The potential psychosocial and behavioural impacts of genome testing in the context of cancer screening have been explored;[13] however, it is not known how this would translate for those who present to primary care with possible symptoms of an underlying cancer. Improving cancer diagnosis is a national priority in the UK, with the I NHS Long Term Plan i pledging to increase the percentage of cancers found at an early stage from 50% to 75% by 2028.[1] Patients with cancer diagnosed at an early stage generally have better outcomes and longer survival. A recent study showed that a prostate cancer GRS could improve risk stratification in primary care.[8] Most strategies to improve early cancer detection in primary care involve improving the selection of patients for referral and investigation, introducing new triage tests, or encouraging earlier symptom recognition in patients and clinicians.
- Subjects
DISEASE risk factors; EARLY detection of cancer; PROSTATE cancer; WHOLE genome sequencing; PATIENT selection; CANCER diagnosis
- Publication
British Journal of General Practice, 2023, Vol 73, Issue 728, p106
- ISSN
0960-1643
- Publication type
Article
- DOI
10.3399/bjgp23x732069