We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
COVCOG: Immediate and long-term cognitive improvement after cognitive versus emotion management psychoeducation programs - a randomized trial in covid patients with neuropsychological difficulties.
- Authors
Willems, Sylvie; Didone, Vincent; Cabello Fernandez, Carmen; Delrue, Gael; Slama, Hichem; Fery, Patrick; Goin, Julien; Della Libera, Clara; COVCOG Group; Moutschen, Michel; Rousseau, Anne-Françoise; Dupuis, Gilles; Billet, Maud; Charonitis, Maëlle; Demoulin, Valentine; Dethier, Marie; Guillemin, Camille; Kreusch, Fanny; Leens, Fréderique; Léonard, Christina
- Abstract
Background: Cognitive difficulties are a frequent complaint in long COVID and persist for more than a year post- infection. There is a lack of evidence-based data on effective intervention strategies. Non-pharmacological intervention programs that are used with other neurological populations have not yet been the subject of controlled trials. COVCOG is a multicentric, randomized trial comparing cognitive intervention and a cognitive-behavioural counselling. Methods/design: Patients with long covid are selected and recruited at least three months post-infection. Patients are randomised in a 1:1 ratio into the cognitive (neuropsychological psychoeducation) and affective (emotion management with cognitive-behavioural counselling) intervention arms. The inclusion of 130 patients is planned. The cognitive intervention includes psycho-educational modules on fatigue and sleep, attention and working memory, executive functions and long-term memory. The affective intervention includes modules on emotion recognition and communication, uncertainty management and behavioral activation. The main objective is to reduce cognitive complaints 2 months after the intervention. A Follow-up is also planned at 8 months. Discussion: Given the long-term effects of Covid on cognition and the negative effects of cognitive impairment on quality of life and social participation, it is important to determine whether low-dose, non-pharmacological interventions can be effective. The trial will determine which of the usual types of intervention is the most effective. Trial registration: Clinicaltrials.gov Number: NCT05167266 (21/12/ 2021).
- Subjects
PSYCHOEDUCATION; POST-acute COVID-19 syndrome; EXECUTIVE function; EMOTIONS; COVID-19; NEUROPSYCHOLOGICAL rehabilitation
- Publication
BMC Neurology, 2023, Vol 23, Issue 1, p1
- ISSN
1471-2377
- Publication type
Article
- DOI
10.1186/s12883-023-03346-9